Results 31 to 40 of about 118,118 (316)
NMR solution structure of a chymotrypsin inhibitor from the Taiwan cobra Naja naja atra [PDF]
, 2013 The Taiwan cobra (Naja naja atra) chymotrypsin inhibitor (NACI) consists of 57 amino acids and is related to other Kunitz-type inhibitors such as bovine pancreatic trypsin inhibitor (BPTI) and Bungarus fasciatus fraction IX (BF9), another chymotrypsin ...
Chang, Long-Sen +3 more
core +2 more sources
Frontiers in Chemistry, 2022 Enzyme function can be altered via modification of its amino acid residues, side chains and large-scale domain modifications. Herein, we have addressed the role of residue modification in catalytic activity and molecular recognition of an enzyme alpha ...
Pritam Biswas +13 more
doaj +1 more source
Pharmaceutics, 2022 Till date, different types of conventional drugs have been used to fight tumors. However, they have significant flaws, including their usage being constrained because of their low bioavailability, poor supply, and serious side effects.
Amit Singh +3 more
doaj +1 more source
Enzymatic Pea Protein Hydrolysates Are Active Trypsin and Chymotrypsin Inhibitors
Foods, 2019 In this work, we report the potency of enzymatic hydrolysates of pea proteins against trypsin and chymotrypsin. Pea protein concentrate was digested with each of alcalase, chymotrypsin, pepsin, and trypsin, followed by membrane separation of the protein ...
Temitola Awosika, Rotimi E. Aluko
doaj +1 more source
Obesity and cancer: existing and new hypotheses for a causal connection [PDF]
, 2018 Existing explanations of obesity-associated cancer emphasise direct mutagenic effects of dietary components or hormonal imbalance. Some of these hypotheses are reviewed briefly, but recent evidence suggests a major role for chronic inflammation in cancer
Darlington, L. Gail +2 more
core +2 more sources
The regions of the sequence most exposed to the solvent within the amyloidogenic state of a protein initiate the aggregation process. [PDF]
, 2004 Formation of misfolded aggregates is an essential part of what proteins can do. The process of protein aggregation is central to many human diseases and any aggregating event needs to be prevented within a cell and in protein design.
AMORESANO, ANGELA +6 more
core +1 more source
Frontiers in Oncology, 2020 The Epithelial-Mesenchymal Transition (EMT) is an important concept in understanding the processes of oncogenesis, especially with respect to the relationship between cell proliferation and metastatic properties such as spontaneous cell motility ...
Trevor W. Stone
doaj +1 more source
Studies of α′,β′‐Epoxyketone Synthesis by Small‐Molecule Flavins and Flavoenzymes
Angewandte Chemie, EarlyView.A combined synthetic and biochemical approach links the flavoenzyme EpxF to three key steps in epoxomicin biosynthesis. Crystallography, mutagenesis, and 13C‐labeling complete the mechanistic picture of α′,β′‐epoxyketone formation and illustrate the potential of flavin‐mediated transformations.
Alexandra Walter +5 more
wiley +2 more sources
Marine Drugs, 2013 The Kunitz-type protease inhibitors are the best-characterized family of serine protease inhibitors, probably due to their abundance in several organisms.
Caroline B. F. Mourão +1 more
doaj +1 more source
Zootechnical Parameters and Enzyme Activity in the Species Brycon moorei (Steindachner 1878)
Fishes, 2023 Brycon moorei is an opportunistic omnivorous species. It is not known what its nutritional requirements are at any stage of its development; this study determined the influence of diet on the zootechnical parameters and enzyme activity of these fish.
Carlos David-Ruales +2 more
doaj +1 more source