Results 1 to 10 of about 519,260 (406)
Fragment Length of Circulating Tumor DNA. [PDF]
PLoS Genetics, 2016 Malignant tumors shed DNA into the circulation. The transient half-life of circulating tumor DNA (ctDNA) may afford the opportunity to diagnose, monitor recurrence, and evaluate response to therapy solely through a non-invasive blood draw.
Hunter R Underhill +9 more
doaj +6 more sources
Circulating Tumor DNA in Pediatric Cancer
Frontiers in Molecular Biosciences, 2022 The measurement of circulating tumor DNA (ctDNA) has gained increasing prominence as a minimally invasive tool for the detection of cancer-specific markers in plasma.
Louise Doculara +11 more
doaj +5 more sources
Clinical Applications of Circulating Tumor Cells and Circulating Tumor DNA as Liquid Biopsy. [PDF]
Cancer Discovery, 2016 UNLABELLED "Liquid biopsy" focusing on the analysis of circulating tumor cells (CTC) and circulating cell-free tumor DNA (ctDNA) in the blood of patients with cancer has received enormous attention because of its obvious clinical implications for ...
C. Alix-Panabières, K. Pantel
semanticscholar +6 more sources
Circulating DNA and Survival in Solid Tumors [PDF]
Cancer Epidemiology, Biomarkers & Prevention, 2015 Abstract Background: The ability to undertake molecular analysis to inform on prognosis and predictors of response to therapy is limited by accessibility of tissue. Measurement of total circulating free DNA (cfDNA) or circulating tumor DNA (ctDNA) in peripheral blood may allow easier access to tumor material and help to predict clinical ...
Alberto Ocaña +11 more
openalex +4 more sources
Liquid biopsy in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA [PDF]
Molecular Cancer, 2019 Hepatocellular carcinoma (HCC) is one of the most common cancers and a leading cause of death worldwide. Due to latent liver disease, late diagnosis, and nonresponse to systemic treatments, surgical resection and/or biopsy specimens are still generally ...
Qianwei Ye +3 more
doaj +4 more sources
Liquid biopsies: genotyping circulating tumor DNA.
Journal of Clinical Oncology, 2014 Genotyping tumor tissue in search of somatic genetic alterations for actionable information has become routine practice in clinical oncology. Although these sequence alterations are highly informative, sampling tumor tissue has significant inherent ...
L. Diaz, A. Bardelli
semanticscholar +6 more sources
Prospective assessment of circulating tumor DNA in patients with metastatic uveal melanoma treated with tebentafusp [PDF]
Nature CommunicationsTebentafusp, a bispecific immune therapy, is the only drug that demonstrated an overall survival benefit in patients with metastatic uveal melanoma (MUM).
Manuel Rodrigues +19 more
doaj +2 more sources
Cell-free circulating tumor DNA in cancer [PDF]
Chinese Journal of Cancer, 2016 Cancer is a common cause of death worldwide. Despite significant advances in cancer treatments, the morbidity and mortality are still enormous. Tumor heterogeneity, especially intratumoral heterogeneity, is a significant reason underlying difficulties in
Zhen Qin +4 more
doaj +4 more sources
PLoS ONE, 2015 Next-generation sequencing of cell-free circulating solid tumor DNA addresses two challenges in contemporary cancer care. First this method of massively parallel and deep sequencing enables assessment of a comprehensive panel of genomic targets from a ...
Richard B. Lanman +15 more
openalex +3 more sources
Electrochemical Biosensors for Circulating Tumor DNA Detection
Biosensors, 2022 Early diagnosis and treatment have always been highly desired in the fight against cancer, and detection of circulating tumor DNA (ctDNA) has recently been touted as highly promising for early cancer-screening.
Ke Wang +5 more
doaj +3 more sources