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Circadian clocks: It's time for chronobiology. [PDF]
PLoS Biology, 2023 Circadian clocks are everywhere, yet we still have not translated the vast knowledge gained in the past 20 years on the properties of circadian clocks into practical applications.
Martha Merrow
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Roles of circadian clocks in cancer pathogenesis and treatment. [PDF]
Exp Mol Med, 2021 Circadian clocks are ubiquitous timing mechanisms that generate approximately 24-h rhythms in cellular and bodily functions across nearly all living species.
Lee Y.
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Circadian clocks of the kidney: function, mechanism, and regulation.
Physiol Rev, 2022 An intrinsic cellular circadian clock is located in nearly every cell of the body. The peripheral circadian clocks within the cells of the kidney contribute to the regulation of a variety of renal processes. In this review, we summarize what is currently
Costello HM +4 more
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Interconnections between circadian clocks and metabolism. [PDF]
J Clin Invest, 2021 Circadian rhythms evolved through adaptation to daily light/dark changes in the environment; they are believed to be regulated by the core circadian clock interlocking feedback loop.
Guan D, Lazar MA.
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Circadian clocks guide dendritic cells into skin lymphatics. [PDF]
Nat Immunol, 2021 Migration of leukocytes from the skin to lymph nodes (LNs) via afferent lymphatic vessels (LVs) is pivotal for adaptive immune responses1,2. Circadian rhythms have emerged as important regulators of leukocyte trafficking to LNs via the blood3,4. Here, we
Holtkamp SJ +22 more
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Reciprocal Interactions between Circadian Clocks, Food Intake, and Energy Metabolism [PDF]
Biology, 2023 Like other biological functions, food intake and energy metabolism display daily rhythms controlled by the circadian timing system that comprises a main circadian clock and numerous secondary clocks in the brain and peripheral tissues.
Emma Grosjean +2 more
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Circadian Clocks and Metabolism [PDF]
, 2013 Circadian clocks maintain periodicity in internal cycles of behavior, physiology, and metabolism, enabling organisms to anticipate the 24-h rotation of the Earth. In mammals, circadian integration of metabolic systems optimizes energy harvesting and utilization across the light/dark cycle.
Biliana Marcheva +5 more
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Circadian Clocks, Stress, and Immunity [PDF]
Frontiers in Endocrinology, 2016 In mammals, molecular circadian clocks are present in most cells of the body, and this circadian network plays an important role in synchronizing physiological processes and behaviors to the appropriate time of day.
R. Dumbell, Olga Matveeva, H. Oster
semanticscholar +4 more sources
Keeping time in the dark: Potato diel and circadian rhythmic gene expression reveals tissue‐specific circadian clocks [PDF]
Plant Direct, 2022 The circadian clock is an internal molecular oscillator and coordinates numerous physiological processes through regulation of molecular pathways. Tissue‐specific clocks connected by mobile signals have previously been found to run at different speeds in
Genevieve M. Hoopes +7 more
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Hundreds of LncRNAs Display Circadian Rhythmicity in Zebrafish Larvae
Cells, 2021 Long noncoding RNAs (lncRNAs) have been shown to play crucial roles in various life processes, including circadian rhythms. Although next generation sequencing technologies have facilitated faster profiling of lncRNAs, the resulting datasets require ...
Shital Kumar Mishra +2 more
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