Results 81 to 90 of about 12,764 (170)
ELECTRON MICROSCOPICAL OBSERVATIONS ON THE TRACHEAL EPITHELIUM OF THE ONE-HUMPED CAMEL (CAMELUS DROMEDARIUS) WITH SPECIAL REFERENCE TO CILIOGENESIS [PDF]
Assiut Veterinary Medical Journal, 1999 This study was carried out on 10 adult, apparently healthy one-humped camels of different ages and of both sexes. The ultrastructure of camel tracheal epithelium was studied by scanning and transmission electron microscopes.
Yousria A. Abd El-Rahman
doaj +1 more source
Aging Cell, Volume 25, Issue 11, November 2026.Aging‐associated NAD+ depletion in hypothalamic neurons shortens primary cilia and disrupts CHMP4B trafficking to lysosomes during lysosomal stress, leading to impaired TRPML1–mediated Ca2+ signaling and lysosomal stress responses. Calorie restriction restores hypothalamic NAD+ levels, ciliary structure, and lysosomal homeostasis, thereby improving ...
Se Eun Park +15 more
wiley +1 more source
Cells, 2020 Ciliopathies are a group of human genetic disorders associated with mutations that give rise to the dysfunction of primary cilia. Ciliogenesis-associated kinase 1 (CILK1), formerly known as intestinal cell kinase (ICK), is a conserved serine and ...
Eric J. Wang +3 more
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Liver International, Volume 46, Issue 11, November 2026.ABSTRACT Background & Aims Laterality disorders are rare congenital conditions caused by disruption of left–right embryonic patterning, often associated with ciliary dysfunction. Despite the identification of numerous causative genes, the molecular basis remains unresolved in many patients.
Alina Kurolap +19 more
wiley +1 more source
Spectrin-based membrane skeleton supports ciliogenesis
, 2019 Cilia are remarkable cellular devices that power cell motility and transduce extracellular signals. To assemble a cilium, a cylindrical array of 9 doublet microtubules push out an extension of the plasma membrane.
Zhongyun Xie +25 more
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Animal Genetics, Volume 57, Issue 5, October 2026.ABSTRACT Environmental stressors in commercial poultry systems can negatively affect bird welfare, although individuals vary considerably in their responses. Neuroplasticity within the hippocampus, measured through the density of doublecortin‐positive (DCX+) neurons, provides a potential biomarker of stress experience in laying hens.
Lindsay Neuert +8 more
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Dysfunction of GSK3β disrupts ciliogenesis.
, 2015 (A) Schematic model of the acquisition of synchronized mitosis–G0 phase NIH 3T3 cells, treated with double thymidine block, nocodazole (Noc), and the indicated GSK3 inhibitors. (B and C) Inhibition of GSK3 impairs ciliogenesis.
Tingting Zhang (264633) +6 more
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Cell Reports, 2017 Mutations in CEP290, a transition zone protein in primary cilia, cause diverse ciliopathies, including Leber congenital amaurosis (LCA) and Joubert-syndrome and related disorders (JSRD).
Hiroko Shimada +14 more
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Streamlining Diagnosis of Bardet–Biedl Syndrome: New Diagnostic Algorithm With Updated Criteria
American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2181-2198, October 2026.ABSTRACT Considerable advances have been made in our understanding of Bardet–Biedl syndrome (BBS), particularly in its core clinical features and molecular genetics, warranting an update to the existing diagnostic criteria framework. Using a rigorous, evidence‐based, and consensus‐driven process, a multidisciplinary group of international experts and ...
Jeremy J. Pomeroy +16 more
wiley +1 more source
Cell Biochemistry and Function, Volume 44, Issue 10, October 2026.ABSTRACT PDE4DIP/Myomegalin was originally identified as a Golgi‐ and centrosome‐associated protein that interacts with phosphodiesterase 4D, but subsequent work has placed it within a broader network of organelle‐associated signaling and cytoskeletal regulation.
Cong Wang +3 more
wiley +1 more source