Results 61 to 70 of about 336,986 (421)

Circadian Clocks: Translation Lost [PDF]

open access: yesCurrent Biology, 2005
One of the big questions in biological rhythms research is how a stable and precise circa-24 hour oscillation is generated on the molecular level. While increasing complexity seemed to be the key, a recent report suggests that circa-24 hour rhythms can be generated by just four molecules incubated in a test tube.
Martha Merrow, Till Roenneberg
openaire   +2 more sources

A companion to the preclinical common data elements for proteomics, lipidomics, and metabolomics data in rodent epilepsy models. A report of the TASK3‐WG4 omics working group of the ILAE/AES joint translational TASK force

open access: yesEpilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various preclinical epilepsy research disciplines.
Laura Bindila   +11 more
wiley   +1 more source

A broken circadian clock: The emerging neuro-immune link connecting depression to cancer

open access: yesBrain, Behavior, & Immunity - Health, 2022
Circadian clocks orchestrate daily rhythms in many organisms and are essential for optimal health. Circadian rhythm disrupting events, such as jet-lag, shift-work, night-light exposure and clock gene alterations, give rise to pathologic conditions that ...
Keyu Su   +11 more
doaj  

The circadian nature of mitochondrial biology

open access: yesFrontiers in Endocrinology, 2016
Circadian clocks orchestrate the daily changes in physiology and behavior of light sensitive organisms. These clocks measure about 24 h and tick in a self-sustained and cell-autonomous manner.
Gal Manella, Gad Asher
doaj   +1 more source

Regulation of Mammalian Physiology by Interconnected Circadian and Feeding Rhythms. [PDF]

open access: yes, 2017
Circadian clocks are endogenous timekeeping systems that adapt in an anticipatory fashion the physiology and behavior of most living organisms. In mammals, the master pacemaker resides in the suprachiasmatic nucleus and entrains peripheral clocks using a
Atger, F.   +4 more
core   +1 more source

Are There Circadian Clocks in Non-Photosynthetic Bacteria?

open access: yesBiology, 2019
Circadian clocks in plants, animals, fungi, and in photosynthetic bacteria have been well-described. Observations of circadian rhythms in non-photosynthetic Eubacteria have been sporadic, and the molecular basis for these potential rhythms remains ...
Francesca Sartor   +7 more
semanticscholar   +1 more source

Cancer and the Circadian Clock

open access: yesCancer Research, 2019
Abstract The circadian clock is a master regulator of mammalian physiology, regulating daily oscillations of crucial biological processes and behaviors. Notably, circadian disruption has recently been identified as an independent risk factor for cancer and classified as a carcinogen.
Ayesha A. Shafi, Karen E. Knudsen
openaire   +4 more sources

Social information as an entrainment cue for the circadian clock [PDF]

open access: yesGenetics and Molecular Biology
Animals adapt to the daily changes in their environmental conditions by means of genetically encoded circadian clocks. These clocks, found throughout the tree of life, regulate diverse biological functions, and allow periodical changes in physiology and ...
Chiara Costa Petrillo   +2 more
doaj   +1 more source

Parametric modeling of mechanical effects on circadian oscillators [PDF]

open access: yesarXiv, 2023
Circadian rhythms are archetypical examples of nonlinear oscillations. While these oscillations are usually attributed to circuits of biochemical interactions among clock genes and proteins, recent experimental studies reveal that they are also affected by the cell's mechanical environment.
arxiv  

Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters.

open access: yes, 2019
Many physiological processes exhibit circadian rhythms driven by cellular clocks composed of interlinked activating and repressing elements. To investigate temporal regulation in this molecular oscillator, we combined mouse genetic approaches and ...
Budak, H.   +4 more
core   +1 more source

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