Results 191 to 200 of about 41,549 (330)

Primary cilia function as hubs for signal transduction. [PDF]

Cell Biosci
Li B, He YY, Yang ZM.
europepmc   +1 more source

Primary cilium mechanotransduction of tensile strain in 3D culture: Finite element analyses of strain amplification caused by tensile strain applied to a primary cilium embedded in a collagen matrix

, 2014
Pattie S. Mathieu, Josephine C. Bodle, Elizabeth G. Loboa   +2 more
openalex   +1 more source

Identification of novel genes regulating the development of the palate

Developmental Dynamics, EarlyView.
Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley   +1 more source

Phosphatidylinositol 4,5-bisphosphate impacts extracellular vesicle shedding from C. elegans ciliated sensory neurons. [PDF]

J Cell Sci
Elsayyid MW, Semmel AE, Parekh KD, Prova NS, Ke T, Tanis JE.   +5 more
europepmc   +1 more source

Super-resolution Molecular Map of Basal Foot Reveals Novel Cilium in Airway Multiciliated Cells [PDF]

, 2018
Quynh Nguyen, Zhen Liu, Rashmi Nanjundappa, Alexandre Megherbi, Nathalie Delgehyr, Hong Ouyang, Lorna Zlock, Étienne Coyaud, Estelle Laurent, Sharon Dell, Walter E. Finkbeiner, Theo J. Moraes, Brian Raught, Kirk J. Czymmek, Alice Munier, Moe R. Mahjoub, Vito Mennella   +16 more
openalex   +1 more source

Loss of Twist1 leads to disruption of ciliary length, endocytic vesicle dynamics, and cell–cell junctions during neural tube formation

Developmental Dynamics, EarlyView.
Abstract Background Endocytosis constitutes a fundamental cellular process governing development through coordinated regulation of plasma membrane remodeling and ciliogenesis, processes essential for cell shape changes and tissue development. Although Twist1 null embryos display complete cranial neural tube (NT) closure defects and conditional knockout
Derrick Thomas, Brittany M. Hufft‐Martinez, Zarna Lalwani, Vi Pham, Mary Elmeniawi, An J. Tran, Jianming Xu, Irfan Saadi, Walid D. Fakhouri   +8 more
wiley   +1 more source

New Insights into the Molecular Actions of Grosheimin, Costunolide, and α- and β-Cyclocostunolide on Primary Cilia Structure and Hedgehog Signaling. [PDF]

Int J Mol Sci
Murillo-Pineda M, Martínez-Miralles J, Medina-Calzada Z, Varela RM, Macías FA, Chinchilla N, Juárez-Soto Á, Santpere G, Reales E.   +8 more
europepmc   +1 more source

A novel role for Rab23 in the trafficking of Kif17 to the primary cilium [PDF]

, 2015
Yi Shan Lim, Bor Luen Tang
openalex   +1 more source

Sex‐specific elevated incidence of glaucoma associated with topiramate versus valproate or lamotrigine in epilepsy, not migraine: A population‐based cohort study

Epilepsia, EarlyView.
Abstract Objective Topiramate has been linked to increased glaucoma risk, potentially through mechanisms involving ocular fluid shifts. However, comparative risks vs other antiseizure medications (ASMs) and variation by sex or indication remain uncertain.
Cuiling Wei, Rachel Yui Ki Chu, Rachel Lancey Lai, Florinda Hui‐Ning Chu, Ian Yu Hin Leung, William Chun Yin Leung, Franco Wing Tak Cheng, Thomas Chi Ho Lam, Ian Chi Kei Wong, Esther Wai Yin Chan, Francisco Tsz Tsun Lai   +10 more
wiley   +1 more source

A protein complex in the extreme distal tip of vertebrate motile cilia controls their organization, length, and function. [PDF]

Nat Commun
Hong J, Lee C, Madhu G, Papoulas O, Atayeter E, Hoogerbrugge G, Pan J, Takagishi M, Manzi NI, Dickinson DJ, Horani A, Brody SL, Marcotte EM, Prakash VN, Park TJ, Wallingford JB.   +15 more
europepmc   +1 more source