Results 71 to 80 of about 12,764 (170)

BCAP is a centriolar satellite protein and inhibitor of ciliogenesis [PDF]

, 2017
The centrosome and cilium are organelles with important roles in microtubule organisation, cell division, cell signalling, embryogenesis, and tissue homeostasis. The two organelles are mutually exclusive.
Murdoch, Jennifer, Christopher J. Wilkinson, Iqbal, Anila, Wilkinson, Christopher, De Saram, Paulu, Anila Iqbal, Jennifer N. Murdoch, Paul de Saram   +7 more
core   +1 more source

Epigenetic signatures of attention problems in youth with childhood exposure to family and community violence

Psychiatry and Clinical Neurosciences, EarlyView.
Aim The link between violence‐related epigenetic changes and attentional problems (APs) is still not well understood. This article examines if exposure to family and community violence during childhood and adolescence may shape DNA methylation patterns associated with attention in youth.
Renata Queiroz Ramos, Adriane Feijó Evangelista, Cosme Marcelo Furtado Passos da Silva, Fernanda Serpeloni, Joviana Quintes Avanci, Natasha Reis Lacerda, Simone Gonçalves de Assis   +6 more
wiley   +1 more source

Motile ciliogenesis and the mitotic prism

, 2019
International audienceMotile cilia of epithelial multiciliated cells transport vital fluids along organ lumens to promote essential respiratory, reproductive and brain functions.
Meunier, Alice, Adel Al Jord, Al Jord, Adel, Alice Meunier, Spassky, Nathalie, Nathalie Spassky   +5 more
core   +1 more source

TMEM16A Ca2+‐activated Cl− channel: Functional interactions with cytoskeletal and membrane‐associated proteins

The Journal of Physiology, EarlyView.
Abstract figure legend The calcium‐activated chloride (ClCa) channel TMEM16A (also known as ANO1) plays critical roles in ion transport, neurotransmission and smooth muscle contraction. Dysregulation of TMEM16A channel activity contributes to the development and progression of various diseases.
Hisao Yamamura, Rubii Kondo, Yoshiaki Suzuki, Yuji Imaizumi, Aya Yamamura   +4 more
wiley   +1 more source

Chlamydomonas as a model system to study cilia and flagella using genetics, biochemistry, and microscopy

Frontiers in Cell and Developmental Biology
The unicellular green alga, Chlamydomonas reinhardtii, has played a central role in discovering much of what is currently known about the composition, assembly, and function of cilia and flagella.
Wallace F. Marshall
doaj   +1 more source

Loss of MACF1 Abolishes Ciliogenesis and Disrupts Apicobasal Polarity Establishment in the Retina

Cell Reports, 2016
Summary: Microtubule actin crosslinking factor 1 (MACF1) plays a role in the coordination of microtubules and actin in multiple cellular processes. Here, we show that MACF1 is also critical for ciliogenesis in multiple cell types.
Helen L. May-Simera, Jessica D. Gumerson, Chun Gao, Maria Campos, Stephanie M. Cologna, Tina Beyer, Karsten Boldt, Koray D. Kaya, Nisha Patel, Friedrich Kretschmer, Matthew W. Kelley, Ronald S. Petralia, Megan G. Davey, Tiansen Li   +13 more
doaj   +1 more source

Ciliogenesis is reciprocally regulated by PPARA and NR1H4/FXR through controlling autophagy in vitro and in vivo

, 2018
The primary cilia are evolutionarily conserved microtubule-based cellular organelles that perceive metabolic status and thus link the sensory system to cellular signaling pathways.
Goo Taeg Oh (581951), Kyunghee Byun (162379), Yunash Maharjan (5233262), Seong-Kyu Choe (256094), Zhi-qiang Liu (1364745), Raekil Park (224445), Jae-Young Lim (519753), Raghbendra Kumar Dutta (5233265), SeongAe Kwak (5233268), Joon No Lee (5233271), Myeongjoo Son (618788)   +10 more
core   +3 more sources

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation

, 2021
Primary cilia are nonmotile cellular signal-sensing antenna-like structures composed of microtubule-based structures that distinguish them from motile cilia in structure and function. Primary ciliogenesis is regulated by various cellular signals, such as
Kyung Ho Lee, Bo Yeon Kim, Sun-Ok Kim, Kyoung Sang Cho   +3 more
core   +1 more source

Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis

eLife, 2016
Upon cell cycle exit, centriole-to-basal body transition facilitates cilia formation. The centriolar protein Cp110 is a regulator of this process and cilia inhibitor, but its positive roles in ciliogenesis remain poorly understood.
Peter Walentek, Ian K Quigley, Dingyuan I Sun, Umeet K Sajjan, Christopher Kintner, Richard M Harland   +5 more
doaj   +1 more source