Evidence of the neuroprotective role of citicoline in glaucoma patients [PDF]
, 2008 The glaucomatous disease is currently considered a disease involving ocular and visual brain structures. This new approach to glaucoma introduces the possibility of inducing an improvement by means of a pharmacological approach similar to that used in ...
Armington +55 more
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Citicoline in hypoxic ischemic encephalopathy in neonates: a randomized controlled trial
Italian Journal of Pediatrics, 2023 Background Hypoxic-ischemic encephalopathy (HIE) is one of the major complications that can lead to death or disability in neonates. We assessed the effect of citicoline as a neuroprotector in neonates with moderate and severe HIE.
Abeer Salamah +3 more
doaj +1 more source
Comparison of the National Institutes of Health Stroke Scale with disability outcome measures in acute stroke trials [PDF]
, 2005 <p><b>Background and Purpose:</b> Acute stroke trials typically use disability scales as their primary end point. Neurologic impairment scales such as the National Institutes of Health Stroke Scale (NIHSS) are possibly more sensitive to
Lees, K.R., Weir, C.J., Young, F.B.
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Concurrent analysis of Simvastatin and citicoline using a Reversed-phase High Performance Liquid Chromatography-Ultra Violet Method [PDF]
Trends in Pharmaceutical Sciences, 2019 To develop and evaluate a sensitive, accurate, rapid and reproducible high performance liquid chromatography analytical method for concurrent assay of simvastatin, a hyperlipidemia controlling agent, and citicoline, a psychostimulant agent, a C18 column (
Negin Mozafari +4 more
doaj +1 more source
The Virtual International Stroke Trials Archive [PDF]
, 2007 BACKGROUND AND PURPOSE: Stroke has global importance and it causes an increasing amount of human suffering and economic burden, but its management is far from optimal. The unsuccessful outcome of several research programs highlights the need for reliable
Ali, M. +19 more
core +3 more sources
Citicoline Protects Auditory Hair Cells Against Neomycin-Induced Damage
Frontiers in Cell and Developmental Biology, 2020 Aminoglycoside-induced hair cell (HC) loss is one of the most important causes of hearing loss. After entering the inner ear, aminoglycosides induce the production of high levels of reactive oxygen species (ROS) that subsequently activate apoptosis in ...
Zhenhua Zhong +18 more
doaj +1 more source
Citicoline on the Barthel Index
Indian Journal of Pharmacology, 2023 INTRODUCTION: Traumatic brain injury (TBI) is a paramount factor in mortality and morbidity. The clinical trials conducted to investigate the efficacy of neuroprotective agents, such as citicoline, as a therapeutic alternative for TBI have presented divergent findings.
Mahmoodkhani, Mehdi +4 more
openaire +2 more sources
Mild cognitive impairment treatment issues
Неврология, нейропсихиатрия, психосоматика, 2022 The development of dementia is preceded by mild cognitive impairment (MCI), the treatment of which can slow down the transformation of MCI into dementia. The article discusses drug and non-drug therapies for MCI.
L. A. Shсhepankevich +6 more
doaj +1 more source
Citicoline Ameliorates Neuro- and Genotoxicity Induced by Acute Malathion Intoxication in Rats [PDF]
Journal of Bioscience and Applied Research, 2019 Objective: In the present study, we explored the therapeutic potential of citicoline in preventing malathion induced neurotoxicity and genotoxicity. Citicoline has been shown to act as a neuroprotective in experimental animal models of ischemia and other
Asmaa Galal +4 more
doaj +1 more source
A Statistical Model for Stroke Outcome Prediction and Treatment Planning
, 2016 Stroke is a major cause of mortality and long--term disability in the world. Predictive outcome models in stroke are valuable for personalized treatment, rehabilitation planning and in controlled clinical trials.
Bhattacharya, Sakyajit +3 more
core +1 more source