Results 201 to 210 of about 30,287 (286)
Enhancing Lipid Nanoparticle-Mediated Circular RNA and mRNA Expression in the Placenta through Inhibition of IFNAR-JAK-STAT Signaling. [PDF]
Safford HC +14 more
europepmc +1 more source
Abstract Genome–phenome association (GPA) prediction can broaden the understanding of biological mechanisms underlying complex phenotypic traits (e.g., diseases and agronomic traits). Traditional deep matrix factorization (DMF)‐based GPA methods can integrate multiple data types and uncover nonlinear associations but often rely on low‐dimensional ...
Ran Duan +4 more
wiley +1 more source
Target site selection and P1 engineering enable highly efficient circular RNA production via end-to-end self-targeting and splicing. [PDF]
Lee KH, Kim S, Cha J, Lee SW.
europepmc +1 more source
Cancer nanovaccines have emerged as promising alternatives to conventional cancer vaccines, which have shown limited clinical efficacy. In particular, cell membrane nanoparticle‐based nanovaccines can offer high biocompatibility and immunogenicity while preserving tumor antigens, including antigen repertoires.
Munsik Kim, Ilkoo Noh
wiley +1 more source
Split intron-exon system for circular RNA synthesis. [PDF]
Wang L +11 more
europepmc +1 more source
PAE creates a unique inflammatory signature in the mature adult brain with region‐specific changes in genes implicated in glial‐immune function. We report at least 60 differentially expressed genes in different brain regions due to PAE, many of which are associated with neuroimmune function.
Alissa N. Jones +6 more
wiley +1 more source
A Tailored Workflow for Circular RNA Enrichment and Analysis from Human Whole Blood. [PDF]
Cieri F +6 more
europepmc +1 more source
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
Franziska Roth‐Walter +20 more
wiley +1 more source
Whole-transcriptome sequencing analysis to identify key non-coding RNAs in the pathogenesis of pulmonary tuberculosis. [PDF]
Liu MB +5 more
europepmc +1 more source
ABSTRACT Background Sperm acquire fertility ability during epididymal maturation mainly in the epididymal caput and corpus, and once matured, are stored in the epididymal cauda. During storage, interactions with cauda epididymosomes (epEVs) may influence sperm fertility potential; however, the role of such interactions on sperm fertility remains ...
Maíra Bianchi Rodrigues Alves +7 more
wiley +1 more source

