Results 61 to 70 of about 1,360,367 (244)

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Decrease in non-classical monocytes in Myasthenia Gravis patients

, 2022
International audienceCirculating monocytes are mononuclear cells which are highly specialized in phagocytosis and antigen presentation, secrete a large range of different cytokines, and migrate to the tissues in response to infection and injury ...
Le Panse, Rozen, Verdier, Julien, Berrih-Aknin, Sonia, Truffault, Frédérique, Demeret, Sophie, Hemery, Edouard   +5 more
core  

Altered co-stimulatory and inhibitory receptors on monocyte subsets in patients with visceral leishmaniasis.

PLoS Neglected Tropical Diseases
Visceral leishmaniasis (VL) is a neglected tropical disease caused by parasites from the Leishmania (L.) donovani complex. VL is characterised by uncontrolled parasite replication in spleen, liver and bone marrow, and by an impaired immune response and ...
Emebet Adem, Endalew Yizengaw, Tadele Mulaw, Endalkachew Nibret, Ingrid Müller, Yegnasew Takele, Pascale Kropf   +6 more
doaj   +1 more source

Nanoporous Silica Embedded in Nanoporous Platinum: A Versatile Composite Coating for Implant‐Associated Drug Delivery From Neuronal Electrodes

Advanced Materials Technologies, EarlyView.
Nanoporous silica nanoparticles incorporated in nanoporous platinum offer the possibility for implant‐associated drug delivery from neuronal electrodes. ABSTRACT Sensorineural hearing loss, resulting from damage to the hair cells of the inner ear, profoundly impairs quality of life.
Mosaieb Habib, Tim‐Joshua Strauß, Jennifer Harre, Madeleine Goblet, Florian Klodwig‐Kirstein, Jana Schwieger, Michaela Kreienmeyer, Verena Scheper, Athanasia Warnecke, Nina Ehlert, Peter Behrens   +10 more
wiley   +1 more source

Image_2_The slan antigen identifies the prototypical non-classical CD16+-monocytes in human blood.pdf

, 2023
IntroductionPeripheral monocytes in humans are conventionally divided into classical (CL, CD14++CD16−), intermediate (INT, CD14++CD16+) and non-classical (NC, CD14dim/−CD16++) cells, based on their expression levels of CD14 and CD16.
Francisco Bianchetto-Aguilera (5106320), Marco Tripodi (70526), Claudia Montaldo (2087254), Nicola Tamassia (12873), Monica Castellucci (17293531), Sara Gasperini (5106326), Alessio Grimaldi (2575351), Elisa Gardiman (5106314), Federica Calzetti (5106311), Vincenzo Barnaba (156821), Ilaria Signoretto (17293528), Marco Antonio Cassatella (9960239)   +11 more
core   +1 more source

Dynamic alterations in monocyte numbers, subset frequencies and activation markers in acute and convalescent COVID-19 individuals

Scientific Reports, 2021
Monocytes are thought to play an important role in host defence and pathogenesis of COVID-19. However, a comprehensive examination of monocyte numbers and function has not been performed longitudinally in acute and convalescent COVID-19.
Anuradha Rajamanickam, Nathella Pavan Kumar, Arul Nancy Pandiarajan, Nandhini Selvaraj, Saravanan Munisankar, Rachel Mariam Renji, Vijayalakshmi Venkatramani, Manoj Murhekar, Jeromie W. V. Thangaraj, Muthusamy Santhosh Kumar, C. P. Girish Kumar, Tarun Bhatnagar, Manickam Ponnaiah, R. Sabarinathan, V. Saravanakumar, Subash Babu   +15 more
doaj   +1 more source

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source

Mechanisms by which interleukin-4 suppresses inflammatory cytokine production by activated human monocytes [PDF]

, 2011
Improving understanding of how inflammatory responses by monocytes and macrophages are regulated may aid in the development of more targeted therapies for chronic inflammatory disease.
Woodward, Eleanor
core  

HMG-CoA reductase inhibitors deplete circulating classical and non-classical monocytes following human heart transplantation

, 2008
Background: Monocytes mediate immune responses following solid organ transplantation via cytokine secretion and differentiation to macrophage/dendritic cell lineages.
S.M. Shaw, C.T. Leonard, Mitsidou, A., Williams, S. G., Leonard, C. T., N. Yonan, Shaw, S. M., Fildes, J. E., J.E. Fildes, K. Rogacev, S.G. Williams, Yonan, N., Rogacev, K., A. Mitsidou   +13 more
core   +1 more source

Image_1_The slan antigen identifies the prototypical non-classical CD16+-monocytes in human blood.pdf

, 2023
IntroductionPeripheral monocytes in humans are conventionally divided into classical (CL, CD14++CD16−), intermediate (INT, CD14++CD16+) and non-classical (NC, CD14dim/−CD16++) cells, based on their expression levels of CD14 and CD16.
Francisco Bianchetto-Aguilera (5106320), Marco Tripodi (70526), Claudia Montaldo (2087254), Nicola Tamassia (12873), Monica Castellucci (17293531), Sara Gasperini (5106326), Alessio Grimaldi (2575351), Elisa Gardiman (5106314), Federica Calzetti (5106311), Vincenzo Barnaba (156821), Ilaria Signoretto (17293528), Marco Antonio Cassatella (9960239)   +11 more
core   +1 more source