Supplemental Digital Content is available in the text. Objective: Few studies of population-based cohorts have investigated prospective associations of lymphoid and myeloid cell subsets in cardiovascular disease onset and progression. The purpose of this
Matthew J. Feinstein +17 more
semanticscholar +1 more source
Summary of findings relating gene expression in classical, intermediate, and non-classical monocytes with HIV infection and subclinical CVD. [PDF]
Summary of findings relating gene expression in classical, intermediate, and non-classical monocytes with HIV infection and subclinical CVD.
Karin Mueller (579839) +21 more
core +1 more source
Altered monocyte expression and expansion of non-classical monocyte subset in IgA nephropathy patients [PDF]
The main defect of immunoglobulin A nephropathy (IgAN) lies within the immune system and in peripheral blood mononuclear cells rather than in the kidney. Previously, we found an altered gene expression in monocytes compared with B and T cells isolated from IgAN patients; thus, our aim here has been to study this subset at a genome-wide and functional ...
Cox, Sharon N. +6 more
openaire +3 more sources
Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection. [PDF]
Monocytes and T-cells are critical to the host response to acute bacterial infection but monocytes are primarily viewed as amplifying the inflammatory signal.
Mitchell, T.J. +68 more
core +1 more source
Towards a refined definition of monocyte subsets
In a nomenclature proposal published in 2010 monocytes were subdivided into classical and nonclassical cells and in addition an intermediate monocyte subset was proposed.
Loems eZiegler-Heitbrock +1 more
doaj +1 more source
The impact of acute strenuous exercise on TLR2, TLR4 and HLA.DR expression on human blood monocytes induced by autologous serum [PDF]
Acute exercise alters the surface expression of toll-like receptors (TLRs) and HLA.DR on blood monocytes, which could transiently compromise immunity.
O’Connor, Daniel P. +9 more
core +1 more source
Background Monocytes are a heterogenous population of immune cells whose subsets and functions become substantially dysregulated with advanced age. Although much of our current understanding of the age-related changes in monocytes is derived from fasting
Ryan G. Snodgrass +2 more
doaj +1 more source
Additional analyses of monocytes reveals diversity of surface expression on classical, intermediate, and non-classical monocytes. [PDF]
A. Examples of monocyte gating from a healthy volunteer control and DLBCL patient. Mononuclear cells were gated from CD45+ WBCs ([WBCs]). CD14+ monocytes were gated from [MNCs].
Allan B. Dietz (709538) +7 more
core +1 more source
Peripheral blood monocytes are heterogeneous CD14+ cell population, some of which also express CD16 molecule. Differences in phenotype between monocyte subpopulations can affect their functional activity, as well as the ability to further differentiate ...
T. V. Tyrinova +6 more
doaj +1 more source
Targeting immunosuppressive classical monocytes prevents immunotherapy resistance
B. L. Rodriguez +13 more
semanticscholar +2 more sources

