Results 11 to 20 of about 5,733 (175)
Two-dimensional PCR for detecting class 1, 2 and 3 integrons
Heliyon, 2022 Integrons can capture and express foreign gene cassettes through site-specific recombination and are important genetic elements in spreading antibiotic resistance genes among bacteria.
Wenwen Zhu +5 more
doaj +3 more sources
Definition of the attI1 site of class 1 integrons [PDF]
Microbiology, 2000 Integron-encoded integrases recognize two distinct types of recombination site: attI sites, found in integrons, and members of the 59-base element (59-be) family, found in the integron-associated gene cassettes. The class 1 integron integrase, IntI1, catalyses recombination between attI1 and a 59-be, two 59-be, or two attI1 sites, but events involving ...
Sally R, Partridge +5 more
openaire +5 more sources
Class 1 integron in staphylococci [PDF]
Molecular Biology Reports, 2011 As a major concern in public health, methicillin-resistant staphylococci (MRS) still remains one of the most prevalent pathogens that cause nosocomial infections throughout the world and has been recently labeled as a "super bug" in antibiotic resistance.
Zhenbo, Xu +3 more
openaire +2 more sources
Distinct ARG profiles associated with class 1 integrons in municipal and industrial wastewater treatment plants. [PDF]
Environ Sci EcotechnolZhang Y +5 more
europepmc +2 more sources
Resistance integrons: class 1, 2 and 3 integrons [PDF]
Annals of Clinical Microbiology and Antimicrobials, 2015 As recently indiscriminate abuse of existing antibiotics in both clinical and veterinary treatment leads to proliferation of antibiotic resistance in microbes and poses a dilemma for the future treatment of such bacterial infection, antimicrobial resistance has been considered to be one of the currently leading concerns in global public health, and ...
Deng, Yang +9 more
openaire +2 more sources
Screening Foodstuffs for Class 1 Integrons and Gene Cassettes. [PDF]
J Vis Exp, 2015 Antibiotic resistance is one of the greatest threats to health in the 21st century. Acquisition of resistance genes via lateral gene transfer is a major factor in the spread of diverse resistance mechanisms. Amongst the DNA elements facilitating lateral transfer, the class 1 integrons have largely been responsible for spreading antibiotic resistance ...
Waldron LS, Gillings MR.
europepmc +4 more sources
Environmental Isolate of Rahnella aquatilis Harbors Class 1 Integron [PDF]
Current Microbiology, 2015 The paper presents first description of class 1 integron in an environmental strain of Rahnella aquatilis, a rarely isolated Gram-negative bacterium of the family Enterobacteriaceae. The strain was isolated from the Warta river water, Poland. Class 1 integrase gene was detected by a PCR assay.
Koczura, Ryszard +2 more
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Class 1 integrons are low-cost structures in Escherichia coli. [PDF]
ISME J, 2017 Abstract Resistance integrons are bacterial genetic platforms that can capture and express antibiotic resistance genes embedded within gene cassettes. The capture and shuffling of gene cassettes are mediated by the integrase IntI, the expression of which is regulated by the SOS response in Escherichia coli.
Lacotte Y, Ploy MC, Raherison S.
europepmc +4 more sources
Molecular differentiation of common promoters in Salmonella class 1 integrons [PDF]
Journal of Microbiological Methods, 2007 The integron is a mobile gene element which harbors antibiotic-resistance gene cassettes capable of site-specific integration. Among the four known types of integrons, the class 1 integron has been associated with multidrug-resistance in pathogenic bacteria. These gene cassettes have been the focus of a series of studies.
Tae-Eun, Kim +7 more
openaire +2 more sources
“Distribution and functional identification of complex class 1 integrons”
Infection, Genetics and Evolution, 2013 The emergence of extended-spectrum β-lactamases and plasmid-mediated resistance to quinolones has been previously found to be associated with the dissemination of complex class 1 integrons in Argentina. In this study, we analyzed their distribution through time and evaluated the functionality of the Orf513 protein, which is the putative recombinase of ...
María Paula, Quiroga +6 more
openaire +4 more sources