Results 11 to 20 of about 2,065,768 (386)
Metastasis and circulating tumor cells [PDF]
EJIFCC, 2012 Cancer is a prominent cause of death worldwide. In most cases, it is not the primary tumor which causes death, but the metastases. Metastatic tumors are spread over the entire human body and are more difficult to remove or treat than the primary tumor ...
Dalum, G. van +2 more
core +4 more sources
Detection of Circulating Tumor Cells [PDF]
Scientifica, 2014 The increasing number of treatment options for patients with metastatic carcinomas has created an accompanying need for methods to determine if the tumor will be responsive to the intended therapy and to monitor its effectiveness.
Sanne de Wit +2 more
doaj +3 more sources
Proceedings of the National Academy of Sciences, 2013 A typical cancerous tumor contains millions or even billions of cells harboring genetic mutations driving them to grow, divide, and invade the local tissue in which they’re embedded. However, as the cells proliferate, they don’t all stay in the neighborhood.
Plaks, Vicki +2 more
openaire +6 more sources
Tumor Hypoxia and Circulating Tumor Cells [PDF]
International Journal of Molecular Sciences, 2020 Circulating tumor cells (CTCs) are a rare tumor cell subpopulation induced and selected by the tumor microenvironment’s extreme conditions. Under hypoxia and starvation, these aggressive and invasive cells are able to invade the lymphatic and circulatory systems.
Tinganelli W., Durante M.
openaire +5 more sources
Scientific Reports, 2023 Liquid biopsy (LB) provides a unique minimally invasive tool to follow-up cancer patients over time, to detect minimal residual disease (MRD), to study metastasis-biology and mechanisms of therapy-resistance.
Dimitra Stergiopoulou +8 more
doaj +1 more source
Diagnostics, 2021 The presence of contaminating gDNA in RNA preparations is a frequent cause of false positives in RT-PCR-based analysis. However, in some cases, this cannot be avoided, especially when there are no exons–intron junctions in the lncRNA sequences.
Athina N. Markou +3 more
doaj +1 more source
New insights into the correlations between circulating tumor cells and target organ metastasis
Signal Transduction and Targeted Therapy, 2023 Organ-specific metastasis is the primary cause of cancer patient death. The distant metastasis of tumor cells to specific organs depends on both the intrinsic characteristics of the tumor cells and extrinsic factors in their microenvironment.
Qinru Zhan +10 more
semanticscholar +1 more source
JAMA Oncology, 2015 Circulating Tumor Cells (CTC) are shed from primary or secondary tumors. Prior studies have demonstrated that enumeration of CTC is a robust independent prognostic factor of progression free and overall survival in patients with early and metastatic breast cancer.
Costanza, Paoletti, Daniel F, Hayes
openaire +3 more sources
Detection of circulating tumor cells: opportunities and challenges
Biomarker Research, 2022 Circulating tumor cells (CTCs) are cells that shed from a primary tumor and travel through the bloodstream. Studying the functional and molecular characteristics of CTCs may provide in-depth knowledge regarding highly lethal tumor diseases.
Siwei Ju +9 more
semanticscholar +1 more source