Antibiotic Susceptibility and Clarithromycin Resistance Determinants in Helicobacter pylori in the Northeast of Spain: A One-Year Prospective Study [PDF]
Antibiotics, 2023 Helicobacter pylori is one of the most widespread infections, and it is reaching alarming resistance levels worldwide. The recommended first-line empirical treatment differs according to the local rate of clarithromycin resistance.
Saray Mormeneo Bayo +9 more
doaj +4 more sources
Clarithromycin resistance and 23S rRNA gene point mutations of Helicobacter pylori infection in children [PDF]
The Turkish Journal of Pediatrics, 2016 This study aims to evaluate Helicobacter pylori with clarithromycin resistant genotypes in Manisa region, Turkey. Two hundred patients, who received diagnosis of Helicobacter pylori infection histopathologically, were included.
Yeliz Çağan-Appak +5 more
doaj +2 more sources
Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions: a randomised, open-label, non-inferiority phase 3 trial [PDF]
Lancet, The, 2020 BACKGROUND: Buruli ulcer is a neglected tropical disease caused by Mycobacterium ulcerans infection that damages the skin and subcutis. It is most prevalent in western and central Africa and Australia.
William Thompson +2 more
exaly +5 more sources
The Contribution of Efflux Pumps in Mycobacterium abscessus Complex Resistance to Clarithromycin [PDF]
Antibiotics, 2019 The basis of drug resistance in Mycobacterium abscessus is still poorly understood. Nevertheless, as seen in other microorganisms, the efflux of antimicrobials may also play a role in M. abscessus drug resistance. Here, we investigated the role of efflux
Júlia S. Vianna +10 more
doaj +2 more sources
Genetic Evolution of Mycobacterium abscessus Conferring Clarithromycin Resistance during Long-Term Antibiotic Therapy [PDF]
Canadian Respiratory Journal, 2020 Objectives. Clarithromycin is recommended as the core agent for treating M. abscessus infections, which usually calls for at least one year of treatment course, facilitating the development of resistance.
Bing Li +6 more
doaj +2 more sources
Egyptian Journal of Medical Human Genetics, 2018 Background: Antibiotic resistance of Helicobacter pylori (H. pylori) treatment is on the rise, and is affecting the efficacy of current used therapeutic regimens. Aim: We aimed to enhance the understanding of antimicrobial resistance rates of H.
Manal Diab +8 more
doaj +2 more sources
Pyrosequencing analysis for rapid and accurate detection of clarithromycin resistance-associated mutations in Iranian Helicobacter pylori isolates [PDF]
BMC Research Notes, 2023 Background Treatment of Helicobacter pylori (H. pylori) infection has become challenging following the development of primary antibiotic resistance. A primary therapeutic regimen for H. pylori eradication includes clarithromycin; however, the presence of
Helia Alavifard +5 more
doaj +2 more sources
Genetic basis of clarithromycin resistance in Bacillus anthracis [PDF]
Microbiology SpectrumThe high-consequence pathogen Bacillus anthracis causes human anthrax and often results in lethal infections without the rapid administration of effective antimicrobial treatment.
Tucker Maxson +9 more
doaj +2 more sources
Effects of Primary Metronidazole and Clarithromycin Resistance to Helicobacter pylori on Omeprazole, Metronidazole, and Clarithromycin Triple-Therapy Regimen in a Region with High Rates of Metronidazole Resistance [PDF]
, 2003 The aim of this study was to investigate the effect of metronidazole resistance (MtzR) and clarithromycin resistance (CIaR) on the eradication rate for omeprazole, clarithromycin, and metronidazole triple-therapy regimen and on the development of ...
Wai Man Wong +13 more
openalex +4 more sources
A real-time PCR assay for rapid identification of inducible and acquired clarithromycin resistance in Mycobacterium abscessus. [PDF]
BMC Infect Dis, 2020 Sharma MK, La Y, Janella D, Soualhine H.
europepmc +4 more sources