Pharmacologic Treatment of Kleine-Levin Syndrome: A Case Report and Comprehensive Review of Therapeutic Options. [PDF]
A 12‐year‐old girl with Klein‐Levin syndrome showed central hypopneas and REM sleep without atonia on 24‐h polysomnography, which normalized after clarithromycin treatment alongside clinical remission. ABSTRACT Kleine–Levin syndrome (KLS) is a rare disorder with limited literature on treatment options and efficacy, especially in adolescents.
Thawongit S +2 more
europepmc +2 more sources
Tegoprazan-Based Triple Therapy for Helicobacter pylori Eradication: A Phase III Multicenter Randomized Clinical Trial. [PDF]
ABSTRACT Background Tegoprazan, a potassium‐competitive acid blocker, offers potent and sustained acid inhibition and potentially improves eradication efficacy. Aim This study aimed to evaluate the efficacy and safety of tegoprazan‐based triple therapy with two dosing regimens compared with that of lansoprazole‐based therapy for first‐line Helicobacter
Park JY +19 more
europepmc +2 more sources
An Open-Label Randomized Controlled Trial Comparing the Efficacy and Safety of a 7-Day Triple Therapy With Bismuth Versus 14-Day Standard Triple Therapy for Helicobacter pylori Eradication in Children and Adolescents. [PDF]
ABSTRACT Background To achieve eradication rates > 90%, the ESPGHAN/NASPGHAN guidelines for pediatric Helicobacter pylori infection recommend tailored antimicrobial therapy using sufficiently high doses over 10–14 days. However, prolonged treatment often leads to suboptimal compliance in children, which is a major contributor to reduced eradication ...
Šterbenc A +3 more
europepmc +2 more sources
Chromatographic-Based Binding and Thermodynamic Studies of Antibiotic Micropollutants with Humic Acid Using Affinity Microcolumns. [PDF]
ABSTRACT High‐performance affinity microcolumns with entrapped humic acid were utilized to investigate interactions between this natural carrier agent and several classes of antibiotics that are common emerging environmental contaminants, or micropollutants. Aldrich humic acid was used as a general model for this type of binding agent.
Sharmeen S +7 more
europepmc +2 more sources
Assessment of antimycobacterial activities of pure compounds extracted from Thai medicinal plants against clarithromycin-resistant Mycobacterium abscessus [PDF]
Background Infection with Mycobacterium abscessus is usually chronic and is associated with clarithromycin resistance. Increasing drug resistance is a major public-health problem and has led to the search for new antimycobacterial agents.
Auttawit Sirichoat +6 more
doaj +2 more sources
Comparison of omeprazole, metronidazole and clarithromycin with omeprazole/amoxicillin dual-therapy for the cure of Helicobacter pylori infection [PDF]
In this randomized, multicenter trial, we evaluated the effectiveness and side effect profile of a modified omeprazole-based triple therapy to cure Helicobacter pylori infection.
Bayerdörffer, Ekkehard +11 more
core +1 more source
CAQ Corner: Basic concepts of transplant immunology
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Background/Aims: Dual priming oligonucleotide-based multiplex polymerase chain reaction (DPO-PCR) has recently been used for both the detection of Helicobacter pylori and the identification of H.
Soo-Young Na +4 more
doaj +1 more source
.: Cabergoline is used in the treatment of Parkinson’s disease (PD). Clarithromycin is a potent inhibitor of CYP3A4 and P-glycoprotein and is often co-administered with cabergoline in usual clinical practice.
Akiko Nakatsuka +7 more
doaj +1 more source
Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera +4 more
wiley +1 more source

