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Circulating Tumor DNA in Pediatric Cancer
Frontiers in Molecular Biosciences, 2022 The measurement of circulating tumor DNA (ctDNA) has gained increasing prominence as a minimally invasive tool for the detection of cancer-specific markers in plasma.
Louise Doculara +11 more
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Liquid biopsy in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA [PDF]
Molecular Cancer, 2019 Hepatocellular carcinoma (HCC) is one of the most common cancers and a leading cause of death worldwide. Due to latent liver disease, late diagnosis, and nonresponse to systemic treatments, surgical resection and/or biopsy specimens are still generally ...
Qianwei Ye +3 more
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Cell-free circulating tumor DNA in cancer [PDF]
Chinese Journal of Cancer, 2016 Cancer is a common cause of death worldwide. Despite significant advances in cancer treatments, the morbidity and mortality are still enormous. Tumor heterogeneity, especially intratumoral heterogeneity, is a significant reason underlying difficulties in
Zhen Qin +4 more
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Fragment Length of Circulating Tumor DNA.
PLoS Genetics, 2016 Malignant tumors shed DNA into the circulation. The transient half-life of circulating tumor DNA (ctDNA) may afford the opportunity to diagnose, monitor recurrence, and evaluate response to therapy solely through a non-invasive blood draw.
Hunter R Underhill +9 more
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Liquid Biopsy as a Method for Minimally Invasive Diagnosis of Thyroid Cancer [PDF]
Клиническая практика, 2023 Thyroid cancer is the 9th most common cancer in the world. The five-year survival rate for this disease is over 98%. However, in some patients there are cases of rapidly progressive treatment-resistant cancer that cannot be differed from poor-invasive ...
Tagir I. Rakhmatullin +3 more
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Role of circulating tumor DNA and circulating tumor cells in breast cancer: History and updates
SAGE Open Medicine, 2022 Circulating tumor DNA, cell-free DNA, and circulating tumor cells have been at the epitome of recent research in breast cancer. These forms of liquid biopsies have been used in monitoring disease progression, estimating the risk of relapse, and response ...
Julien Chedid +5 more
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Biosensors, 2022 While patients with resectable pancreatic ductal adenocarcinoma (PDAC) show improved survival compared to their non-resectable counterparts, survival remains low owing to occult metastatic disease and treatment resistance.
Pablo J. Dopico +7 more
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A fatal affair: Circulating tumor cell relationships that shape metastasis
iScience, 2021 Summary: Circulating tumor cells are metastatic precursors in several cancer types. Their biology and clinical utility are subject to numerous investigations, yet one aspect that is often neglected is their entanglement with the tumor microenvironment ...
Lauren L. Ozimski +2 more
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Early detection of recurrent HPV+ hypopharyngeal squamous cell carcinoma by circulating tumor DNA
Otolaryngology Case Reports, 2023 Circulating tumor DNA is a liquid biomarker that offers a highly specific method to assess HPV-associated tumor burden via a blood draw. It has the potential for many clinical applications in cancer care, including prognostication, monitoring treatment ...
Derek D. Kao +2 more
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Translational Oncology, 2023 Background: Detection of circulating tumor-derived material (cTM) in the peripheral blood (PB) of cancer patients has been shown to be useful in early diagnosis, prediction of prognosis, and disease monitoring.
Eva Kristine Ruud Kjær +4 more
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