Results 21 to 30 of about 686,133 (287)

Formation of molecular oxygen in ultracold O + OH reaction [PDF]

, 2008
We discuss the formation of molecular oxygen in ultracold collisions between hydroxyl radicals and atomic oxygen. A time-independent quantum formalism based on hyperspherical coordinates is employed for the calculations.
Brian K. Kendrick, G. Quéméner, Goulven Quéméner, Naduvalath Balakrishnan, P. Langevin   +4 more
core   +3 more sources

Complement in the Initiation and Evolution of Rheumatoid Arthritis

Frontiers in Immunology, 2018
The complement system is a major component of the immune system and plays a central role in many protective immune processes, including circulating immune complex processing and clearance, recognition of foreign antigens, modulation of humoral and ...
V. Michael Holers, Nirmal K. Banda
doaj   +1 more source

Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]

, 2010
Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Keeble, Anthony H., Mitchell, Daniel A., Schmid, Ralf, Schwaeble, Wilhelm J., Wallis, Russell   +4 more
core   +1 more source

Multiple-Organ Complement Deposition on Vascular Endothelium in COVID-19 Patients

Biomedicines, 2021
Increased levels of circulating complement activation products have been reported in COVID-19 patients, but only limited information is available on complement involvement at the tissue level.
Paolo Macor, Paolo Durigutto, Alessandro Mangogna, Rossana Bussani, Luca De Maso, Stefano D’Errico, Martina Zanon, Nicola Pozzi, Pier Luigi Meroni, Francesco Tedesco   +9 more
doaj   +1 more source

Complement activation and protein adsorption by carbon nanotubes [PDF]

, 2006
As a first step to validate the use of carbon nanotubes as novel vaccine or drug delivery devices, their interaction with a part of the human immune system, complement, has been explored.
Flahaut, Emmanuel, Green, Malcolm L. H., Salvador-Morales, Carolina, Sim, Edith, Sim, Robert B., Sloan, Jeremy   +5 more
core   +2 more sources

Peptide inhibitor of complement C1 (PIC1), a novel suppressor of classical pathway activation: mechanistic studies and clinical potential

Frontiers in Immunology, 2014
The classical pathway of complement plays multiple physiological roles including modulating immunological effectors initiated by adaptive immune responses as well as an essential homeostatic role in the clearance of damaged self-antigens.
Julia A Sharp, Pamela H. Whitley, Kenji M. Cunnion, Kenji M. Cunnion, Neel Kumar Krishna, Neel Kumar Krishna   +5 more
doaj   +1 more source

Role of complement activation in anti-neutrophil cytoplasmic antibody-associated glomerulonephritis

Frontiers in Medicine, 2022
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is an autoimmune disease characterized by necrotizing inflammation of small or medium vessels, causing ANCA associated glomerulonephritis (AAGN).
Tadasu Kojima, Takashi Oda
doaj   +1 more source

The Role of Alpha 2 Macroglobulin in IgG-Aggregation and Chronic Activation of the Complement System in Patients With Chronic Lymphocytic Leukemia

Frontiers in Immunology, 2021
Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults in the western world. One of the treatments offered for CLL is immunotherapy.
Naseba Naseraldeen, Naseba Naseraldeen, Regina Michelis, Masad Barhoum, Masad Barhoum, Judith Chezar, Tamar Tadmor, Tamar Tadmor, Ariel Aviv, Lev Shvidel, Lev Shvidel, Adi Litmanovich, Mona Shehadeh, Galia Stemer, Ety Shaoul, Andrei Braester, Andrei Braester   +16 more
doaj   +1 more source

Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells [PDF]

, 2012
For a long time necrosis was thought to be an uncontrolled process but evidences recently have revealed that necrosis can also occur in a regulated manner.
Barna, Gabor, Bauer, Pal I., Dunai, Zsuzsanna A., Imre, Gergely, Korcsmaros, Tamas, Mihalik, Rudolf, Petak, Istvan   +6 more
core   +3 more sources

Chimeric Proteins Containing MAP-1 and Functional Domains of C4b-Binding Protein Reveal Strong Complement Inhibitory Capacities

Frontiers in Immunology, 2018
The complement system is a tightly regulated network of proteins involved in defense against pathogens, inflammatory processes, and coordination of the innate and adaptive immune responses.
Cecilie E. Hertz, Rafael Bayarri-Olmos, Nikolaj Kirketerp-Møller, Sander van Putten, Katrine Pilely, Mikkel-Ole Skjoedt, Peter Garred   +6 more
doaj   +1 more source