Results 61 to 70 of about 59,618 (284)

Cytokine Profile in Quadriceps Muscles of Patients with Severe Chronic Obstructive Pulmonary Disease [PDF]

, 2008
BACKGROUND: Systemic proinflammatory cytokines and oxidative stress have been described in association with peripheral muscle wasting and weakness of patients with severe chronic obstructive pulmonary disease (COPD), but their expression in skeletal ...
Gea, J., Galdiz, J.B., Polkey, M.I., Gosker, H.R.; id_orcid, Barreiro, E., Schols, A.M., Gosker, H.R., Swallow, E.B., Coronell, C.   +8 more
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

CD4+ T cells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection

Cell Reports, 2023
Summary: Infections cause catabolism of fat and muscle stores. Traditionally, studies have focused on understanding how the innate immune system contributes to energy stores wasting, while the role of the adaptive immune system remains elusive.
Samuel E. Redford, Siva Karthik Varanasi, Karina K. Sanchez, Natalia R. Thorup, Janelle S. Ayres   +4 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Facts about Wildlife Diseases: Chronic Wasting Disease (CWD)

EDIS
This article is intended to summarize for the general public, and particularly hunters, farmed cervid owners, and landowners, what is currently known about chronic wasting disease (CWD) and its impacts, with information about practices to minimize ...
Bridget B. Baker, Samantha M. Wisely, Anastasia Postowski, Kristen Wilson   +3 more
doaj   +3 more sources

Surveillance Optimization Project for Chronic Wasting Disease dataset for Michigan, US, 2001-2021

, 2023
This dataset contains one file containing data from the Michigan Department of Natural Resources. The data was shared with the Cornell Wildlife Health Lab (CWHL) at Cornell University for the purpose of the Surveillance Optimization Project for Chronic ...
Michigan Department of Natural Resources
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Protein-Energy Wasting and Associated Factors Among Chronic Kidney Disease Patients at St. Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia

International Journal of Nephrology and Renovascular Disease, 2020
Chaltu Merga,1 Meron Girma,2 Melese Sinaga Teshome2 1Department of Nutrition, Ambo University, Ambo, Ethiopia; 2Department of Nutrition and Dietetics, Faculty of Public Health, Health Institute, Jimma University, Jimma, EthiopiaCorrespondence: Melese ...
Merga C, Girma M, Teshome MS
doaj  

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Human Prion Disease and Relative Risk Associated with Chronic Wasting Disease

Emerging Infectious Diseases, 2006
The transmission of the prion disease bovine spongiform encephalopathy (BSE) to humans raises concern about chronic wasting disease (CWD), a prion disease of deer and elk. In 7 Colorado counties with high CWD prevalence, 75% of state hunting licenses are
W. John Pape, Jeri Forster, C. Alan Anderson, Patrick Bosque, Patrick Bosque, Michael Miller   +5 more
doaj   +1 more source