Results 71 to 80 of about 9,240 (177)
ELECTRON MICROSCOPICAL OBSERVATIONS ON THE TRACHEAL EPITHELIUM OF THE ONE-HUMPED CAMEL (CAMELUS DROMEDARIUS) WITH SPECIAL REFERENCE TO CILIOGENESIS [PDF]
This study was carried out on 10 adult, apparently healthy one-humped camels of different ages and of both sexes. The ultrastructure of camel tracheal epithelium was studied by scanning and transmission electron microscopes.
Yousria A. Abd El-Rahman
doaj +1 more source
Ciliopathies are a group of human genetic disorders associated with mutations that give rise to the dysfunction of primary cilia. Ciliogenesis-associated kinase 1 (CILK1), formerly known as intestinal cell kinase (ICK), is a conserved serine and ...
Eric J. Wang +3 more
doaj +1 more source
The identification of a patient carrying a novel homozygous p.(Gln206Ter) POC5 variant revealed a metabolic phenotype associated with POC5 deficiency. POC5 deficiency disrupts centriolar architecture and ciliary organization, leading to impaired proliferation, premature cellular senescence, and reduced insulin signaling.
Valeria Pistorio +10 more
wiley +1 more source
The role of SDCCAG3 in ciliogenesis
Endosomal trafficking is an important process for multiple cell function. The serologically defined colon cancer antigen-3 (SDCCAG3) is a novel endosomal protein localized at early and recycling endosomes. However, its detail function is not well-known. In this thesis, I investigated the role of SDCCAG3 in ciliogenesis and Fas-mediated apoptosis.
openaire +2 more sources
Upon cell cycle exit, centriole-to-basal body transition facilitates cilia formation. The centriolar protein Cp110 is a regulator of this process and cilia inhibitor, but its positive roles in ciliogenesis remain poorly understood.
Peter Walentek +5 more
doaj +1 more source
ABSTRACT Pulmonary hypertension (PH) is a frequent complication of interstitial lung diseases (ILD) that worsens morbidity and mortality. Cigarette smoking has a detrimental effect on transplant‐free survival of patients with ILD, including patients with idiopathic pulmonary fibrosis (IPF).
Iryna Zhyvylo +7 more
wiley +1 more source
Ciliogenesis is negatively regulated by the CP110-CEP97 complex, although the mechanism controlling mother centriole localization is poorly understood. Here, Huang et al.
Ning Huang +6 more
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Suppression of Ciliogenesis Alleviates Cellular Senescence via AKT Signaling in Gingival Aging
In human gingival aging, aged gingival fibroblasts show increased senescence with enhanced primary cilia formation. Targeting cilia formation by knocking down IFT88 could reverse fibroblast senescence via the AKT signaling and alleviate periodontal inflammation.
Wenjun Shao +9 more
wiley +1 more source
Mutations in CEP290, a transition zone protein in primary cilia, cause diverse ciliopathies, including Leber congenital amaurosis (LCA) and Joubert-syndrome and related disorders (JSRD).
Hiroko Shimada +14 more
doaj +1 more source

