Genetic basis of clarithromycin resistance in Bacillus anthracis [PDF]
Microbiology SpectrumThe high-consequence pathogen Bacillus anthracis causes human anthrax and often results in lethal infections without the rapid administration of effective antimicrobial treatment.
Tucker Maxson +9 more
doaj +4 more sources
Antibiotic Susceptibility and Clarithromycin Resistance Determinants in Helicobacter pylori in the Northeast of Spain: A One-Year Prospective Study [PDF]
Antibiotics, 2023 Helicobacter pylori is one of the most widespread infections, and it is reaching alarming resistance levels worldwide. The recommended first-line empirical treatment differs according to the local rate of clarithromycin resistance.
Saray Mormeneo Bayo +9 more
doaj +2 more sources
Molecular Characterization of Clarithromycin Resistance in Helicobacter pylori Strains. [PDF]
Turk J Gastroenterol, 2023 The purpose of this study was to determine the antimicrobial status of stocked clinical Helicobacter pylori isolates by using antibiotic gradient test and subsequently identify the mutations that cause clarithromycin resistance by DNA sequencing. Turkey is a transition zone between Europe and Asia; therefore, we also aimed to show both continents ...
Örsten S, Yılmaz E, Akyön Y.
europepmc +4 more sources
Genetic Evolution of Mycobacterium abscessus Conferring Clarithromycin Resistance during Long-Term Antibiotic Therapy [PDF]
Canadian Respiratory Journal, 2020 Objectives. Clarithromycin is recommended as the core agent for treating M. abscessus infections, which usually calls for at least one year of treatment course, facilitating the development of resistance.
Bing Li +6 more
doaj +2 more sources
Early genetic diagnosis of clarithromycin resistance in Helicobacter pylori. [PDF]
World J Gastroenterol, 2021 The drug resistance rate of clinical Helicobacter pylori (H. pylori) isolates has increased. However, the mechanism of drug resistance remains unclear. In this study, drug-resistant H. pylori strains were isolated from different areas and different populations of Chinese for genomic analysis.To investigate drug-resistant genes in H. pylori and find the
Li XH +9 more
europepmc +3 more sources
Clarithromycin Resistance in Helicobacter Pylori
Central Asian Journal of Medical Sciences, 2016 Objectives: Eradication rates of Helicobacter pylori with standard triple therapy are disappointing in studies from several countries. The main reason for failure was found to be bacterial resistance to one of the most commonly used antibiotics ...
Mandkhai Bolor-Erdene +2 more
doaj +2 more sources
Pyrosequencing analysis for rapid and accurate detection of clarithromycin resistance-associated mutations in Iranian Helicobacter pylori isolates [PDF]
BMC Research Notes, 2023 Background Treatment of Helicobacter pylori (H. pylori) infection has become challenging following the development of primary antibiotic resistance. A primary therapeutic regimen for H. pylori eradication includes clarithromycin; however, the presence of
Helia Alavifard +5 more
doaj +2 more sources
Helicobacter pylori clarithromycin resistance assessment: are gastric antral biopsies sufficient? [PDF]
Gastroenterology Insights, 2012 Gastric biopsy ssampling could affect accuracy of Helicobacter pylori clarithromycin resistance assessment due to coexistence of susceptible and resistant strains (i.e.
Vincenzo De Francesco +5 more
doaj +3 more sources
Whole-Genome Sequencing for Predicting Clarithromycin Resistance in Mycobacterium abscessus. [PDF]
Antimicrob Agents Chemother, 2019 AbstractMycobacterium abscessus is emerging as an important pathogen in chronic lung diseases with concern regarding patient to patient transmission. The recent introduction of routine whole genome sequencing (WGS) as a replacement for existing reference techniques in England provides an opportunity to characterise the genetic determinants of ...
Lipworth S +10 more
europepmc +5 more sources
Primary and secondary clarithromycin resistance in Helicobacter pylori and mathematical modeling of the role of macrolides [PDF]
Nature Communications, 2021 Éva Kocsmár +2 more
exaly +2 more sources