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Comprehensive characterization of circulating tumor cells and cell‐free DNA in patients with metastatic melanoma [PDF]
Advances in therapeutic approaches for melanoma urge the need for biomarkers that can identify patients at risk for recurrence and to guide treatment. The potential use of liquid biopsies in identifying biomarkers is increasingly being recognized.
Manouk K. Bos +11 more
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Liquid Biopsy as a Method for Minimally Invasive Diagnosis of Thyroid Cancer [PDF]
Thyroid cancer is the 9th most common cancer in the world. The five-year survival rate for this disease is over 98%. However, in some patients there are cases of rapidly progressive treatment-resistant cancer that cannot be differed from poor-invasive ...
Tagir I. Rakhmatullin +3 more
doaj +1 more source
Role of circulating tumor DNA and circulating tumor cells in breast cancer: History and updates
Circulating tumor DNA, cell-free DNA, and circulating tumor cells have been at the epitome of recent research in breast cancer. These forms of liquid biopsies have been used in monitoring disease progression, estimating the risk of relapse, and response ...
Julien Chedid +5 more
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While patients with resectable pancreatic ductal adenocarcinoma (PDAC) show improved survival compared to their non-resectable counterparts, survival remains low owing to occult metastatic disease and treatment resistance.
Pablo J. Dopico +7 more
doaj +1 more source
A fatal affair: Circulating tumor cell relationships that shape metastasis
Summary: Circulating tumor cells are metastatic precursors in several cancer types. Their biology and clinical utility are subject to numerous investigations, yet one aspect that is often neglected is their entanglement with the tumor microenvironment ...
Lauren L. Ozimski +2 more
doaj +1 more source
Early detection of recurrent HPV+ hypopharyngeal squamous cell carcinoma by circulating tumor DNA
Circulating tumor DNA is a liquid biomarker that offers a highly specific method to assess HPV-associated tumor burden via a blood draw. It has the potential for many clinical applications in cancer care, including prognostication, monitoring treatment ...
Derek D. Kao +2 more
doaj +1 more source
Background: Detection of circulating tumor-derived material (cTM) in the peripheral blood (PB) of cancer patients has been shown to be useful in early diagnosis, prediction of prognosis, and disease monitoring.
Eva Kristine Ruud Kjær +4 more
doaj +1 more source
The Role of Liquid Biopsy Analytes in Diagnosis, Treatment and Prognosis of Colorectal Cancer
Colorectal cancer (CRC) is one of the most common malignant tumors of the digestive tract worldwide and is a serious threat to human life and health. CRC occurs and develops in a multi-step, multi-stage, and multi-gene process, in which abnormal gene ...
JinHua He +8 more
doaj +1 more source
Detection of circulating tumor DNA is a new noninvasive technique with potential roles in diagnostic, follow-up, and prognostic evaluation of patients with many types of solid tumors.
Mariana Cartaxo Alves +8 more
doaj +1 more source
Circulating Tumor DNA in Pediatric Cancer
The measurement of circulating tumor DNA (ctDNA) has gained increasing prominence as a minimally invasive tool for the detection of cancer-specific markers in plasma.
Louise Doculara +11 more
doaj +1 more source

