Results 61 to 70 of about 86,709 (313)

Mechanism for 12 Hr Rhythm Generation by the Circadian Clock

Cell Reports, 2013
In addition to the well-known circadian rhythms in animal behavior, cell biology, and gene expression, there are also 12 hr rhythms. The mechanism giving rise to these 12 hr rhythms is not clear.
Pål O. Westermark, Hanspeter Herzel
doaj   +1 more source

Human Circadian Phase Estimation from Signals Collected in Ambulatory Conditions Using an Autoregressive Model [PDF]

, 2013
Phase estimation of the human circadian rhythm is a topic that has been explored using various modeling approaches. The current models range from physiological to mathematical, all attempting to estimate the circadian phase from different physiological ...
Gil, Enrique A, Møst, Els I S, Beersma, Domien G M, Beersma, Domien G. M., Møst, Els I.S., Aubert, Xavier L, Gil, Enrique A.,, Aubert, Xavier L.,, Aubert, Xavier L., Beersma, Domien G.M.,, Most, Els I. S., Gil, Enrique A., Møst, Els I.S.,   +12 more
core   +1 more source

Hijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control

Advanced Science, EarlyView.
Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang, Yufeng Xu, Yanfei Hu, Lijun Cao, Ru Jiang, Changtian Chen, Rick Masonbrink, Thomas Maier, Yuchen Tu, Yabo Shi, Enhui Liu, Lingan Kong, Chan Guo, Wei Zhao, Peng Shi, Wenzhen Du, Andrew Severin, Thomas Baum, Deliang Peng, Huan Peng, Mian Zhou, Wei Wang   +21 more
wiley   +1 more source

Pathophysiological Models of Hypersomnolence Associated With Depression

Biological Psychiatry Global Open Science
Up to 25% of patients with depression experience hypersomnolence (e.g., excessive daytime sleepiness, hypersomnia, and/or sleep inertia), which is associated with treatment resistance, overall poorer outcomes, and safety concerns while driving ...
Christophe Moderie, Diane B. Boivin
doaj   +1 more source

Adult Circadian behavior in Drosophila requires developmental expression of cycle, but not period

, 2011
Circadian clocks have evolved as internal time keeping mechanisms that allow anticipation of daily environmental changes and organization of a daily program of physiological and behavioral rhythms.
Bonilla Gloribel, Goda Tadahiro, Tadahiro Goda, Neethi Varadaraja Rao, Herman Wijnen, Wijnen Herman, Currie, Jake, Kim Min-Ho, Karolina Mirowska, Rao Neethi Varadaraja, Gloribel Bonilla, Goda, Tadahiro, Wijnen, Herman, Rao, Neethi Varadaraja, Mirowska, Karolina, Kim, Min-Ho, Bonilla, Gloribel, Bonilla Herman, Min-Ho Kim, Currie Jake, Mirowska Karolina, Jake Currie   +21 more
core   +1 more source

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

The neurobiology of circadian rhythms [PDF]

Current Opinion in Pulmonary Medicine, 2009
There is growing awareness of the importance of circadian rhythmicity in various research fields. Exciting developments are ongoing in the field of circadian neurobiology linked to sleep, food intake, and memory. With the current knowledge of critical 'clock genes' (genes found to be involved in the generation of circadian rhythms) and novel techniques
Eddy A, Van der Zee, Gretha J, Boersma, Roelof A, Hut   +2 more
openaire   +2 more sources

FLOWERING LOCUS C -dependent and -independent regulation of the circadian clock by the autonomous and vernalization pathways [PDF]

, 2006
Background The circadian system drives pervasive biological rhythms in plants. Circadian clocks integrate endogenous timing information with environmental signals, in order to match rhythmic outputs to the local day/night cycle.
Salathia Neeraj, Andrew J Millar, Amasino, R., Michaels, Scott D, Lynn, J., Millar Andrew J, Millar, A., Lynn, James R, Davis, S. J., Lynn, J. R., Michaels, Scott D., Amasino Richard M, Davis, Seth J., Salathia, N., Millar, A. J., Lynn James R, Lynn, James R., Neeraj Salathia, Davis, Seth J, Michaels Scott D, Richard M Amasino, Amasino, Richard M., Davis, S., Michaels, S. D., Amasino, Richard M, Amasino, R. M., Michaels, S., Seth J Davis, Davis Seth J, Millar, Andrew J; id_orcid, Millar, A. J. (Andrew J.), Scott D Michaels, Salathia, Neeraj, James R Lynn   +33 more
core   +1 more source

Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction

Advanced Science, EarlyView.
During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao, Shenghui Huo, Yue Xing, Shuxin Zhang, Guilin Li, Yihui Liu, Chongyang Jin, Fuguang Li, Xiaoyang Ge   +8 more
wiley   +1 more source