Results 11 to 20 of about 4,425,847 (185)

Cytokine Induced Killer (CIK) Cells Based Adoptive Immunotherapy [PDF]

open access: yesJournal of Gandaki Medical College, 2018
Cytokine induced killer (CIK) cells has been increasingly used in adoptive immunotherapy against various cancers and viral infections. This review summarizes the basic overview of CIK cells as a therapeutic immunocyte.
S Timalsena, P P Lamichhane
doaj   +4 more sources

CIK Cell Therapy for Solid Tumor [PDF]

open access: yesNano Biomedicine and Engineering, 2014
In recent years, the clinical trials on applying cytokine induced killer (CIK) cells to solid tumor therapy have been launched worldwide. CIK cells are a heterogeneous subset of ex-vivo expanded T lymphocytes, they present a mixed T-NK phenotype and are ...
Jingjing Zhang, Yao Yang, Hualin Fu
doaj   +3 more sources

CD300LG improves the cytotoxic activity of CIK

open access: yesCentral European Journal of Immunology, 2017
To investigate the effect of CD300LG-γ induction on the cytotoxic activity of CIK. Eukaryotic expression plasmid hCD300LG-γ/pEGFP-C3, which can express human CD300LG-γ, was constructed and transfected into CHO cells by lipofectamine.
Qiuyue Wang   +6 more
doaj   +2 more sources

The possible molecular regulation mechanism of CIK cells inhibiting the proliferation of Human Lung Adenocarcinoma NCL-H157 Cells

open access: yesOpen Medicine, 2016
Cytokine-induced killer (CIK) cells were isolated and proliferation from human peripheral blood and cultured in appropriate growth medium. The biological characteristics of CIK cells were further determined by the characterization of surface markers by ...
Li Dengrui   +7 more
doaj   +2 more sources

Biological Character of RetroNectin Activated Cytokine-Induced Killer Cells [PDF]

open access: yesJournal of Immunology Research, 2016
Adoptive cell therapy (ACT) using autologous cytokine-induced killer (CIK) cells is a promising treatment for metastatic carcinomas. In this study, we investigated the impact of RetroNectin on the proliferation, phenotype alternation, cytokine secretion,
Lu Han   +3 more
doaj   +2 more sources

Cytokines for the induction of antitumor effectors: The paradigm of Cytokine-Induced Killer (CIK) cells [PDF]

open access: yesCytokine & Growth Factor Reviews, 2017
Cytokine-Induced killer (CIK) cells are raising growing interest in cellular antitumor therapy, as they can be easily expanded with a straightforward and inexpensive protocol, and are safe requiring only GMP-grade cytokines to obtain very high amounts of cytotoxic cells. CIK cells do not need antigen-specific stimuli to be activated and proliferate, as
CAPPUZZELLO, ELISA   +3 more
openaire   +4 more sources

Stimulation of DC-CIK with PADI4 Protein Can Significantly Elevate the Therapeutic Efficiency in Esophageal Cancer

open access: yesJournal of Immunology Research, 2019
Background. PADI4 has extensive expression in many tumors. This study applied PADI4 as a tumor marker to stimulate DC- (dendritic cell-) CIK (cytokine-induced killer), an immunotherapy approach. Methods. A PADI4 expression plasmid was transfected into EC-
Chunyan Liu   +6 more
doaj   +2 more sources

Cytotoxic capacity of IL-15-stimulated cytokine-induced killer cells against human acute myeloid leukemia and rhabdomyosarcoma in humanized preclinical mouse models [PDF]

open access: yesFrontiers in Oncology, 2012
Allogeneic stem cell transplantation (allo-SCT) has become an important treatment modality for patients with high risk acute myeloid leukemia (AML) and is also under investigation for soft tissue sarcomas.
Eva eRettinger   +11 more
doaj   +2 more sources

Growth of Human Colorectal Cancer SW1116 Cells Is Inhibited by Cytokine-Induced Killer Cells [PDF]

open access: yesClinical and Developmental Immunology, 2011
Previous reports have suggested that treatment with cytokine-induced killer (CIK) cells may benefit patients with various types of tumor. The aim of this study was to evaluate the antitumor effects of CIK cells against the colorectal cancer line SW1116 ...
Yao Wang   +6 more
doaj   +2 more sources

Advancing CIK cell immunotherapy: highlights from the second international conference on DC-CIK and CAR-CIK approaches

open access: yesCancer Immunology, Immunotherapy
On April 7, 2025, the 2nd International CIK Cell Conference was held in Monza, Italy, marking the establishment of the International Society for CIK Cells (ISCC).
Amit Sharma   +11 more
doaj   +6 more sources

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