Results 41 to 50 of about 336,986 (421)
Disrupted circadian clocks and altered tissue mechanics in primary human breast tumours
Breast Cancer Research, 2018 Background Circadian rhythms maintain tissue homeostasis during the 24-h day-night cycle. Cell-autonomous circadian clocks play fundamental roles in cell division, DNA damage responses and metabolism.
Eleanor Broadberry +10 more
doaj +1 more source
Spectres of Clock Evolution: Past, Present, and Yet to Come
Frontiers in Physiology, 2022 Circadian clocks are phylogenetically widespread biological oscillators that allow organisms to entrain to environmental cycles and use their steady-state phase relationship to anticipate predictable daily phenomena – such as the light-dark transitions ...
Maria Luísa Jabbur +1 more
doaj +1 more source
A Molecular Link between the Circadian Clock, DNA Damage Responses, and Oncogene Activation [PDF]
, 2018 Circadian clocks enhance the efficiency and survival of living things by organizing their behavior and body functions. There has been a long history of research seeking a link between circadian clock and tumorigenesis.
Hirayama, Jun +2 more
core +1 more source
Circadian Rhythm and Chronobiology [PDF]
, 2018 All photosensitive organisms have a biological clock to cope with daily and seasonal circle of the earth. Biological clocks create circadian rhythms and regulate their processing according to cycle of the world.
Çakmur, Hülya
core +2 more sources
Circadian Clocks: Evolution in the Shadows [PDF]
Current Biology, 2009 As scientists, we strive for highly controlled conditions. The real world, however, is noisy. Complex networks are a coping mechanism for an erratic environment.
Marc F.P.M. Maas, Martha Merrow
openaire +4 more sources
Radical pairs can explain magnetic field and lithium effects on the circadian clock [PDF]
arXiv, 2021 Drosophila's circadian clock can be perturbed by magnetic fields, as well as by lithium administration. Cryptochromes are critical for the circadian clock. Further, the radical pairs in cryptochrome also can explain magnetoreception in animals. Based on a simple radical pair mechanism model of the animal magnetic compass, we show that both magnetic ...
arxiv
Kernel Architecture of the Genetic Circuitry of the Arabidopsis Circadian System [PDF]
PLoS Comput. Biol. 12, e1004748 (2016), 2016 A wide range of organisms features molecular machines, circadian clocks, which generate endogenous oscillations with ~24 h periodicity and thereby synchronize biological processes to diurnal environmental fluctuations. Recently, it has become clear that plants harbor more complex gene regulatory circuits within the core circadian clocks than other ...
arxiv +1 more source
Light-Dependent Regulation of Circadian Clocks in Vertebrates [PDF]
, 2019 Circadian clocks are intrinsic time-tracking systems that endow organisms with a survival advantage. The core of the circadian clock mechanism is a cell-autonomous and self-sustained oscillator called a cellular clock, which operates via a transcription-/
Hirayama, Jun +3 more
core +2 more sources
The Circadian Clock and Viral Infections [PDF]
Journal of Biological Rhythms, 2020 The circadian clock controls several aspects of mammalian physiology and orchestrates the daily oscillations of biological processes and behavior. Our circadian rhythms are driven by an endogenous central clock in the brain that synchronizes with clocks in peripheral tissues, thereby regulating our immune system and the severity of infections.
Helene Borrmann +2 more
openaire +3 more sources
A Level Set Kalman Filter Approach to Estimate the Circadian Phase and its Uncertainty from Wearable Data [PDF]
arXiv, 2022 The circadian clock is an internal timer that coordinates the daily rhythms of behavior and physiology, including sleep and hormone secretion. Accurately tracking the state of the circadian clock, or circadian phase, holds immense potential for precision medicine. Wearable devices present an opportunity to estimate the circadian phase in the real world,
arxiv