Results 71 to 80 of about 4,411,154 (387)

Classical analysis of correlated multiple ionization in strong fields

open access: yes, 2000
We discuss the final stages of the simultaneous ionization of two or more electrons due to a strong laser pulse. An analysis of the classical dynamics suggests that the dominant pathway for non-sequential escape has the electrons escaping in a symmetric ...
Bruno Eckhardt   +2 more
core   +1 more source

Quantum control via a genetic algorithm of the field ionization pathway of a Rydberg electron [PDF]

open access: yes, 2017
Quantum control of the pathway along which a Rydberg electron field ionizes is experimentally and computationally demonstrated. Selective field ionization is typically done with a slowly rising electric field pulse.
Carroll, Thomas J.   +5 more
core   +3 more sources

The dual nature of TDC – bridging dendritic and T cells in immunity

open access: yesFEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Role of mitochondria in Parkinson disease [PDF]

open access: yes, 1999
The cause of the selective degeneration of nigrostriatal neurons in Parkinson disease (PD) has remained largely unknown. Exceptions include rare missense mutations in the alpha-synuclein gene on chromosome 4, a potentially pathogenic mutation affecting ...
Graeber, M. B.   +4 more
core   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Classical complement pathway activation in membranoproliferative glomerulonephritis

open access: yesKidney International, 1976
Levels of components of the classical and alternative complement pathways and the activity of the C3 nephritic factor (C3NeF) were measured in serum specimens from patients with type I (subendothelial deposits) and type II (intramembranous dense deposits) membranoproliferative glomerulonephritis (MPGN) and the results compared with the levels in normal
Clark D. West   +2 more
openaire   +3 more sources

A modular quantum-classical framework for simulating chemical reaction pathways accurately [PDF]

open access: yesarXiv, 2022
A lot of progress has been made in recent times for simulating accurately the ground state energy of small molecules and their potential energy surface, using quantum-classical hybrid computing architecture. While these single point energy calculations are a significant milestone for quantum chemistry simulation on quantum hardware, a similarly ...
arxiv  

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

A New Tool for Complement Research: In vitro Reconstituted Human Classical Complement Pathway

open access: yesFrontiers in Immunology, 2018
The complement, as part of the innate immune system, represents the first line of defense against Gram-negative bacteria invading the bloodstream. The complement system is a zymogen cascade that ultimately assemble into the so-called membrane attack ...
Michele Mutti   +4 more
doaj   +1 more source

Collagen-binding Microbial Surface Components Recognizing Adhesive Matrix Molecule (MSCRAMM) of Gram-positive Bacteria Inhibit Complement Activation via the Classical Pathway*

open access: yesJournal of Biological Chemistry, 2013
Background: Collagen-binding MSCRAMMs from Gram-positive bacteria are adhesins and are virulence factors in several infectious diseases models. Results: Cna and related collagen-binding MSCRAMMs bind C1q and block activation of the classical complement ...
Mingsong Kang   +6 more
semanticscholar   +1 more source

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