Results 91 to 100 of about 7,469 (193)

Hypoxia‐preconditioned adipose‐derived mesenchymal stem cells‐derived exosomes transferring H19 obstruct neutrophil extracellular traps formation via HOXA5‐mediated inactivation of TLR4/NF‐κB/NLRP3 inflammatory signaling

Journal of Diabetes Investigation, Volume 17, Issue 8, Page 1283-1303, August 2026.
In this study, we uncovered that Hypo‐Exo transferring H19 promoted diabetic wound healing by repressing NETs formation via the miR‐130a/b‐3p/HOXA5 pathway to inactivate the TLR4/NF‐κB/NLRP3 inflammatory signaling. ABSTRACT Background Hypoxia‐stimulated adipose‐derived mesenchymal stem cells (ADSCs)‐derived exosomes (Hypo‐Exo) have a positive impact on
Li Qian, Xianxi Meng, Bairong Fang, Li Pi   +3 more
wiley   +1 more source

PAD-mediated citrullination is a novel candidate diagnostic marker and druggable target for HPV-associated cervical cancer

Frontiers in Cellular and Infection Microbiology
Citrullination is an emerging post-translational modification catalyzed by peptidyl-arginine deiminases (PADs) that convert peptidyl-arginine into peptidyl-citrulline. In humans, the PAD family consists of five isozymes (PADs 1-4, 6) involved in multiple
Camilla Albano, Matteo Biolatti, Jasenka Mazibrada, Selina Pasquero, Francesca Gugliesi, Irene Lo Cigno, Federica Calati, Greta Bajetto, Greta Bajetto, Greta Bajetto, Giuseppe Riva, Gloria Griffante, Gloria Griffante, Santo Landolfo, Marisa Gariglio, Marco De Andrea, Marco De Andrea, Valentina Dell’Oste   +17 more
doaj   +1 more source

Impact of increased Porphyromonas gingivalis peptidylarginine deiminase (PPAD) T2 variant allele on oral microbiota composition and severity of chronic periodontitis

Journal of Oral Microbiology
Background Porphyromonas gingivalis (Pg) is a keystone pathogen in periodontitis, encoding a unique peptidyl arginine deiminase (PPAD) linked to protein citrullination, a process associated with rheumatoid arthritis (RA).
Marta Kaminska, Noemie A.M. Dudzinska, Tülay Yucel-Lindberg, Birgitta Söder, Aswathy Narayanan, Jan Potempa, Piotr M. Mydel   +6 more
doaj   +1 more source

l-(+)Citrulline [PDF]

Biochemical Journal, 1939
A G, Gornall, A, Hunter
openaire   +2 more sources

Citrulline [PDF]

, 2020
openaire   +1 more source

Mapping the Substrate Specificity Landscape of PAD2 and PAD4 Enzymes. [PDF]

Chembiochem
Borbély A, Steckel A, Papp D, Pál D, Uray K, Gőz VG, Schlosser G.   +6 more
europepmc   +1 more source

Neutrophil Extracellular Trap Formation-Derived Peptidylarginine Deiminases in the Citrullination of Oral Bacteria to Promote Inflammation in Rheumatoid Arthritis. [PDF]

J Rheumatol
Acharya S, Brewer RC, Gomez AM, Younis S, Pandit M, Jahanbani S, Sharpe O, Love ZZ, Howard MC, Orange DE, Robinson WH.   +10 more
europepmc   +1 more source

Peptidylarginine deiminase 4-mediated citrullination in human disease: molecular mechanisms and therapeutic targeting. [PDF]

Front Pharmacol
Zou P, Su XD, Tian W, Xie XY, Yang K.
europepmc   +1 more source

NF-κB citrullination [PDF]

Nature Immunology, 2017
openaire   +2 more sources

Roles of peptidylarginine deiminase (PAD) and protein citrullination in viral infections. [PDF]

Front Microbiol
Wang K, Ma T, Ouyang M, Fei X, Yang L, Guo G.   +5 more
europepmc   +1 more source