Results 31 to 40 of about 114,464,069 (201)

Class 1 integrons are low-cost structures in Escherichia coli. [PDF]

ISME J, 2017
Abstract Resistance integrons are bacterial genetic platforms that can capture and express antibiotic resistance genes embedded within gene cassettes. The capture and shuffling of gene cassettes are mediated by the integrase IntI, the expression of which is regulated by the SOS response in Escherichia coli.
Lacotte Y, Ploy MC, Raherison S.
europepmc   +4 more sources

Impacts of anthropogenic activity on the ecology of class 1 integrons and integron-associated genes in the environment [PDF]

The ISME Journal, 2011
Abstract The impact of human activity on the selection for antibiotic resistance in the environment is largely unknown, although considerable amounts of antibiotics are introduced through domestic wastewater and farm animal waste. Selection for resistance may occur by exposure to antibiotic residues or by co-selection for mobile genetic ...
William H, Gaze, Lihong, Zhang, Nouradin A, Abdouslam, Peter M, Hawkey, Leo, Calvo-Bado, Jeremy, Royle, Helen, Brown, Susan, Davis, Paul, Kay, Alistair B A, Boxall, Elizabeth M H, Wellington   +10 more
openaire   +2 more sources

Activation of class 1 integron integrase is promoted in the intestinal environment

PLOS Genetics, 2022
Class 1 integrons are widespread genetic elements playing a major role in the dissemination of antibiotic resistance. They allow bacteria to capture, express and exchange antibiotic resistance genes embedded within gene cassettes. Acquisition of gene cassettes is catalysed by the class 1 integron integrase, a site-specific recombinase playing a key ...
Baltazar, Murielle, Bourgeois-Nicolaos, Nadège, Larroudé, Macarena, Couet, William, Uwajeneza, Solange, Doucet-Populaire, Florence, Ploy, Marie-Cécile, da Re, Sandra   +7 more
openaire   +5 more sources

Molecular characterization of class 1, 2 and 3 integrons in clinical multi-drug resistant Klebsiella pneumoniae isolates

Antimicrobial Resistance and Infection Control, 2019
Background The aim of this study was to characterize class 1,2 and 3 integrons in clinical MDR Klebsiella pneumoniae isolates in Kashan, Iran. Methods One hundred-eighty one Klebsiella pneumoniae were recovered from clinical specimens during November ...
Farzaneh Firoozeh, Zeinab Mahluji, Ahmad Khorshidi, Mohammad Zibaei   +3 more
doaj   +1 more source

Class 1 Integrons in Environments with Different Degrees of Urbanization

PLoS ONE, 2012
Les intégrons de classe 1 sont l'un des éléments les plus efficaces dans l'acquisition, l'expression et la propagation des gènes de résistance aux antimicrobiens (Arg) parmi les isolats cliniques. On sait peu de choses sur le flux génétique des composants des plates-formes génétiques des intégrons de classe 1 à l'intérieur et entre les communautés ...
Maximiliano Nardelli, Paula Marina Scalzo, María Soledad Ramírez, María Paula Quiroga, Marcelo H. Cassini, Daniela Centrón   +5 more
openaire   +5 more sources

An intrinsic control element for translational initiation in class 1 integrons [PDF]

Molecular Microbiology, 2002
SummaryIntegrons are genetic elements able to capture anti‐biotic resistance and other genes and to promote their transcription. Here, we have investigated integron‐dependent translation of an aminoglycoside 6′‐N‐acetyltransferase gene (aac(6′)‐Ib7) inserted at the attI1 site. N‐terminal sequencing revealed that translation of this gene was initiated
Béatrice, Hanau-Berçot, Isabelle, Podglajen, Isabelle, Casin, Ekkehard, Collatz   +3 more
openaire   +2 more sources

Identical Miniature Inverted Repeat Transposable Elements Flank Class 1 Integrons in Clinical Isolates of Acinetobacter spp. [PDF]

, 2013
Miniature inverted repeat transposable elements (MITEs) have been identified flanking class 1 integrons. We have identified and characterized a 439-bp MITE-like structure in seven Acinetobacter species isolates from Portugal and Brazil.
da Silva, Gabriela J., Nielsen, Kåre M., Toleman, Mark A., Domingues, Sara   +3 more
core   +1 more source

Investigation of class 1 integrons in Klebsiella pneumoniae clinical and microbiota isolates belonging to different phylogenetic groups in Recife, State of Pernambuco

Revista da Sociedade Brasileira de Medicina Tropical, 2014
Introduction The high prevalence of Klebsiella pneumoniae infections is related to the ability of K. pneumoniae to acquire and disseminate exogenous genes associated with mobile elements, such as R plasmids, transposons and integrons.
Alexsandra Maria Silva Lima, Maíra Espíndola Silva de Melo, Luiz Carlos Alves, Fábio André Brayner, Ana Catarina Souza Lopes   +4 more
doaj   +1 more source

Distribution of integrons and phylogenetic groups among highly virulent serotypes of Klebsiella pneumoniae in a Chinese tertiary hospital

Journal of Global Antimicrobial Resistance, 2020
Objectives: This study describes the distribution of integrons and phylogenetic groups among clinical highly virulent serotype (HVS) Klebsiella pneumoniae isolates in a Chinese tertiary hospital.
Wenjian Liao, Dan Li, Fangpeng Liu, Fang-ling Du, Dan Long, Wei Zhang, Yang Liu   +6 more
doaj   +1 more source

Integron, Plasmid and Host Strain Characteristics of Escherichia coli from Humans and Food Included in the Norwegian Antimicrobial Resistance Monitoring Programs. [PDF]

PLoS ONE, 2015
Antimicrobial resistant Escherichia coli (n=331) isolates from humans with bloodstream infections were investigated for the presence of class 1 and class 2 integrons.
Marianne Sunde, Gunnar Skov Simonsen, Jannice Schau Slettemeås, Inger Böckerman, Madelaine Norström   +4 more
doaj   +1 more source