Results 51 to 60 of about 36,064 (332)

The small GTPase Rab29 is a common regulator of immune synapse assembly and ciliogenesis [PDF]

, 2015
Acknowledgements We wish to thank Jorge Galán, Gregory Pazour, Derek Toomre, Giuliano Callaini, Joel Rosenbaum, Alessandra Boletta and Francesco Blasi for generously providing reagents and for productive discussions, and Sonia Grassini for technical ...
A Batista, A Onnis, AC Smith, AH Hutagalung, AL Kullas, AW van der Velden, BT Keady, C Cassioli, C Geisler, C Margadant, C T Baldari, C Wasmeier, CJ Westlake, CP Horgan, DA MacLeod, DS Gomez, E Schonteich, EM Manders, F Finetti, F Finetti, F Finetti, G Bonello, G Iezzi, G Patino-Lopez, GJ Pazour, H Soares, I Jordens, JA Follit, JC Stinchcombe, JK Chen, K Geddes, L Patrussi, L Patrussi, LB Pedersen, LI Ehrlich, M de la Roche, M Esquerré, M Gottardo, M Kurowska, MV Nachury, N Capitani, NB Martín-Cófreces, RS Kalupahana, S Pacini, S Spanò, S Spanò, S Spanò, S Wang, SR McGlashan, SY Wong, V Das, VM Wu   +51 more
core   +1 more source

Farnesylation of the Transducin G Protein Gamma Subunit Is a Prerequisite for Its Ciliary Targeting in Rod Photoreceptors

Frontiers in Molecular Neuroscience, 2018
Primary cilia are microtubule-based organelles, which protrude from the plasma membrane and receive a wide range of extracellular signals. Various cilia use G protein-coupled receptors (GPCRs) for the detection of these signals.
Celine Brooks, Joseph Murphy, Marycharmain Belcastro, Daniel Heller, Saravanan Kolandaivelu, Oleg Kisselev, Maxim Sokolov, Maxim Sokolov   +7 more
doaj   +1 more source

A novel defined cuproptosis-related gene signature for predicting the prognosis of lung adenocarcinoma

Frontiers in Genetics, 2022
Lung adenocarcinoma (LUAD) has become the most prevalent histologic subset of primary lung cancer, and effective innovative prognostic models are needed to enhance the feasibility of targeted therapies for the disease.
Huizhe Zhang, Yanchen Shi, Qing Yi, Cong Wang, Qingqing Xia, Yufeng Zhang, Weilong Jiang, Jia Qi   +7 more
doaj   +1 more source

Design and Fabrication of an Integrated Hollow Concave Cilium MEMS Cardiac Sound Sensor

Micromachines, 2022
In light of a need for low-frequency, high sensitivity and broadband cardiac murmur signal detection, the present work puts forward an integrated MEMS-based heart sound sensor with a hollow concave ciliary micro-structure. The advantages of a hollow MEMS
Bo Wang, Pengcheng Shi, Yuhua Yang, Jiangong Cui, Guojun Zhang, Renxin Wang, Wendong Zhang, Changde He, Yirui Li, Shuotong Wang   +9 more
doaj   +1 more source

Chronic Hypobaric Hypoxia Modulates Primary Cilia Differently in Adult and Fetal Ovine Kidneys

Frontiers in Physiology, 2017
Hypoxic environments at high altitude have significant effects on kidney injury. Following injury, renal primary cilia display length alterations. Primary cilia are mechanosensory organelles that regulate tubular architecture.
Kiumars Shamloo, Juan Chen, Jasmine Sardar, Rinzhin T. Sherpa, Rajasekharreddy Pala, Kimberly F. Atkinson, William J. Pearce, Lubo Zhang, Surya M. Nauli, Surya M. Nauli   +9 more
doaj   +1 more source

Design and Implementation of a Composite Hydrophone of Sound Pressure and Sound Pressure Gradient

Micromachines, 2021
The bionic cilium MEMS vector hydrophone has the characteristics of low power consumption, small volume, and good low-frequency response. Nevertheless, there exists the problem of left–right ambiguity in the azimuth estimation of a single hydrophone.
Guojun Zhang, Lansheng Zhang, Songxiang Ji, Xi Yang, Renxin Wang, Wendong Zhang, Shie Yang   +6 more
doaj   +1 more source

A role for Tctex-1 (DYNLT1) in controlling primary cilium length [PDF]

, 2011
The microtubule motor complex cytoplasmic dynein is known to be involved in multiple processes including endomembrane organization and trafficking, mitosis, and microtubule organization.
MacCarthy-Morrogh, LJ, Miss Nicola, Smyllie, Palmer, KJ, Stephens, DJ   +3 more
core   +1 more source

Emerging Roles of Primary Cilia in Glioma

Frontiers in Cellular Neuroscience, 2019
Primary cilia are microtubule-based organelles that are typically present on cells during the G0 or G1-S/G2 phases of the cell cycle. Recent studies of glioblastoma (GBM) biopsies, a brain tumor that is notorious for its aggressive growth and resistance ...
Matthew R. Sarkisian, Matthew R. Sarkisian, Susan L. Semple-Rowland   +2 more
doaj   +1 more source

Ciliary Dyneins and Dynein Related Ciliopathies

Cells, 2021
Although ubiquitously present, the relevance of cilia for vertebrate development and health has long been underrated. However, the aberration or dysfunction of ciliary structures or components results in a large heterogeneous group of disorders in ...
Dinu Antony, Han G. Brunner, Miriam Schmidts   +2 more
doaj   +1 more source

The primary cilium influences interleukin-1 beta-induced NF kappa B signalling by regulating IKK activity [PDF]

, 2014
The primary cilium is an organelle acting as a master regulator of cellular signalling. We have previously shown that disruption of primary cilia assembly, through targeting intraflagellar transport, is associated with muted nitric oxide and ...
A.K.T. Wann, Acunzo, Alford, Amin, Amin, Baeuerle, Baeuerle, Baeuerle, Besschetnova, Boehm, Bracken, Cheong, Clement, Corbit, Corbit, Crepieux, Crowe, DiDonato, Dodd, Dossumbekova, Gao, Gerdes, Griscavage, Hatakeyama, Haycraft, Hoffmann, Huber, J.P. Chapple, Jones, Jones, Kammanadiminti, Karsdal, Lambrecht, Lancaster, Lattke, M.M. Knight, Martel-Pelletier, McGlashan, McMurray, Nauli, Oeckinghaus, Parcellier, Park, Pearle, Plummer, Rohatgi, Saklatvala, Saklatvala, Schmidts, Schneider, Shim, Shiota, Simons, Smith, Takaki, Taulman, Tazawa, Tran, Vezina, Wann, Wann, Wann, Werner, Whitfield, Williams, Windheim, Wu, Zhao, Zhu   +68 more
core   +1 more source