Results 171 to 180 of about 28,713 (267)
Journal of Inflammation ResearchHong Chen,* Xie Wang,* Nian Peng, Yue Pu, Hao Ye, Yu Gui, Rui Zhang, Juan Zhang Department of Neurology, The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, 230031, People’s Republic of China*These ...
Chen H +7 more
doaj
The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 6, June 2026.ABSTRACT Triple‐negative breast cancer (TNBC) is characterized as an aggressive malignancy with limited therapeutic options. The circular RNA circ_0006174 has been implicated in oncogenic processes across various cancers; however, its specific role in the pathogenesis of TNBC remains unclear.
Yong‐Zhe Tang +4 more
wiley +1 more source
CircRNAs in the heart: bricks in Brunelleschi’s Dome [PDF]
Cardiovascular Research, 2020 Paula A da Costa Martins +1 more
openaire +3 more sources
NCPCDA: network consistency projection for circRNA–disease association prediction
, 2019 A growing body of evidence indicates that circular RNAs (circRNAs) play a pivotal role in various biological processes and have a close association with the initiation and progression of diseases. Moreover, circRNAs are considered as promising biomarkers
Yue, Yingjie +11 more
core +1 more source
Epigenetic Regulation in Cardiovascular Diseases: Mechanisms and Therapeutic Targets
MedComm, Volume 7, Issue 6, June 2026.Environmental and lifestyle exposures reshape the cardiovascular epigenome through coordinated regulation of DNA methylation, histone modifications, noncoding RNAs, and RNA methylation (m6A). These multilayered mechanisms drive enhancer‐centered regulatory network remodeling and epigenomic plasticity in cardiovascular diseases, highlighting emerging ...
Wangzheqi Zhang +7 more
wiley +1 more source
Metabolic Regulation of Immune Responses: Molecular Mechanisms, Diseases, and Therapeutic Targets
MedComm, Volume 7, Issue 6, June 2026.FBP1 loss drives immune evasion and therapy resistance by enhancing glycolysis, STAT3 activation, and PD‐L1 expression, leading to T cell exhaustion and NK cell inhibition. FBP1 restoration, via LNP‐mRNA or epigenetic modulation, reverses these immunosuppressive effects, reactivates cytotoxic T cells, promotes M1 macrophage polarization, and enhances ...
Chunwei Li +10 more
wiley +1 more source
Increased complexity of circRNA expression during species evolution
, 2017 Circular RNAs (circRNAs) are broadly identified from precursor mRNA (pre-mRNA) back-splicing across various species. Recent studies have suggested a cell-/tissue- specific manner of circRNA expression. However, the distinct expression pattern of circRNAs
Rui Dong (432995) +3 more
core +1 more source
Encephalopathy: Cause, Pathogenesis, and Treatment
MedComm, Volume 7, Issue 6, June 2026.Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv +7 more
wiley +1 more source