Revising CX3CR1 Expression on Murine Classical and Non-classical Monocytes [PDF]
In mice, monocytes (Mo) are conventionally described as CX3CR1low classical Mo (CMo) and CX3CR1high non-classical Mo (NCMo) based on the expression of EGFP in Cx3cr1+/EGFP mice and by analogy with human CX3CR1 expression.
Aïda Meghraoui-Kheddar +4 more
doaj +3 more sources
In-Depth Proteomic Characterization of Classical and Non-Classical Monocyte Subsets [PDF]
Monocytes are bone marrow-derived leukocytes that are part of the innate immune system. Monocytes are divided into three subsets: classical, intermediate and non-classical, which can be differentiated by their expression of some surface antigens, mainly ...
Víctor Segura +18 more
doaj +9 more sources
Immune complex-induced haptokinesis in human non-classical monocytes. [PDF]
Formation and deposition of immune complexes (ICs) are hallmarks of various autoimmune diseases. Detection of ICs by IC receptors on leukocytes induces downstream signaling and shapes the local immune response. In many cases the pathological relevance of ICs is not well understood.
Preuß SL +7 more
europepmc +5 more sources
Patrolling Mechanics of Non-Classical Monocytes in Vascular Inflammation [PDF]
Non-classical monocytes have emerged as the preeminent vascular housekeepers. Continuous intravascular screening is enabled by slow patrolling on the endothelium and allows a rapid response to local perturbations. Intravital imaging has been crucial to elucidate the molecular mechanisms and migratory phenotype of patrolling.
Konrad Buscher +3 more
openalex +4 more sources
Role of non-classical monocytes in HIV-associated vascular cognitive impairment [PDF]
ABSTRACTDespite antiretroviral treatment (cART), people living with HIV (PLWH) are more susceptible to neurocognitive impairment (NCI), probably due to synergistic/additive contribution of traditional cerebrovascular risk factors. Specifically, altered blood brain barrier (BBB) and transmigration of inflammatory monocytes are risk factors for ...
Meera V. Singh +16 more
openalex +3 more sources
CEACAM 1, 3, 5 and 6 -positive classical monocytes correlate with interstitial lung disease in early systemic sclerosis. [PDF]
Yokoyama K +11 more
europepmc +3 more sources
Gene deficiency in activating Fcγ receptors influences the macrophage phenotypic balance and reduces atherosclerosis in mice [PDF]
Immunity contributes to arterial inflammation during atherosclerosis. Oxidized low-density lipoproteins induce an autoimmune response characterized by specific antibodies and immune complexes in atherosclerotic patients.
Egido, J. +9 more
core +16 more sources
Monocyte adaptations in patients with obesity during a 1.5 year lifestyle intervention
BackgroundObesity is associated with chronic, low-grade inflammation, which is reflected in altered peripheral blood monocyte characteristics. The aim of this study was to analyze the monocyte subset composition (classical (CM), intermediate (IM) and non-
Eline S. van der Valk +9 more
doaj +1 more source
Resolvin D2 restores monocyte anisocytosis and mediates a shift toward classical monocytes ex vivo in blood samples from patients after major burns. [PDF]
Nazemidashtarjandi S +8 more
europepmc +3 more sources

