Results 181 to 190 of about 30,287 (286)

Major Depressive Disorder Signatures: A Review of Artificial Intelligence (AI)‐Powered Insights Into Gut Dysbiosis

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Major Depressive Disorder (MDD) is a highly common neuropsychiatric disorder globally. A variety of factors contribute to the neuropathology of MDD. Microbiome research in neuropsychiatric disorders such as MDD has recently attracted attention. Indeed, the gut‐brain axis could influence the course of MDD through metabolites
Nazanin Zahra Keshvari   +6 more
wiley   +1 more source

mRNA Therapeutics Beyond Infectious Diseases: Expanding Therapeutic Applications and Future Perspectives

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.
Messenger RNA therapeutics are rapidly expanding beyond infectious diseases into oncology, autoimmune disorders, protein replacement therapy, cardiovascular and neurological diseases, and regenerative medicine. Advances in RNA engineering and targeted delivery are driving the development of safe, programmable, and precision therapeutics for diverse ...
Gedion Mengistu Dejen
wiley   +1 more source

Artificial intelligence driven diet‐intestinal microbiota‐host health integration: A four‐dimensional paradigm for advancing host wellness research

open access: yesiMetaOmics, Volume 3, Issue 3, September 2026.
This graphical abstract presents a novel Diet‐Artificial Intelligence (AI)‐intestinal Microbiota–Host Health paradigm integrating microbiota‐centric pathways and an AI‐driven multi‐omics workflow. Diet shapes gut bacteria that regulate intestinal mucosal integrity, immune signaling, and gut–brain neurotransmitters to influence host health.
Tianle He   +16 more
wiley   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

open access: yesiNew Medicine, Volume 2, Issue 3, September 2026.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little   +12 more
wiley   +1 more source

Engineering Extracellular Vesicles: Strategies for Functional Modification and Clinical Translation

open access: yesiNew Medicine, Volume 2, Issue 3, September 2026.
The engineering modification strategies of extracellular vesicles (EVs). This figure presents the four core technical systems for the engineering modification of EVs, including direct modification strategies (physical and chemical methods), biological engineering methods, and hybrid and bionic strategies.
Zhouming Cheng   +3 more
wiley   +1 more source

Biomimetic mineralization‐inspired formulation‐adjuvant integrated circRNA nanovaccine against COVID‐19

open access: yesInterdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Inspired by the role of Mg2+ in stabilizing RNA secondary structures, we developed a one‐pot biomimetic mineralization method for synthesizing a circular RNA‐based nanovaccine (circRNA@FAiNVac) that integrates formulation and adjuvant functions. This nanovaccine exhibits potent immunostimulatory activation enabling multimodal immune responses and ...
Liangru Lin   +10 more
wiley   +1 more source

Advances in the Study of Non-Coding RNA in the Signaling Pathway of Pulmonary Fibrosis

open access: yesInternational Journal of General Medicine
Dengyun Pan, Xin Di, Bingdi Yan, Xiaomin Su Department of Respiratory Medicine, The Second Hospital of Jilin University, Changchun, People’s Republic of ChinaCorrespondence: Bingdi Yan; Xiaomin Su, Department of Respiratory Medicine, The Second Hospital ...
Pan D, Di X, Yan B, Su X
doaj  

CircFut8 Suppresses Bladder Cancer by Modulating SRSF9‐Dependent Pre‐mRNA Splicing

open access: yesThe Journal of Gene Medicine, Volume 28, Issue 9, September 2026.
This schematic illustrates the mechanism by which circFut8 suppresses bladder cancer progression. Under high circFut8 levels, circFut8 competitively binds the splicing factor SRSF9, reducing SRSF9's association with FUT8 pre‐mRNA. This promotes exon 3 skipping, leading to increased production of the FUT8‐4 splice variant, which correlates with reduced ...
Weifeng Yang   +3 more
wiley   +1 more source

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