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Activation of the Classic and Alternate Complement Pathways by Endotoxin

The Journal of Immunology, 1974
Abstract The ability of bacterial endotoxin (LPS) to activate the complement system was studied in guinea pig serum (GPS). In serum chelated with ethyleneglycol tetraacetic acid (EGTA) 10 mM, which permits alternate complement pathway activation but inhibits classic complement pathway activation, lysis of LPS-coated sheep erythrocytes (E-
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Synthesis of classical pathway complement components by chondrocytes.

Immunology, 1996
Using immunohistochemical studies, C1q, C1s, C4 and C2 were detected in chondrocytes in normal human articular cartilage and macroscopically normal articular cartilage from the inferior surfaces of hip joints of patients with osteoarthritis. Using reverse-transcribed polymerase chain reaction (RT-PCR), mRNA for C1q, C1s, C4 and C2 was also detected in ...
Bradley, K.   +6 more
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CLASSICAL COMPLEMENT PATHWAY IN HIV INFECTION

The Lancet, 1989
G, Senaldi   +5 more
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The classical pathway of complement

The Biomedical & Life Sciences Collection, 2017
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