Results 61 to 70 of about 119,725 (278)
PathogensSerine protease inhibitors (serpins) participate in the regulation of inflammation, blood coagulation, and complement activation in humans. This research aimed to identify and characterize such inhibitors of the human liver fluke Opisthorchis viverrini ...
Rosnanee Salang +3 more
doaj +1 more source
The regions of the sequence most exposed to the solvent within the amyloidogenic state of a protein initiate the aggregation process. [PDF]
, 2004 Formation of misfolded aggregates is an essential part of what proteins can do. The process of protein aggregation is central to many human diseases and any aggregating event needs to be prevented within a cell and in protein design.
AMORESANO, ANGELA +6 more
core +1 more source
IMMOBILIZATION OF CHYMOTRYPSIN ON MAGNETIC FE O NANOPARTICLES
Foods and Raw Materials, 2013 Modern methods of chemical modification of enzymes conferring increased catalytic activity and stability to these molecules have been considered. The advantages of using magnetic nanoparticles for the production of stable immobilized enzyme preparations ...
Dyshlyuk L.S. +2 more
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The Endoplasmic Reticulum Glucosyltransferase Recognizes Nearly Native Glycoprotein Folding Intermediates [PDF]
, 2004 The UDP-Glc:glycoprotein glucosyltransferase (GT), a key player in the endoplasmic reticulum (ER) quality control of glycoprotein folding, only glucosylates glycoproteins displaying non-native conformations.
Caramelo, Julio Javier +3 more
core +1 more source
Journal of Lipid Research, 2012 Upon apoptotic stimuli, lysosomal proteases, including cathepsins and chymotrypsin, are released into cytosol due to lysosomal membrane permeabilization (LMP), where they trigger apoptosis via the lysosomal-mitochondrial pathway of apoptosis. Herein, the
Kai Zhao +7 more
doaj +1 more source
Turkish Journal of Agriculture: Food Science and Technology, 2022 In this study, the potential of sunflower protein hydrolysates to inhibit angiotensin converting enzyme (ACE) and dipeptidyl peptidase-IV (DPP-IV) enzyme was determined.
Şebnem Şimşek
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Principal basis for enzyme power [PDF]
, 2008 The reaction rate enhancement that enzymes produce had not been fully appreciated. The object of the article is to present the mechanism of the enormous catalytic power of the enzymes.
Alexander G. Foigel
core +1 more source
Inhibition of pancreatic cholesterol esterase reduces cholesterol absorption in the hamster [PDF]
, 2004 BACKGROUND: Pancreatic cholesterol esterase has three proposed functions in the intestine: 1) to control the bioavailability of cholesterol from dietary cholesterol esters; 2) to contribute to incorporation of cholesterol into mixed micelles; and 3) to ...
Contos, Linda M +4 more
core +2 more sources
Journal of Biological Chemistry, 2013 Background: Hereditary pancreatitis-associated mutations alter regulation of trypsinogen activation by chymotrypsin C. Results: Activation of mouse trypsinogens T8 and T9 is inhibited by chymotrypsin C-mediated cleavage of the autolysis loop. Conclusion:
B. Németh +3 more
semanticscholar +1 more source
Action of plant proteinase inhibitors on enzymes of physiopathological importance
Anais da Academia Brasileira de Ciências, 2009 Obtained from leguminous seeds, various plant proteins inhibit animal proteinases, including human, and can be considered for the development of compounds with biological activity.
Maria Luiza V. Oliva, Misako U. Sampaio
doaj +1 more source