Results 21 to 30 of about 336,986 (421)
Circadian clocks of the kidney: function, mechanism, and regulation.
Physiol Rev, 2022 An intrinsic cellular circadian clock is located in nearly every cell of the body. The peripheral circadian clocks within the cells of the kidney contribute to the regulation of a variety of renal processes. In this review, we summarize what is currently
Costello HM +4 more
europepmc +2 more sources
Interconnections between circadian clocks and metabolism. [PDF]
J Clin Invest, 2021 Circadian rhythms evolved through adaptation to daily light/dark changes in the environment; they are believed to be regulated by the core circadian clock interlocking feedback loop.
Guan D, Lazar MA.
europepmc +2 more sources
Circadian clocks guide dendritic cells into skin lymphatics. [PDF]
Nat Immunol, 2021 Migration of leukocytes from the skin to lymph nodes (LNs) via afferent lymphatic vessels (LVs) is pivotal for adaptive immune responses1,2. Circadian rhythms have emerged as important regulators of leukocyte trafficking to LNs via the blood3,4. Here, we
Holtkamp SJ +22 more
europepmc +2 more sources
Hundreds of LncRNAs Display Circadian Rhythmicity in Zebrafish Larvae
Cells, 2021 Long noncoding RNAs (lncRNAs) have been shown to play crucial roles in various life processes, including circadian rhythms. Although next generation sequencing technologies have facilitated faster profiling of lncRNAs, the resulting datasets require ...
Shital Kumar Mishra +2 more
doaj +1 more source
Computational Analysis Predicts Hundreds of Coding lncRNAs in Zebrafish
Biology, 2021 Recent studies have demonstrated that numerous long noncoding RNAs (ncRNAs having more than 200 nucleotide base pairs (lncRNAs)) actually encode functional micropeptides, which likely represents the next regulatory biology frontier.
Shital Kumar Mishra, Han Wang
doaj +1 more source
Real time, in vivo measurement of neuronal and peripheral clocks in Drosophila melanogaster
eLife, 2022 Circadian clocks are highly conserved transcriptional regulators that control ~24 hr oscillations in gene expression, physiological function, and behavior.
Peter S Johnstone +6 more
doaj +1 more source
Keeping time in the dark: Potato diel and circadian rhythmic gene expression reveals tissue-specific circadian clocks. [PDF]
Plant Direct, 2022 The circadian clock is an internal molecular oscillator and coordinates numerous physiological processes through regulation of molecular pathways. Tissue‐specific clocks connected by mobile signals have previously been found to run at different speeds in
Hoopes GM +7 more
europepmc +2 more sources
Communicating clocks shape circadian homeostasis
Science, 2021 Regulating multiple body clocks Circadian rhythms that affect multiple tissues and organ systems are aligned with the dark-light cycle and other external inputs such as feeding.
K. Koronowski, P. Sassone-Corsi
semanticscholar +1 more source
New Insights Into Cancer Chronotherapies
Frontiers in Pharmacology, 2021 Circadian clocks participate in the coordination of various metabolic and biological activities to maintain homeostasis. Disturbances in the circadian rhythm and cancers are closely related.
Jingxuan Zhou +10 more
doaj +1 more source
Circadian Rhythms, Disease and Chronotherapy [PDF]
, 2021 Circadian clocks are biological timing mechanisms that generate 24-h rhythms of physiology and behavior, exemplified by cycles of sleep/wake, hormone release, and metabolism.
Field, Jeffrey +2 more
core +2 more sources