Results 131 to 140 of about 2,366 (155)
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Chrysophanol inhibits endoplasmic reticulum stress in cerebral ischemia and reperfusion mice
European Journal of Pharmacology, 2018Endoplasmic reticulum (ER) stress plays a critical role in mediating ischemia/reperfusion (I/R) damage in the brain. Our previous study showed that Chrysophanol (CHR) alleviated cerebral ischemic injury in mice and nuclear factor-κB (NF-κB) involved in its neuroprotective effect, but the precise mechanism remains not fully understood. The present study
Yongmei, Zhao +8 more
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Chrysophanol: A Promising Agent in Modulating Inflammatory Pathways
Recent Advances in Inflammation & Allergy Drug DiscoveryChrysophanol, a naturally occurring anthraquinone compound found in various plants, fungi, and lichens, has garnered increasing attention for its potential therapeutic benefits, particularly in the context of inflammation-related disorders. This review aims to provide a comprehensive overview of the anti-inflammatory properties of chrysophanol and ...
Radhika Singh, Akhil Sharma, Sushma Devi
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No induction of chromosomal aberrations in Chinese hamster ovary cells by chrysophanol
Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2001Chrysophanol is an anthraquinone which occurs in several herbal drugs, e.g. senna, a commonly used laxative. As there are only limited data on its clastogenic potential we have investigated its capability to cause chromosomal aberrations in the Chinese hamster ovary cell assay.
U, Mengs, D, Schuler, R R, Marshall
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UV and IR spectra of anthraquinone and chrysophanol derivatives
Journal of Applied Spectroscopy, 19671. The electronic absorption spectra of nitrogen-containing derivatives of anthraquinone and chrysophanol have an aromatic character. 2. Absorption bands at 2700 and 3200 A are characteristic for the nitrogen-containing derivatives of anthraquinone, whereas an absorption band with a maximum at 4300 A is characteristic for the derivatives
T. K. Chumbalov +2 more
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An efficient total synthesis of chrysophanol and the sennoside C aglycon
Tetrahedron Letters, 2005AbstractFor Abstract see ChemInform Abstract in Full Text.
Nikolai Kuhnert, Hoshiar Y. Molod
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[Determination of chrysophanol in semen Cassiae by HPLC].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2000A HPLC method for the determination of chrysophanol in Semen Cassiae was investigated. The result showed that this method was simple, specific and accurate. The recovery was 99.0% and relative standard deviation was 1.8%. The method is useful for the quality control of this medicinal meaterial.
A, Cao +4 more
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Promotion of Ferroptosis in Oral Cancer Cell Lines by Chrysophanol
Current Topics in Nutraceutical Research, 2019Oral cancer is a type of head and neck cancer that can be life threatening if not diagnosed and treated early. Ferroptosis is a type of programmed or regulated cell death dependent on iron and reactive oxygen species but is a caspase-independent form of non-apoptotic cell death. Therefore, there is a need to identify candidate natural compound that may
Lin Ya-Hsuan +5 more
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Die Stellung der Glucose in synthetisch hergestelltem Chrysophanol‐glucosid
Chemische Berichte, 1966AbstractDie Ansicht Hörhammers, daß die Glucose in synthetischem Chrysophanol‐glucosid in Stellung 1 am Chrysophanolmolekül gebunden ist, können wir nicht teilen. Wiederholung unserer früheren Untersuchung wie auch ein neues Experiment bestätigten, daß der Glucoserest in synthetischem Chrysophanol‐glucosid in Stellung 8 gebunden ist.
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Chrysophanol anthrone: a theoretical study on the potential energy surface
Molecular Simulation, 2016AbstractThe potential energy surface (PES) of chrysophanol anthrone, the active component of Goa Powder, was systematically explored and thoroughly scrutinised via density functional theory, in order to gain an understanding of its physicochemical properties. In particular, we focused on the rotations of the two hydroxyl-phenyl dihedral angles.
Fernando J. Tun-Rosado +4 more
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Chrysophanol and Nepodin Constituents ofSimethis bicolorKnth
International Journal of Crude Drug Research, 1985AbstractFrom roots of Simethis bicolor Kunth, two constituents were isolated: l,8-dihydroxy-3-methyl-anthraquinone (chrysophanol), and 2-acetyl-1,8-dihydroxy-3-methyl naphthalene (nepodin).
I. Cadavid, A. Gato, J. M. Calleja
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