Results 21 to 30 of about 2,021,965 (393)
Using single-cell sequencing technology to detect circulating tumor cells in solid tumors
Molecular Cancer, 2021 Circulating tumor cells are tumor cells with high vitality and high metastatic potential that invade and shed into the peripheral blood from primary solid tumors or metastatic foci.
Jiasheng Xu +5 more
semanticscholar +1 more source
Molecular Oncology, 2021 MLL3 histone methyltransferase, encoded by the KMT2C gene, is a tumor suppressor that has an essential role in cell‐type‐specific gene expression.
Sofia Mastoraki +5 more
doaj +1 more source
Scientific Reports, 2021 Liquid biopsy is a tool to unveil resistance mechanisms in NSCLC. We studied changes in gene expression in CTC-enriched fractions of EGFR-mutant NSCLC patients under osimertinib.
Aliki Ntzifa +5 more
doaj +1 more source
Detection and relevance of epigenetic markers on ctDNA: recent advances and future outlook
Molecular Oncology, 2021 Liquid biopsy, a minimally invasive approach, is a highly powerful clinical tool for the real‐time follow‐up of cancer and overcomes many limitations of tissue biopsies.
Evi Lianidou
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Purpose: Monocarboxylate transporter 4 (MCT4) can influence the amount of lactate in the tumor microenvironment and further control cancer cell proliferation, migration, and angiogenesis.
Athina Markou +6 more
doaj +1 more source
Detection Methods and Clinical Applications of Circulating Tumor Cells in Breast Cancer
Frontiers in Oncology, 2021 Circulating Tumor Cells (CTCs) are cancer cells that split away from the primary tumor and appear in the circulatory system as singular units or clusters, which was first reported by Dr. Thomas Ashworth in 1869.
Hongyi Zhang +11 more
semanticscholar +1 more source
Circulating tumor cells in genitourinary tumors [PDF]
Therapeutic Advances in Urology, 2017 Management of advanced urogenital malignancies has profoundly changed in recent years due to the development of novel targeted drugs that have significantly improved patient’s clinical outcomes. This process has been made possible mainly thanks to better knowledge of tumor genetic alterations and molecular altered pathways.
Massari, Francesco +8 more
openaire +4 more sources
SnapShot: Circulating Tumor Cells [PDF]
Cell, 2017 Circulating tumor cells in the blood of patients are both signal flares for the existence of a tumor and harbingers of metastasis. With recent technological developments, these cells can be isolated and analyzed to provide insights into the biology of cancer spread and response to therapy and to offer new avenues for blood biomarker development.
Ged Brady, Caroline Dive
openaire +4 more sources
Epithelial Cell Adhesion Molecule: An Anchor to Isolate Clinically Relevant Circulating Tumor Cells
Cells, 2020 In the last few decades, the epithelial cell adhesion molecule (EpCAM) has received increased attention as the main membrane marker used in many enrichment technologies to isolate circulating tumor cells (CTCs).
Zahra Eslami-S +2 more
semanticscholar +1 more source
Biomedicines, 2023 The approval of monoclonal antibodies against programmed death-ligand 1 (PD-L1) and programmed cell death protein (PD1) has changed the landscape of cancer treatment. To date, many immune checkpoint inhibitors (ICIs) have been approved by the FDA for the
Areti Strati +3 more
doaj +1 more source