Class 1 integrons are low-cost structures in Escherichia coli [PDF]
ISME J, 2017 Abstract Resistance integrons are bacterial genetic platforms that can capture and express antibiotic resistance genes embedded within gene cassettes. The capture and shuffling of gene cassettes are mediated by the integrase IntI, the expression of which is regulated by the SOS response in Escherichia coli.
Yohann Lacotte, M. Ploy, S. Raherison
semanticscholar +5 more sources
Evolution of class 1 integrons: Mobilization and dispersal via food-borne bacteria [PDF]
PLoS One, 2017 Class 1 integrons have played a major role in the global dissemination of antibiotic resistance. Reconstructing the history of class 1 integrons might help us control further spread of antibiotic resistance by understanding how human activities influence
Timothy M. Ghaly +4 more
semanticscholar +2 more sources
Antimicrobial resistance patterns and prevalence of class 1 and 2 integrons in
Gut Pathogens, 2010 Background Shigella is a frequent cause of bacterial dysentery in the developing world. Treatment with effective antibiotics is recommended for shigellosis, but options become limited due to globally emerging resistance.
Madiyarov Ruslan S +7 more
doaj +2 more sources
Antibiotic-Resistant Escherichia coli and Class 1 Integrons in Humans, Domestic Animals, and Wild Primates in Rural Uganda [PDF]
Appl Environ Microbiol, 2018 Antibiotic resistance is a global problem. This study, conducted in rural western Uganda, describes antibiotic resistance patterns in Escherichia coli bacteria near two forested national parks. Resistance was present not only in people, but also in their
D. Weiss +6 more
semanticscholar +2 more sources
Acquisition and transfer of antibiotic resistance genes in association with conjugative plasmid or class 1 integrons of Acinetobacter baumannii [PDF]
PLoS One, 2018 Conjugation is a type of horizontal gene transfer (HGT) that serves as the primary mechanism responsible for accelerating the spread of antibiotic resistance genes in Gram-negative bacteria.
Udomluk Leungtongkam +3 more
semanticscholar +2 more sources
“Distribution and functional identification of complex class 1 integrons”
Infection, Genetics and Evolution, 2013 The emergence of extended-spectrum β-lactamases and plasmid-mediated resistance to quinolones has been previously found to be associated with the dissemination of complex class 1 integrons in Argentina. In this study, we analyzed their distribution through time and evaluated the functionality of the Orf513 protein, which is the putative recombinase of ...
María Paula, Quiroga +6 more
exaly +6 more sources
Characterization of the resistance class 1 integrons in Staphylococcus aureus isolates from milk of lactating dairy cattle in Northwestern China [PDF]
BMC Vet Res, 2018 BackgroundIntegrons are mobile DNA elements and they have an important role in acquisition and dissemination of antimicrobial resistance genes. However, there are limited data available on integrons of Staphylococcus aureus (S.
Longping Li, Xin Zhao
semanticscholar +2 more sources
Gene Expression in Class 2 Integrons Is SOS-Independent and Involves Two Pc Promoters
Frontiers in Microbiology, 2017 Integrons are powerful bacterial genetic elements that permit the expression and dissemination of antibiotic-resistance gene cassettes. They contain a promoter Pc that allows the expression of gene cassettes captured through site-specific recombination ...
Thomas Jové +4 more
doaj +3 more sources
Journal of Infection and Public Health, 2017 BACKGROUND The overexpression of efflux pumps and existence of class 1 integrons are the most important mechanisms that contribute to antimicrobial resistance in Pseudomonas aeruginosa especially in burn and Intensive Care Units (ICUs). The present study
Hamid Reza Goli +7 more
openalex +2 more sources
Interrelationship between tetracycline resistance determinants, phylogenetic group affiliation and carriage of class 1 integrons in commensal Escherichia coli isolates from cattle farms [PDF]
BMC Vet Res, 2018 BackgroundCarriage of antibiotic-resistant foodborne pathogens by food production animals is one of many contributors to treatment failure in health care settings, and it necessitates an integrated approach to investigate the carriage of resistant ...
K. M. Belaynehe, Seung-Won Shin, H. Yoo
semanticscholar +2 more sources