Results 51 to 60 of about 213,878 (305)

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

Global parameter search reveals design principles of the mammalian circadian clock [PDF]

, 2008
Background: Virtually all living organisms have evolved a circadian (~24 hour) clock that controls physiological and behavioural processes with exquisite precision throughout the day/night cycle.
Locke, James C. W., Kramer, Achim, Herzel, Hanspeter, Westermark, Pål O.   +3 more
core   +1 more source

Falls risk, circadian rhythms and melatonin : current perspectives [PDF]

, 2020
: Aging is associated with weakening of the circadian system. The circadian amplitude of most physiological variables is reduced, while the circadian phase becomes more labile and tends to occur earlier with advancing age.
Goswami, Nandu, Abulafia, Carolina Andrea, Cardinali, Daniel, Moser, Maximilian, Vigo, Daniel Eduardo, Cornelissen, Germaine, Cardinali, Daniel Pedro, Abulafia, Carolina, Vigo, Daniel   +8 more
core   +1 more source

Disentangling the Genetic Relationship Between Sleep and Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective A bidirectional relationship between sleep and epilepsy is well recognised, yet the biological mechanisms linking them remain poorly understood. Both have a genetic basis, with genome‐wide association studies (GWAS) capturing polygenic contributions.
Khang N. Le, Victoria E. Jackson, Rachel E. Stirling, Zachary F. Gerring, Remi Stevelink, Samuel F. Berkovic, Ingrid E. Scheffer, Philippa J. Karoly, Melanie Bahlo, Karen L. Oliver   +9 more
wiley   +1 more source

Circadian rhythms in parasites

PLOS Pathogens, 2017
Copyright: © 2017 Rijo-Ferreira et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Filipa Rijo-Ferreira, Joseph S. Takahashi, Luisa M. Figueiredo   +2 more
openaire   +5 more sources

ELF4 is required for oscillatory properties of the circadian clock [PDF]

, 2007
Circadian clocks are required to coordinate metabolism and physiology with daily changes in the environment. Such clocks have several distinctive features, including a free-running rhythm of approximately 24 h and the ability to entrain to both light or ...
Nagy, Ferenc, Davis, Seth J, Gyula, Péter, Amasino, R., Davis, S., Millar, A., Hall, Anthony, Amasino, Richard M, McWatters, Harriet G, Doyle, M., Doyle, Mark R, Kolmos, E., Gyula, P., Millar, Andrew J; id_orcid, Hall, A., Nagy, F., McWatters, H., Kolmos, Elsebeth   +17 more
core   +1 more source

Life‐Like Ferrous Oxide Microspheres from Kombucha

Advanced Materials Interfaces, EarlyView.
Kombucha bacterial cellulose, sodium alginate, and ferrous nitrate self‐assemble into membrane‐enclosed iron oxide microspheres. These microspheres bud daughter vesicles, sustain 24‐h electrochemical oscillations, and filter theta‐band signals.
Panagiotis Mougkogiannis, Anna Nikolaidou, Andrew Adamatzky   +2 more
wiley   +1 more source

A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans

Advanced Science, EarlyView.
This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao, Yu‐Xin Zhang, Xiao‐Xing Liu, Zi‐Hang Li, Tang‐Sheng Lu, Jia‐Hui Deng, Wen Zhang, Peng Li, Xiao Lin, Shu‐Fei Feng, Ting‐Ting Li, Shi‐Qiu Meng, Xiang‐Dong Tang, Tian‐Ye Jia, Trevor W. Robbins, Jie Shi, Ying Han, Yan‐Xue Xue, Lin Lu, Kai Yuan   +19 more
wiley   +1 more source

Home-Court Advantage and the Associations of Travel and Jet Lag with Team Performance in the Women’s National Basketball Association (WNBA)

Sports Medicine - Open
Background Travel-related fatigue and circadian disruption (i.e., jet lag) are well-established factors limiting performance in elite men’s sport and are recognized contributors to home advantage.
Josh Leota, Dean J. Miller, Mark É. Czeisler, Jesse Cook, Luis Mascaro, Tim D. Smithies, Ayden Nelthropp, Elise R. Facer-Childs   +7 more
doaj   +1 more source

Circadian Rhythms and Mood Disorders: Are The Phenomena and Mechanisms Causally Related?

Frontiers in Psychiatry, 2015
This paper reviews some of the compelling evidence of disrupted circadian rhythms in individuals with mood disorders (major depressive disorder, seasonal affective disorder, and bipolar disorder) and that treatments such as bright light, designed to ...
William eBechtel
doaj   +1 more source