Results 31 to 40 of about 686,133 (287)
The immunopathological functions associated with human C1q are still growing in terms of novelty, diversity, and pathologic relevance. It is, therefore, not surprising that C1q is being recognized as an important molecular bridge between innate and ...
Berhane Ghebrehiwet +3 more
doaj +1 more source
The complement system is a major constituent of the innate immune system. It not only bridges innate and adaptive arms of the immune system but also links the immune system with the coagulation system.
Hany Ibrahim Kenawy +2 more
doaj +1 more source
Dual pathway spindle assembly increases both the speed and the fidelity of mitosis [PDF]
Roughly half of all animal somatic cell spindles assemble by the classical prophase pathway, in which the centrosomes separate ahead of nuclear envelope breakdown (NEBD).
Cross, R. A. +2 more
core +2 more sources
Role of mitochondria in Parkinson disease [PDF]
The cause of the selective degeneration of nigrostriatal neurons in Parkinson disease (PD) has remained largely unknown. Exceptions include rare missense mutations in the alpha-synuclein gene on chromosome 4, a potentially pathogenic mutation affecting ...
Graeber, M. B. +4 more
core +1 more source
Bacterial infections are frequent and severe in patients with diabetes mellitus. Whether diabetes per se induces functional alterations in the complement system hampering activation during infection is unknown.
László József Barkai +6 more
doaj +1 more source
Classical analysis of correlated multiple ionization in strong fields
We discuss the final stages of the simultaneous ionization of two or more electrons due to a strong laser pulse. An analysis of the classical dynamics suggests that the dominant pathway for non-sequential escape has the electrons escaping in a symmetric ...
Bruno Eckhardt +2 more
core +1 more source
Is there a classical nonsense-mediated decay pathway in trypanosomes? [PDF]
In many eukaryotes, messenger RNAs with premature termination codons are destroyed by a process called "nonsense-mediated decay", which requires the RNA helicase Upf1 and also, usually, an interacting factor, Upf2.
Praveen Delhi +4 more
doaj +1 more source
Estrogens can alter the biology of various tissues and organs, including the brain, and thus play an essential role in modulating homeostasis. Despite its traditional role in reproduction, it is now accepted that estrogen and its analogues can exert ...
Zsombor Koszegi, Rachel Y. Cheong
doaj +1 more source
Properdin and factor H: Opposing players on the alternative complement pathway "see-saw" [PDF]
This article has been made available through the Brunel Open Access Publishing Fund.Properdin and factor H are two key regulatory proteins having opposite functions in the alternative complement pathway.
Abdul-Aziz, M +5 more
core +1 more source
Fibrosis is the final common pathway of inflammatory diseases in various organs. The inflammasomes play an important role in the progression of fibrosis as innate immune receptors.
Wen-Juan Zhang +5 more
doaj +1 more source

