Results 51 to 60 of about 56,119 (185)

The Effect of Cytochrome P450 and Organic Anion Transporter Polypeptide on Macrolides–Atorvastatin Drug Interaction

Iraqi Journal of Industrial Research
Cytochrome P450 (CYP3A4) enzymes and organic anion-transporting polypeptides (OATPs) are critical in drug pharmacokinetics. Fifteen rabbits were divided into three groups: the atorvastatin group received a single oral dose of atorvastatin (0.86 mg/kg B ...
Zainab Farooq Abdalhameed, Orooba Mohammed Saeed Ibrahim   +1 more
doaj   +1 more source

Efficacy and safety of clarithromycin as treatment for Mediterranean spotted fever in children: a randomized controlled trial [PDF]

, 2001
Fifty-one children with Mediterranean spotted fever (MSF) were randomized to receive either clarithromycin, 15 mg/kg/day orally in 2 divided doses, or chloramphenicol, 50 mg/kg/day orally in 4 divided doses, for 7 days.
CASCIO, ANTONIO, COLOMBA, Claudia, di Martino, L, Di Rosa, D, Salsa, L, TITONE LANZA DI SCALEA, Lucina   +5 more
core   +1 more source

Comparison of the impact of Helicobacter pylori eradication treatment with bismuth and non-bismuth quadruple regimens on the gut microbiota [PDF]

Microbiota in Health and Disease, 2019
Background: Helicobacter pylori eradication requires a combination of antibiotics. The short and long-term effect of different H. pylori eradication regimens on the gut microbiota has received little attention.
S. Prast-Nielsen, A. McNicholl, C. O’Morain, F. Megraud, J. Machado, T. Alarcon, M. Leja, A. Gasbarrini, L. Andersen, L. Engstrand, J. Gisbert, on behalf European Helicobacter and Microbiota Study Group (EHMSG; www.helicobacter.org)   +11 more
doaj   +1 more source

Identification of New Drug Candidates Against \u3cem\u3eBorrelia burgdorferi\u3c/em\u3e Using High-Throughput Screening [PDF]

, 2016
Lyme disease is the most common zoonotic bacterial disease in North America. It is estimated that .300,000 cases per annum are reported in USA alone. A total of 10%–20% of patients who have been treated with antibiotic therapy report the recrudescence of
Babar, Mustafeez Mujtaba, Inayathullah, Mohammed, Kim, K. M., Parekh, Mansi B., Pothineni, Venkata Raveendra, Rajadas, Jayakumar, Samineni, A. V., Solow-Cordero, David, Tayebi, Lobat, Wagh, Dhananjay   +9 more
core   +3 more sources

Role of MIC levels and 23S rRNA mutation sites to clarithromycin in 14-day clarithromycin bismuth quadruple therapy for Helicobacter pylori eradication: A prospective trial in Beijing

Heliyon
Background: Rising clarithromycin resistance undermines Helicobacter pylori (H. pylori) treatment efficacy. We aimed to determine clarithromycin's minimum inhibitory concentration (MIC) levels and identify specific mutation sites in the 23S ribosomal ...
Ying Chen, Siyu Li, Wenbin Li, Yiran Wang, Jihua Shi, Xue Xu, Pan Zhang, Dan Chen, Rui Gang, Qingfeng Luo   +9 more
doaj   +1 more source

Hospital management of community-acquired pneumonia in Malta [PDF]

, 2012
Community-acquired pneumonia (CAP) remains a common diagnosis requiring hospital admission and a leading cause of death worldwide. No local guideline is currently available for the management of CAP.
Callus, Roberta, Mamo, Jonathan, Micallef, Josef, Montefort, Stephen   +3 more
core  

Survey of general practitioners' knowledge about Helicobacter pylori infection [PDF]

, 2005
BACKGROUND: Helicobacter pylori, occurring throughout the world and causing gastroduodenal diseases, is one of the most common chronic bacterial agents in humans.
Canbaz, Sevgi, Leblebicioglu, Hakan, Peksen, Yildiz, Sunter, Ahmet Tevfik   +3 more
core   +3 more sources

Prevalence of Helicobacter pylori in symptomatic patients and detection of clarithromycin resistance using melting curve analysis [PDF]

, 2007
Background:Clarithromycin is often a component of combination therapies for Helicobacter pylori eradication; however, increases in resistance rates have decreased the success of the treatment.Objective:This study was designed to determine the prevalence ...
Ayse Demet Kaya, C. Elif Öztürk, Yusuf Akcan, Mustafa Behçet, A. Esra Karakoç, Mihriban Yücel, Müge Mısırlıoglu, Serdar Tuncer, Lee, Kaneko, Glupczynski, McLoughlin, Soltermann, Oleastro, Velapatino, Valentine, Chisholm, Yilmaz, Dunn, Kisioglu, Demiray, Blaser, Lo, Baglan, Versalovic, van Doorn, Lascols, Posteraro, Takahashi, Goldman, Graham, Kim, Megraud, Cheng, Perez Aldana, Kolaylı, Simsek, Can   +37 more
core   +1 more source

The study of mutation in 23S rRNA resistance gene of Helicobacter pylori to clarithromycin in patients with gastrointestinal disorders in Isfahan - Iran

Advanced Biomedical Research, 2014
Background: Helicobacter pylori antimicrobial resistance is an important factor responsible for treatment failure. The purpose of this study was evaluating the prevalence of point mutations in clarithromycin-resistant clinical isolates of H.
Farzad Khademi, Jamshid Faghri, Sharareh Moghim, Bahram Nasr Esfahani, Hossein Fazeli, Farkhondeh Poursina, Peyman Adibi, Masoumeh Madhi, Hajieh Ghasemian Safaei   +8 more
doaj   +1 more source

New and Improved Diagnostics for Detection of Drug-Resistant Pulmonary Tuberculosis. [PDF]

, 2011
PURPOSE OF REVIEW: Tuberculosis (TB) remains a global emergency and continues to kill 1.7 million people globally each year. Drug-resistant TB is now well established throughout the world and most TB patients are not being screened for drug resistance ...
Affolabi, Albert, Banerjee, Blakemore, Boehme, Brossier, Bwanga, Caws, Coronel, Drews, Ellner, Ellner, Farnia, Fears, Garza-González, Gupta, Helb, Hillemann, Kiet, Kim, Lemaire, Lin, Ling, Martin, Martin, Martin, Migliori, Migliori, Minion, Morcillo, Neonakis, Nicol, Pai, Palomino, Piersimoni, Sandgren, Sohn, Van Rie, Visalakshi, Visalakshi, Wallis, Wright   +41 more
core   +1 more source