Results 201 to 210 of about 45,661 (289)
The role of circRNAs in resistance to doxorubicin
Cell Communication and SignalingDoxorubicin is an anthracyline recognized as an antitumor antibiotic agent. It is widely used in the chemotherapeutic regimens in different types of cancers. Resistance to doxorubicin is a major clinical obstacle and main cause of failure in cancer chemotherapy.
Mahla Sanati, Soudeh Ghafouri-Fard
openaire +3 more sources
Identification of circRNA biomarkers in osteosarcoma: An updated systematic review and meta-analysis [PDF]
Circular RNAs (circRNAs) play a crucial role in cancer development and progression. This study aimed to identify potential circRNA biomarkers for osteosarcoma. Articles published from January 2010 to September 2023 were searched across eight databases to
Balmer, Lois +6 more
core +2 more sources
Journal of Inflammation ResearchHong Chen,* Xie Wang,* Nian Peng, Yue Pu, Hao Ye, Yu Gui, Rui Zhang, Juan Zhang Department of Neurology, The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, 230031, People’s Republic of China*These ...
Chen H +7 more
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MedComm, Volume 6, Issue 10, October 2025.In TME, undetectable DCCs (panel A) join with a low tumor burden along with low immune suppression, that favor successful immune manipulation through immune suppression inhibiting immune‐therapy. This moves the immune balance toward the immune response and likely makes more stable the dormant state of DCCs in the unstable metastatic niche and/or allows
Andrea Nicolini +3 more
wiley +1 more source
EXPRESSION OF CONCERN: Discovery of a Novel Viroid‐Like Circular RNA in Colorectal Cancer
Cancer Communications, EarlyView.
wiley +1 more source
MedComm, Volume 6, Issue 10, October 2025.Hypertrophic scars and keloids highlight distinct epidemiology, multifactorial triggers (genetic, mechanical, medical), and dysregulated signaling hubs (TGF‐β, Integrin‐FAK, Wnt/β‐catenin). Emerging interventions targeting fibroblast plasticity, inflammation, and biomechanics via gene editing, immune modulation, and biomaterials are increasingly ...
Xiaowan Fang +7 more
wiley +1 more source
Heart Regeneration and Repair: Molecular Mechanism and Therapeutic Targets
MedComm, Volume 6, Issue 10, October 2025.Regarding the general picture of heart regeneration therapy, it encompasses exogenous cell therapy, endogenous medications, metabolism, interventions in gene pathways, as well as the therapeutic strategies in the burgeoning interdisciplinary field of medicine and engineering in recent years.
Mingchuan Liu +9 more
wiley +1 more source
CircCDYL Association With hnRNPL Modulates CDYL Isoform Switching in Breast Cancer Cells
Cancer Science, Volume 116, Issue 10, Page 2750-2762, October 2025.We investigated the synergic role of the circRNA circCDYL and the splicing factor hnRNPL in modulating alternative splicing and isoform switch in breast cancer cells, with a focus on circCDYL and hnRNPL‐mediated isoform switch events involving the CDYL gene.
Serena Bernardi +11 more
wiley +1 more source
Extracellular vesicles in multiple myeloma: pathogenesis and therapeutic application
The FEBS Journal, Volume 292, Issue 19, Page 4979-4991, October 2025.Multiple myeloma is characterised by the clonal proliferation of plasma cells in the bone marrow. Extracellular vesicles (EVs) are a key component of cell‐to‐cell communication within the bone marrow microenvironment, promoting tumour growth, bone remodelling, immune modulation, angiogenesis and therapeutic resistance.
Chloe Wylie +3 more
wiley +1 more source
Journal of Inflammation ResearchCai-Dong Liu,1,2,* Qiang Peng,3,* Shi-Yao Wang,3,* Yang Deng,2 Zhong-Yuan Li,3 Zhao-Han Xu,3 Liang Wu,3 Ying-Dong Zhang,2,3 Rui Duan3 1Department of Laboratory Medicine, Nanjing First Hospital, China Pharmaceutical University, Nanjing ...
Liu CD +8 more
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