Results 51 to 60 of about 359,057 (288)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
SMSs inhibit the classical, lectin and alternative pathway. [PDF]
, 2012 Complement deposition assays were performed on microtiter plates coated with aggregated IgG (classical pathway), mannan (lectin pathway) and zymosan (alternative pathway) in presence or absence of scabies mite serpins, respectively. Shown are means ± SEM
Katja Fischer (152079) +11 more
core +1 more source
Frontiers in Immunology, 2021 Fibrosis is the final common pathway of inflammatory diseases in various organs. The inflammasomes play an important role in the progression of fibrosis as innate immune receptors.
Wen-Juan Zhang +5 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Serum amyloid P aids complement-mediated immunity to Streptococcus pneumoniae [PDF]
, 2007 The physiological functions of the acute phase protein serum amyloid P (SAP) component are not well defined, although they are likely to be important, as no natural state of SAP deficiency has been reported.
Brown, JS +7 more
core
Nonclassical Testosterone Signaling:A New Pathway Controlling Spermatogenesis? [PDF]
, 2016 Testosterone is the essential regulator of spermatogenesis [1]. Produced by the testicular Leydig cells in response to pituitary Luteinizing Hormone (LH) stimulation, testosterone mediates its effects by binding to its cognate receptor, the ligand ...
Smith, Lee, Smith, Lee B, Lee B. Smith
core +2 more sources
Novel Evasion Mechanisms of the Classical Complement Pathway [PDF]
The Journal of Immunology, 2016 Abstract Complement is a network of soluble and cell surface-associated proteins that gives rise to a self-amplifying, yet tightly regulated system with fundamental roles in immune surveillance and clearance. Complement becomes activated on the surface of nonself cells by one of three initiating mechanisms known as the classical, lectin,
Brandon L Garcia +3 more
openaire +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Complexes between C1q and C3 or C4: novel and specific markers for classical complement pathway activation [PDF]
, 2005 Classical pathway activation is often assessed by measuring circulating levels of activated C4. However, this parameter does not discriminate between activation through the classical or the lectin pathway.
Hart, M. +20 more
core +1 more source
Non-classical crystallization pathway of transition metal phosphate compounds [PDF]
, 2023 Here, we elucidate non-classical multistep crystallization pathways of transition metal phosphates from aqueous solutions. We followed precipitation processes of M-struvites, NH4MPO4∙6H2O, and M-phosphate octahydrates, M3(PO4)2∙8H2O, where M = Ni, Co ...
Stephanos, Karafiludis +7 more
core +1 more source