Results 101 to 110 of about 11,577 (216)
Cigarette smoke exposure impairs respiratory epithelial ciliogenesis [PDF]
, 2009 Background: Cigarette smoke exposure is considered an important negative prognostic factor for chronic rhinosinusitis (CRS) patients. However, there is no clear mechanistic evidence implicating cigarette smoke exposure in the poor clinical evolution of ...
COHEN, Noam A. +11 more
core +1 more source
Aggregate, Volume 7, Issue 6, June 2026.This review surveys eukaryotic cilia as putative quantum‐enabled sensory and regulatory centers. It highlights their multifaceted roles in the cell, focuses on the nontrivial roles of quantum mechanics in their membrane and cytoskeletal proteins, and introduces the essential building blocks enabling quantum properties to survive in the warm, wet, and ...
Daniel L. Bilezikian +5 more
wiley +1 more source
The HOPS Complex Subunit VPS39 controls ciliogenesis through autophagy [PDF]
, 2020 Primary cilia are microtubule-based organelles that assemble and protrude from the surface of most mammalian cells during quiescence. The biomedical relevance of cilia is indicated by disorders ascribed to cilia dysfunction, known as ciliopathies, that ...
Crina, Claudia +5 more
core +1 more source
American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1286-1305, June 2026.ABSTRACT Bladder exstrophy and epispadias complex (BEEC) is one of the most severe congenital malformations of the urogenital tract, significantly impacting continence, sexual function, and renal function. To date, the only recurrent genetic aberration identified is the 22q.11.2 microduplication, but several candidate regions and genes including ...
Agneta Nordenskjöld +9 more
wiley +1 more source
The daughter centriole controls ciliogenesis by regulating Neurl-4 localization at the centrosome [PDF]
, 2017 The two centrioles of the centrosome differ in age and function. Although the mother centriole mediates most centrosome-dependent processes, the role of the daughter remains poorly understood.
Sütterlin, Christine +5 more
core +1 more source
Targeting Primary Ciliogenesis with Small-Molecule Inhibitors [PDF]
, 2020 International audienceThe primary cilium is generally a non-motile solitary organelle that protrudes from a basal body at the cell surface in various cell types in multicellular organisms.
Guen, Vincent J, Prigent, Claude
core +1 more source
Nature Communications, 2018 Ciliogenesis is negatively regulated by the CP110-CEP97 complex, although the mechanism controlling mother centriole localization is poorly understood. Here, Huang et al.
Ning Huang +6 more
doaj +1 more source
Cell Reports, 2017 Mutations in CEP290, a transition zone protein in primary cilia, cause diverse ciliopathies, including Leber congenital amaurosis (LCA) and Joubert-syndrome and related disorders (JSRD).
Hiroko Shimada +14 more
doaj +1 more source
American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1179-1191, June 2026.ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson +1 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 6, June 2026.The phosphorylated protein profiles of the longissimus dorsi muscle tissues of Xinjiang brown cattle and Kazakh cattle were analyzed. RAB12 was a differentially expressed phosphorylated protein. After knockdown of RAB12, the immunofluorescence intensity of MYHC significantly increased, promoting myoblast differentiation.
Ailifeire Wumaier +9 more
wiley +1 more source