Results 61 to 70 of about 336,986 (421)
Circadian Clocks: Translation Lost [PDF]
One of the big questions in biological rhythms research is how a stable and precise circa-24 hour oscillation is generated on the molecular level. While increasing complexity seemed to be the key, a recent report suggests that circa-24 hour rhythms can be generated by just four molecules incubated in a test tube.
Martha Merrow, Till Roenneberg
openaire +2 more sources
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various preclinical epilepsy research disciplines.
Laura Bindila+11 more
wiley +1 more source
A broken circadian clock: The emerging neuro-immune link connecting depression to cancer
Circadian clocks orchestrate daily rhythms in many organisms and are essential for optimal health. Circadian rhythm disrupting events, such as jet-lag, shift-work, night-light exposure and clock gene alterations, give rise to pathologic conditions that ...
Keyu Su+11 more
doaj
The circadian nature of mitochondrial biology
Circadian clocks orchestrate the daily changes in physiology and behavior of light sensitive organisms. These clocks measure about 24 h and tick in a self-sustained and cell-autonomous manner.
Gal Manella, Gad Asher
doaj +1 more source
Regulation of Mammalian Physiology by Interconnected Circadian and Feeding Rhythms. [PDF]
Circadian clocks are endogenous timekeeping systems that adapt in an anticipatory fashion the physiology and behavior of most living organisms. In mammals, the master pacemaker resides in the suprachiasmatic nucleus and entrains peripheral clocks using a
Atger, F.+4 more
core +1 more source
Are There Circadian Clocks in Non-Photosynthetic Bacteria?
Circadian clocks in plants, animals, fungi, and in photosynthetic bacteria have been well-described. Observations of circadian rhythms in non-photosynthetic Eubacteria have been sporadic, and the molecular basis for these potential rhythms remains ...
Francesca Sartor+7 more
semanticscholar +1 more source
Cancer and the Circadian Clock
Abstract The circadian clock is a master regulator of mammalian physiology, regulating daily oscillations of crucial biological processes and behaviors. Notably, circadian disruption has recently been identified as an independent risk factor for cancer and classified as a carcinogen.
Ayesha A. Shafi, Karen E. Knudsen
openaire +4 more sources
Social information as an entrainment cue for the circadian clock [PDF]
Animals adapt to the daily changes in their environmental conditions by means of genetically encoded circadian clocks. These clocks, found throughout the tree of life, regulate diverse biological functions, and allow periodical changes in physiology and ...
Chiara Costa Petrillo+2 more
doaj +1 more source
Parametric modeling of mechanical effects on circadian oscillators [PDF]
Circadian rhythms are archetypical examples of nonlinear oscillations. While these oscillations are usually attributed to circuits of biochemical interactions among clock genes and proteins, recent experimental studies reveal that they are also affected by the cell's mechanical environment.
arxiv
Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters.
Many physiological processes exhibit circadian rhythms driven by cellular clocks composed of interlinked activating and repressing elements. To investigate temporal regulation in this molecular oscillator, we combined mouse genetic approaches and ...
Budak, H.+4 more
core +1 more source