Results 91 to 100 of about 336,986 (421)
A miR-219-5p-bmal1b negative feedback loop contributes to circadian regulation in zebrafish
Communications BiologyMicroRNAs post-transcriptionally regulate gene expression and contribute to numerous life processes, including circadian rhythms. However, whether miRNAs contribute to zebrafish circadian regulation has not yet been investigated.
Lianxin Wu +3 more
doaj +1 more source
Waveforms of molecular oscillations reveal circadian timekeeping mechanisms [PDF]
Commun. Biol. 1, 207 (2018), 2018 Circadian clocks play a pivotal role in orchestrating numerous physiological and developmental events. Waveform shapes of the oscillations of protein abundances can be informative about the underlying biochemical processes of circadian clocks. We derive a mathematical framework where waveforms do reveal hidden biochemical mechanisms of circadian ...
arxiv +1 more source
Claustrum Volume Is Reduced in Multiple Sclerosis and Predicts Disability
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The claustrum is a small, thin structure of predominantly gray matter with broad connectivity and enigmatic function. Little is known regarding the impact of claustrum pathology in multiple sclerosis (MS). Methods This study assessed whether claustrum volume was reduced in MS and whether reductions were associated with specific ...
Nicole Shelley +5 more
wiley +1 more source
Food as circadian time cue for appetitive behavior [version 1; peer review: 5 approved]
F1000Research, 2020 Feeding schedules entrain circadian clocks in multiple brain regions and most peripheral organs and tissues, thereby synchronizing daily rhythms of foraging behavior and physiology with times of day when food is most likely to be found.
Ralph E. Mistlberger
doaj +1 more source
Heterogeneous expression of the core circadian clock proteins among neuronal cell types in mouse retina. [PDF]
PLoS ONE, 2012 Circadian rhythms in metabolism, physiology, and behavior originate from cell-autonomous circadian clocks located in many organs and structures throughout the body and that share a common molecular mechanism based on the clock genes and their protein ...
Xiaoqin Liu +2 more
doaj +1 more source
On the robustness of the in vivo cyanobacterial circadian clock [PDF]
arXiv, 2022 We propose a revisited version of the in vivo model of the cyanobacterial circadian clock. Our aim is to address the lack of robustness predicted for the mutant cyanobacteria without transcriptional regulation of the original model. For this, we rely on an in vitro model of the clock describing explicitly the hexameric structure of the core protein of ...
arxiv
Circadian Rhythms of Crawling and Swimming in the Nudibranch Mollusc Melibe leonina [PDF]
, 2014 Daily rhythms of activity driven by circadian clocks are expressed by many organisms, including molluscs. We initiated this study, with the nudibranch Melibe leonina, with four goals in mind: (1) determine which behaviors are expressed with a daily ...
Kirouac, Lauren E. +3 more
core +2 more sources
Cell, 2017 Most creatures on this planet possess an ability to anticipate upcoming events in the environment, courtesy of their circadian clocks. This allows them to prepare for those changes instead of being caught by surprise, which could mean the difference between life and death. In this SnapShot, we describe the basics of how the clock ticks.
Dragana Rogulja, Bryan J. Song
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Quantitative markers of cortical excitability may help identify responders to anti‐seizure medications (ASMs). We studied the relationship between ASM load and two electroencephalography (EEG) markers of cortical excitability in people with refractory epilepsy. Methods We included individuals with refractory focal epilepsy undergoing
Silvano R. Gefferie +7 more
wiley +1 more source
Splice variants of DOMINO control Drosophila circadian behavior and pacemaker neuron maintenance. [PDF]
, 2019 Circadian clocks control daily rhythms in behavior and physiology. In Drosophila, the small ventral lateral neurons (sLNvs) expressing PIGMENT DISPERSING FACTOR (PDF) are the master pacemaker neurons generating locomotor rhythms.
Cai, Yao +8 more
core +1 more source