Results 51 to 60 of about 10,819 (208)
, 2013 Mitglieder der Casein Kinase 1 (CK1) Familie üben regulatorische Funktionen in einer Vielzahl von zellulären Prozessen aus. Die Dysregulation von CK1 Isoformen, insbesondere von CK1d, kann zur Genese verschiedener Tumorentitäten beitragen, u.a.
Oltmer, Franziska Gesine
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Casein Kinase 1 Regulates Ethylene Synthesis by Phosphorylating and Promoting the Turnover of ACS5
Cell Reports, 2014 Summary: The casein kinase 1 (CK1) family participates in various cellular processes in eukaryotes, but CK1 function in higher plants remains largely unknown.
Shu-Tang Tan, Hong-Wei Xue
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Animal Models and Experimental Medicine, EarlyView.Overview illustration of dysregulated NFAT activation coordinating upstream signaling, post‐translational regulation and cancer promoting pathways to induce abnormal gene expression that drives tumor development, progression and immune escape. Abstract The Nuclear Factor of Activated T Cells (NFAT) family comprises closely related transcription factors.
Hira Khan +6 more
wiley +1 more source
Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2 [PDF]
The EMBO Journal, 2007 Protein kinase D2 (PKD2), a member of the PKD family of serine/threonine kinases, is localized in various subcellular compartments including the nucleus where the kinase accumulates upon activation of G-protein-coupled receptors. We define three critical post-translational modifications required for nuclear accumulation of PKD2 in response to ...
Von Blume, J. +8 more
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Frontiers in Cell and Developmental Biology, 2015 The prognosis of lymphoid neoplasms has improved considerably during the last decades. However, treatment response for some lymphoid neoplasms is still poor, indicating the need for new therapeutic approaches. One promising new strategy is the inhibition
Brigitte Sophia Winkler +9 more
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Frontiers in Cell and Developmental Biology, 2022 The migratory properties of leukemic cells are commonly associated with their pathological potential and can significantly affect the disease progression.
Štěpán Čada +11 more
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Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms
Medicinal Research Reviews, EarlyView.ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino +3 more
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Effect of Mechanized Ridge Tillage with Rice-Rape Rotation on Paddy Soil Structure
Agriculture, 2022 Ridge tillage is one of the essential tillage methods in China. It affects the soil structure by altering the soil-water environment. With the rapid development of agricultural mechanization, the mechanized ridge tillage technology that combines modern ...
Lanting Li +4 more
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Dynamic Behaviour of Bubbles in Oil Under Electrothermal Ageing
High Voltage, EarlyView.ABSTRACT During long‐term operation of converter transformers, the internal oil–pressboard insulation undergoes irreversible degradation. Partial discharge in the weakened insulation will cause the formation of a large number of bubbles in the insulating oil.
Hongbin Wu +7 more
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Sensitivity to the Auto-Phosphorylation Activity of CK1
, 2013 (A) Sensitivity of Thr34min to the autophosphorylation activity of CK1. The maximal values of the x-axis correspond to a very fast auto-inhibition of CK1, with effects identical to a Ser137Ala mutation, see red curve on Figure 10A.(B) Sensitivity of the ...
Éric Fernandez (23018) +3 more
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