Results 51 to 60 of about 86,709 (313)

Genetics of Circadian Rhythms

Neurologic Clinics, 2019
In mammals, genetic influences of circadian rhythms occur at many levels. A set of core "clock genes" have been identified that form a feedback loop of gene transcription and translation. The core genetic clockwork generates circadian rhythms in cells throughout the body.
Martha Hotz, Vitaterna, Kazuhiro, Shimomura, Peng, Jiang   +2 more
openaire   +3 more sources

Circadian rhythms in RA [PDF]

Annals of the Rheumatic Diseases, 2003
Possible roles of cortisol and melatonin It is well known that some clinical signs and symptoms of rheumatoid arthritis (RA) vary within a day and between days, and the morning stiffness seen in patients with RA has become one of the diagnostic criteria of the disease (fig 1).1 Figure 1 Clinical signs and symptoms of articular inflammation in ...
CUTOLO, MAURIZIO, SERIOLO, BRUNO, Craviotto C, PIZZORNI, CARMEN, SULLI, ALBERTO   +4 more
openaire   +3 more sources

Effect of deuterium on the circadian period and metabolism in wild-type and tau mutant Syrian hamsters [PDF]

, 2000
Homozygous tau mutant Syrian hamsters (tau-/-) have a free-running circadian period (τ) around 20 h and a proportionally higher metabolic rate compared with wild-type hamsters (tau+/+) with a period of circa 24 h.
Malgorzata Oklejewicz, Daan, S, Hut, Roelof A.,, Hut, RA, Roelof A Hut, Serge Daan, Daan, Serge,, Oklejewicz, M, Oklejewicz, Malgorzata,   +8 more
core   +1 more source

Associations of Sleep and Shift Work With Osteoarthritis Risk

Arthritis Care &Research, EarlyView.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik, Abigail Bridgeman, Erik D. Herzog, Vy Pham, Bradley A. Evanoff, Farshid Guilak   +5 more
wiley   +1 more source

Circadian Rhythms and Mood Disorders: Are The Phenomena and Mechanisms Causally Related?

Frontiers in Psychiatry, 2015
This paper reviews some of the compelling evidence of disrupted circadian rhythms in individuals with mood disorders (major depressive disorder, seasonal affective disorder, and bipolar disorder) and that treatments such as bright light, designed to ...
William eBechtel
doaj   +1 more source

Polymorphisms in the circadian expressed genes PER3 and ARNTL2 are associated with diurnal preference and GNβ3 with sleep measures [PDF]

, 2014
Sleep and circadian rhythms are intrinsically linked, with several sleep traits, including sleep timing and duration, influenced by both sleep homeostasis and the circadian phase.
Lester, Kathryn, Lester, KJ, Archer, Simon, Archer, SN, Gregory, Alice M, Lester, Kathryn J., Barclay, Nicola L., Gregory, Alice, Nolan, Patrick M., Nolan, PM, Nolan, Patrick, Parsons, Michael J., Eley, Thalia C, Archer, Simon N., Barclay, Nicola, Gregory, AM, Patrick M Nolan (11641339), Barclay, Nicola L, Eley, Thalia C., Nolan, Patrick M, Archer, Simon N, Parsons, Michael J, Kathryn Lester (4462210), Nicola L Barclay (16221641), Parsons, Michael, Thalia C Eley (13615696), Parsons, MJ, Eley, Thalia, Simon N Archer (16221644), Alice M Gregory (11992776), Lester, Kathryn J, Michael J Parsons (16221638), Gregory, Alice M., Eley, TC, Barclay, NL   +34 more
core   +1 more source

Nocturnal Intraocular Pressure Monitoring With a Soft Contact Lens Sensor for Glaucoma Management

Advanced Materials, EarlyView.
A soft contact lens sensor enables continuous, noninvasive monitoring of nocturnal intraocular pressure (IOP) under closed‐eye sleep conditions. By integrating a highly compliant inductive–capacitive circuit onto a commercial lens, the device achieves record sensitivity and stable performance.
Yumin Dai, Tristan Michael Long, Oluwabunmi T. Oladele, Youngoh Lee, Feiyang Li, Ziheng Wang, Yeonji Oh, Junsang Lee, Taewoong Park, Tianhao Yu, Seokkyoon Hong, Kyeonghee Lim, Jinheon Jeong, Dawn Meyer Schneider, Hyerim Ra, Bryan W. Boudouris, Gillian C. Shaw, Shin Ae Park, Pete S. Kollbaum, Chi Hwan Lee   +19 more
wiley   +1 more source

Circadian rhythms in parasites

PLOS Pathogens, 2017
Copyright: © 2017 Rijo-Ferreira et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Filipa Rijo-Ferreira, Joseph S. Takahashi, Luisa M. Figueiredo   +2 more
openaire   +5 more sources

Non-alcoholic Fatty pancreas disease pathogenesis: a role for developmental programming and altered circadian rhythms. [PDF]

, 2014
Emerging evidence suggests that maternal obesity (MO) predisposes offspring to obesity and the recently described non-alcoholic fatty pancreas disease (NAFPD) but involved mechanisms remain unclear.
Mouralidarane Angelina, Chiara Saracino, Lucilla Poston (200809), Francesca Rappa, Ruma Saraswati, Fusai, Giuseppe, Paul D. Taylor (200813), Pazienza Valerio, Junpei Soeda, Carter, Rebeca, Jude A Oben, Angelina Mouralidarane (540950), Saraswati Ruma, Paul D Taylor, Mouralidarane, Angelina, Oben, JA, Saraswati, R, Fusai Giuseppe, Marco Novelli, Carter, R, Poston Lucilla, Marco Novelli (540954), Giuseppe Fusai (540955), Shuvra Ray (540951), Soeda, Junpei, Soeda, J, Pombo, J, Mouralidarane, A, Rappa, F, Ruma Saraswati (540953), Pazienza, Valerio, Novelli, Marco, Taylor Paul D., Joaquim Pombo (540952), Carter Rebeca, Saracino, C, Manlio Vinciguerra (287299), Saraswati, Ruma, Novelli, M, Oben, Jude A, Angelina Mouralidarane, Pombo, Joaquim, Fusai, G, RAPPA, Francesca, Saracino, Chiara, Novelli Marco, Rappa Francesca, Lucilla Poston, Francesca Rappa (55683), Manlio Vinciguerra, Rebeca Carter, Saracino Chiara, Poston, Lucilla; id_orcid, Pazienza, V, Vinciguerra, M, Joaquim Pombo, Rebeca Carter (540949), Ray Shuvra, Vinciguerra, Manlio, Vinciguerra, M. Oben J.A., Junpei Soeda (453348), Valerio Pazienza, Poston, L, Vinciguerra Manlio, Ray, S, Jude A. Oben (453352), Taylor, PD, Soeda Junpei, Giuseppe Fusai, Oben Jude A., Pombo Joaquim, Valerio Pazienza (174196), Taylor, Paul D; id_orcid, Chiara Saracino (540956), Ray, Shuvra, Shuvra Ray   +75 more
core   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source