Results 51 to 60 of about 660,625 (335)

Classical and alternative complement pathway activation by pneumococci [PDF]

open access: yesInfection and Immunity, 1977
Sixty-two strains of Streptococcus pneumoniae were studied for their abilities to consume selected components of classical and alternative complement pathways in human sera. The classical pathway was blocked by chelating calcium with ethyleneglycol-bios (beta-aminoethyl ether)-N,N-tetraacetic acid and by removing C4. The alternative pathway was blocked
W P Reed   +2 more
openaire   +2 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Algebraic Structure of Classical Field Theory: Kinematics and Linearized Dynamics for Real Scalar Fields

open access: yes, 2019
We describe the elements of a novel structural approach to classical field theory, inspired by recent developments in perturbative algebraic quantum field theory.
Brunetti, Romeo   +2 more
core   +1 more source

A Quantum Computer Architecture using Nonlocal Interactions [PDF]

open access: yes, 2003
Several authors have described the basic requirements essential to build a scalable quantum computer. Because many physical implementation schemes for quantum computing rely on nearest neighbor interactions, there is a hidden quantum communication ...
Brennen, Gavin K.   +2 more
core   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

A New Tool for Complement Research: In vitro Reconstituted Human Classical Complement Pathway

open access: yesFrontiers in Immunology, 2018
The complement, as part of the innate immune system, represents the first line of defense against Gram-negative bacteria invading the bloodstream. The complement system is a zymogen cascade that ultimately assemble into the so-called membrane attack ...
Michele Mutti   +4 more
doaj   +1 more source

Cost‐effectiveness of multiparametric magnetic resonance imaging and MRI‐guided biopsy in a population‐based prostate cancer screening setting using a micro‐simulation model

open access: yesCancer Medicine, 2021
Background The introduction of multiparametric magnetic resonance imaging (mpMRI) and MRI‐guided biopsy has improved the diagnosis of prostate cancer. However, it remains uncertain whether it is cost‐effective, especially in a population‐based screening ...
Abraham M. Getaneh   +2 more
doaj   +1 more source

The phylogeny of the complement system and the origins of the classical pathway

open access: hybridImmunobiology, 2007
The origins of the complement system have now been traced to near to the beginnings of multi-cellular animal life. Most of the evidence points to the earliest activation mechanism having been more similar to the lectin pathway than to the alternative pathway.
Alister W. Dodds, Misao Matsushita
openalex   +4 more sources

Observing classical nucleation theory at work by monitoring phase transitions with molecular precision. [PDF]

open access: yes, 2014
It is widely accepted that many phase transitions do not follow nucleation pathways as envisaged by the classical nucleation theory. Many substances can traverse intermediate states before arriving at the stable phase. The apparent ubiquity of multi-step
Durán-Olivencia, MA   +4 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

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