Results 81 to 90 of about 86,709 (313)

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Circadian disruption and sleep disorders in neurodegeneration

Translational Neurodegeneration, 2023
Disruptions of circadian rhythms and sleep cycles are common among neurodegenerative diseases and can occur at multiple levels. Accumulating evidence reveals a bidirectional relationship between disruptions of circadian rhythms and sleep cycles and ...
Yun Shen, Qian-kun Lv, Wei-ye Xie, Si-yi Gong, Sheng Zhuang, Jun-yi Liu, Cheng-jie Mao, Chun-feng Liu   +7 more
doaj   +1 more source

Understanding Biological Mechanisms: Using Illustrations from Circadian Rhythm Research [PDF]

, 2012
In many fields of biology, researchers explain a phenomenon by characterizing the responsible mechanism. This requires identifying the candidate mechanism, decomposing it into its parts and operations, recomposing it so as to understand how it is ...
Bechtel, William
core  

A High‐Throughput Live Imaging Platform to Investigate Circuit‐Dependent Regulation of Circadian Rhythms in Brain Tissue

Advanced Science, EarlyView.
Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari, Natalie Ness, Julieta Acosta, Marco Brancaccio   +3 more
wiley   +1 more source

Hierarchically coupled ultradian oscillators generating robust circadian rhythms

, 1997
Ensembles of mutually coupled ultradian cellular oscillators have been proposed by a number of authors to explain the generation of circadian rhythms in mammals.
Maini, P. K., Barrio, R. A., Zhang, L., Zhang, L, Maini, Philip, Maini, PK, Barrio, RA   +6 more
core   +1 more source

An Energy Autonomous Microneedle Array‐Based Sensing System for Continuous Biomarker Monitoring

Advanced Science, EarlyView.
This work presents an innovative self‐powered wearable biosensor system for real‐time monitoring of multiple biomarkers in interstitial fluid. The device integrates stainless steel‐based minimally invasive microneedles with ion‐selective membranes, enabling simultaneous Na+, K+, Ca2+, pH, and glucose detection.
Arnab Pal, Kai‐Po Fan, Sheng‐Chun Hung, Jaba Roy Chowdhury, Jun‐Hsun Chung, Meenakshi Ray, Hsiang‐Yun Hsu, Fu‐Cheng Kao, Kuei‐Lin Liu, Zong‐Hong Lin   +9 more
wiley   +1 more source

Wearable‐Derived Diurnal Alignment Between Physical Activity and Device Temperature Predicts Future Disease and Mortality Risk

Advanced Science, EarlyView.
Wearable‐derived diurnal alignment between physical activity and device temperature, decomposed into 24 h coupling strength (M24), phase deviation (D24), and 12 h harmonic magnitude (M12), is examined in approximately 90,000 UK Biobank participants.
Han Chen, Jiahe Wei, Jonathan Cedernaes, Christian Benedict, Athanasios Tsanas, Zhi Cao, Xiao Tan   +6 more
wiley   +1 more source

Higher central circadian temperature amplitude is associated with greater metabolite rhythmicity in humans

Scientific Reports
Robust circadian rhythms are essential for optimal health. The central circadian clock controls temperature rhythms, which are known to organize the timing of peripheral circadian rhythms in rodents.
Daniel P. Windred, Clare Anderson, Katherine J. Jeppe, Suzanne Ftouni, Leilah K. Grant, Brunda Nijagal, Shantha M. W. Rajaratnam, Malcolm McConville, Dedreia Tull, Steven W. Lockley, Sean W. Cain, Andrew J. K. Phillips   +11 more
doaj   +1 more source

The role of temperature on the development of circadian rhythms in honey bee workers [PDF]

PeerJ
Circadian rhythms in honey bees are involved in various processes that impact colony survival. For example, young nurses take care of the brood constantly throughout the day and lack circadian rhythms.
Manuel A. Giannoni-Guzmán, Eddie Perez Claudio, Janpierre Aleman-Rios, Gabriel Diaz Hernandez, Melina Perez Torres, Alexander Melendez Moreno, Darimar Loubriel, Darrell Moore, Tugrul Giray, Jose L. Agosto-Rivera   +9 more
doaj   +2 more sources

Forward genetic analysis of the circadian clock separates the multiple functions of ZEITLUPE [PDF]

, 2006
The circadian system of Arabidopsis ( Arabidopsis thaliana) includes feedback loops of gene regulation that generate 24-h oscillations. Components of these loops remain to be identified; none of the known components is completely understood, including ...
Gyula, Peter, Hanano, S., Southern, M., Millar, A., Davis, S. J., Eriksson, Maria,, Kevei, Eva, Bastow, R. M., Davis, Seth J., Millar, A. J., Somers, D., Bastow, Ruth M, Somers, David E, Bastow, R., Viczian, A., Kozma-Bognar, L., Eriksson, Maria E., Viczian, Andras, Nagy, Ferenc, Davis, Seth J, Hanano, Shigeru, Hibberd, Victoria, Kevei, E., Davis, S., Kozma-Bognar, Laszlo, Millar, Andrew J, Bastow, Ruth, Hibberd, V., Toth, R., Kim, Woe-Yeon, Southern, Megan M, Eriksson, M. E., Hall, Anthony, Somers, D. E., Eriksson, Maria E, Kim, W., Somers, David E., Eriksson, M., Southern, Megan M., Gyula, P., Southern, M. M., Toth, Reka, Millar, Andrew J; id_orcid, Hall, A., Kim, W. Y., Nagy, F., Feher, Balazs, Feher, B.   +47 more
core   +1 more source