Results 41 to 50 of about 64,689 (160)

Dysfunctional circadian-driven dynamics in gut microbiota and tumor microenvironment

Gut Microbes
Circadian rhythms govern physiological activities through the precise modulation of gene expression and biochemical functions. Dysfunction of circadian rhythms is associated with an increased risk of tumor formation, growth, and metastasis, as well as ...
Taoxing Peng, Yiqi Wan, Yuxuan Sun, Yuexiang Ren, Fuli Shi, Yangfeng Lv, Xiangqiong Wen, Qiongfeng Chen, Xianhe Yang, Shan Xu, Jianming Li   +10 more
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Study on the Correlation Between the Genetics of Circadian Rhythms and Neurodegenerative Diseases [PDF]

BIO Web of Conferences
In the context of global population aging, the increasing incidence of neurodegenerative diseases presents a serious challenge to healthcare systems worldwide.
Yin Yueci
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Importance of Circadian Rhythms in the Ocular Surface

Biomolecules
Circadian rhythms are a ubiquitous feature throughout the organism. Accumulating evidence suggests that the dysfunction of circadian rhythms due to genetic mutations or environmental factors contributes to the genesis and progress of multiple diseases ...
Xiaozhao Zhang, Ying Jie
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The calcineurin-NFAT pathway controls activity-dependent circadian gene expression in slow skeletal muscle

Molecular Metabolism, 2015
Objective: Physical activity and circadian rhythms are well-established determinants of human health and disease, but the relationship between muscle activity and the circadian regulation of muscle genes is a relatively new area of research.
Kenneth A. Dyar, Stefano Ciciliot, Guidantonio Malagoli Tagliazucchi, Giorgia Pallafacchina, Jana Tothova, Carla Argentini, Lisa Agatea, Reimar Abraham, Miika Ahdesmäki, Mattia Forcato, Silvio Bicciato, Stefano Schiaffino, Bert Blaauw   +12 more
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Molecular insights of Circadian Rhythm in Chilopoda [PDF]

Journal of Stress Physiology & Biochemistry
The control of the sleep-wake cycle as well as several physiological and behavioral processes in living things depends on circadian rhythms. Circadian rhythms are regulated by internal biological clocks that coordinate with environmental stimuli like ...
Malathi R., Janice Marianne John
doaj  

Unveiling the novel role of circadian rhythms in sepsis and septic shock: unexplored implications for chronotherapy

Frontiers in Endocrinology
Circadian rhythms are critical to coordinating body processes to external environmental cues, such as light and feeding, to ensure efficiency and maintain optimal health. These rhythms are controlled by ‘clock’ transcription factors, such as Clock, Bmal1,
Stewart D. Ramsay, Stewart D. Ramsay, Stewart D. Ramsay, Marni A. Nenke, Marni A. Nenke, Emily J. Meyer, Emily J. Meyer, David J. Torpy, David J. Torpy, Richard L. Young, Richard L. Young, Richard L. Young, Richard L. Young   +12 more
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Circadian rhythms of macrophages are altered by the acidic tumor microenvironment

EMBO Reports
Tumor-associated macrophages (TAMs) are prime therapeutic targets due to their pro-tumorigenic functions, but varying efficacy of macrophage-targeting therapies highlights our incomplete understanding of how macrophages are regulated within the tumor ...
Amelia M Knudsen-Clark, Daniel Mwangi, Juliana Cazarin, Kristina Morris, Cameron Baker, Lauren M Hablitz, Matthew N McCall, Minsoo Kim, Brian J Altman   +8 more
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Potential bidirectional communication between the liver and the central circadian clock in MASLD

npj Metabolic Health and Disease
Most aspects of physiology and behaviour fluctuate every 24 h in mammals. These circadian rhythms are orchestrated by an autonomous central clock located in the suprachiasmatic nuclei that coordinates the timing of cellular clocks in tissues throughout ...
Frédéric Gachon, Elisabetta Bugianesi, Gabriele Castelnuovo, Henrik Oster, Julie S. Pendergast, Sara Montagnese   +5 more
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Sympathetic NPY controls glucose homeostasis, cold tolerance, and cardiovascular functions in mice

Cell Reports
Summary: Neuropeptide Y (NPY) is best known for its effects in the brain as an orexigenic and anxiolytic agent and in reducing energy expenditure. NPY is also co-expressed with norepinephrine (NE) in sympathetic neurons.
Raniki Kumari, Raluca Pascalau, Hui Wang, Sheetal Bajpayi, Maria Yurgel, Kwaku Quansah, Samer Hattar, Emmanouil Tampakakis, Rejji Kuruvilla   +8 more
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The blues and rhythm

Neuroscience Research
Most organisms, including humans, show daily rhythms in many aspects of physiology and behavior, and abnormalities in the rhythms are potential risk factors for various diseases. Mood disorders such as depression are no exception.
Kiyomichi Imamura, Ayaka Bota, Toshihiko Shirafuji, Toru Takumi   +3 more
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