Results 41 to 50 of about 1,797,821 (330)
Mechanisms of circular RNA degradation
Communications Biology, 2022 In this Perspective, Longxin Ren and co-authors summarise the role of circular RNAs in disease and discuss recent insights into how circular RNAs are metabolised in the cell.
Longxin Ren +7 more
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RNA Biology, 2019 Formed by back splicing or back fusion of linear RNAs, circular RNAs (circRNAs) constitute a new class of non-coding RNAs of eukaryotes. Recent studies reveal a spliceosome-dependent biogenesis of circRNAs where circRNAs arise at the intron-exon junctions of mRNAs.
Lihong Chen +12 more
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Circular RNA: A Potential Biomarker for Lung Cancer
Zhongliu Fangzhi Yanjiu, 2019 Circular RNA is a non-coding RNA that acts as a sponge for RNA, regulates cleavage and transcription, translates proteins and interacts with RNA-binding proteins.
XIAO Zhihao +3 more
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Circular RNAs in Human Cancer [PDF]
Frontiers in Oncology, 2021 Circular RNAs (circRNAs) are a class of endogenous single-stranded covalently closed RNAs, primarily produced from pre-mRNAs via non-canonical back-splicing. circRNAs are highly conserved, stable, and expressed in tissue- and development-specific pattern. circRNAs play essential roles in physiological process as well as cancer biology.
Yanjun Lu +3 more
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Circular RNA identified from Peg3 and Igf2r. [PDF]
PLoS ONE, 2018 Circular RNA is a newly discovered class of non-coding RNA generated through the back-splicing of linear pre-mRNA. In the current study, we characterized two circular RNAs that had been identified through NGS-based 5'RACE experiments.
Bambarendage P U Perera +2 more
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Engineering circular RNA for enhanced protein production
Nature Biotechnology, 2022 Protein expression from circular RNAs is enhanced several hundred-fold by optimizing vector design. Circular RNAs (circRNAs) are stable and prevalent RNAs in eukaryotic cells that arise from back-splicing.
Robert Chen +9 more
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Cancer Cell International, 2021 Background Circular RNAs (circRNAs) is a newly discovered type of non-coding RNA, the abnormal expression of which has been demonstrated in many types of human tumors.
Jing Han +5 more
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Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2
Nucleic Acids Research, 2016 Most RNAs generated by the human genome have no protein-coding ability and are termed non-coding RNAs. Among these include circular RNAs, which include exonic circular RNAs (circRNA), mainly found in the cytoplasm, and intronic RNAs (ciRNA ...
W. Du +5 more
semanticscholar +1 more source
Aging, 2019 In pace with the development of gene sequencing technology and transcriptome research, it has been found that 70 to 90% of the human genome is transcribed into RNAs, while only 2% of RNAs encode proteins. This implies that non-coding RNAs (ncRNAs) may exert vital biological functions and a full analysis of non-coding transcriptomes is needed.
Hui Jin +3 more
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Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2020 Skeletal muscles have an immense ability to regenerate from the muscle stem cells called satellite cells. The process of skeletal muscle regeneration is called myogenesis, which starts with activation of quiescent satellite cells immediately after muscle injury followed by proliferation and fusion of myoblasts into myotubes.
Debojyoti Das +4 more
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