Results 31 to 40 of about 877,938 (283)

Transcription of integron‐harboured gene cassette impacts integration efficiency in class 1 integron [PDF]

open access: bronzeMolecular Microbiology, 2011
SummaryClass 1 integrons play important roles in the dissemination of antibiotic resistance genes among bacteria. Generally, class 1 integron consists of an integrase gene (intI1), a recombination site (attI1) and a promoter (Pc) that drives the transcription of the downstreamed gene cassettes.
Quhao Wei   +6 more
openalex   +3 more sources

Complex class 1 integrons harboring CTX-M-2-encoding genes in clinical Enterobacteriaceae from a hospital in Brazil

open access: goldJournal of Infection in Developing Countries, 2015
Introduction: CTX-M enzymes are the most prevalent extended-spectrum beta-lactamases (ESBLs) in Brazil and around the world. The spread of CTX-M lies in their ability to be mobilized by insertion sequences and integrons.
Milena Dropa   +4 more
doaj   +3 more sources

Molecular Characterization of Class 1 Integrons in Carbapenem-Resistant Enterobacteriaceae Isolates

open access: greenSSRN Electronic Journal, 2022
Carbapenem-resistant Enterobacterales (CRE) infections result in higher treatment costs and mortality rates. Integrons play important roles in emergence and spread of antibiotic resistant genes. To get a better understand on the effects of integron on CRE resistance, distribution of common carbapenemase genes and class 1 integron in clinical CRE ...
tong wang   +4 more
openalex   +3 more sources

High-Throughput Screening of Antimicrobial Resistance Genes and Their Association With Class 1 Integrons in Urban Rivers in Japan

open access: yesFrontiers in Environmental Science, 2022
Antimicrobial resistance (AMR) is a serious public health concern. Many countries have implemented AMR surveillance programs for humans and animals, but a scheme for monitoring AMR in the environment has not yet been established. Class 1 integrons, which
I. Kasuga   +4 more
semanticscholar   +1 more source

Definition of the attI1 site of class 1 integrons [PDF]

open access: yesMicrobiology, 2000
Integron-encoded integrases recognize two distinct types of recombination site: attI sites, found in integrons, and members of the 59-base element (59-be) family, found in the integron-associated gene cassettes. The class 1 integron integrase, IntI1, catalyses recombination between attI1 and a 59-be, two 59-be, or two attI1 sites, but events involving ...
Sally R, Partridge   +5 more
openaire   +5 more sources

Class 1 integron in staphylococci [PDF]

open access: yesMolecular Biology Reports, 2011
As a major concern in public health, methicillin-resistant staphylococci (MRS) still remains one of the most prevalent pathogens that cause nosocomial infections throughout the world and has been recently labeled as a "super bug" in antibiotic resistance.
Zhenbo, Xu   +3 more
openaire   +2 more sources

Screening Foodstuffs for Class 1 Integrons and Gene Cassettes. [PDF]

open access: yesJ Vis Exp, 2015
Antibiotic resistance is one of the greatest threats to health in the 21st century. Acquisition of resistance genes via lateral gene transfer is a major factor in the spread of diverse resistance mechanisms. Amongst the DNA elements facilitating lateral transfer, the class 1 integrons have largely been responsible for spreading antibiotic resistance ...
Waldron LS, Gillings MR.
europepmc   +4 more sources

Resistance integrons: class 1, 2 and 3 integrons [PDF]

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2015
As recently indiscriminate abuse of existing antibiotics in both clinical and veterinary treatment leads to proliferation of antibiotic resistance in microbes and poses a dilemma for the future treatment of such bacterial infection, antimicrobial resistance has been considered to be one of the currently leading concerns in global public health, and ...
Deng, Yang   +9 more
openaire   +2 more sources

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