Nephritic Factor of the Classical Pathway of Complement [PDF]
A factor, functionally characterized by its capacity to stabilize the normally labile classical pathway C3-converting complex of the classical pathway of complement, has been isolated from the serum of one patient with a case of acute glomerulonephritis, subsequent to a cutaneous infection.
Ph. Lesavre +4 more
openaire +3 more sources
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Quantum Diffusive Dynamics of Macromolecular Transitions
We study the role of quantum fluctuations of atomic nuclei in the real-time dynamics of non-equilibrium macro-molecular transitions. To this goal we introduce an extension of the Dominant Reaction Pathways (DRP) formalism, in which the quantum ...
Beccara, S. a +2 more
core +1 more source
Fingerprints of slingshot non-sequential double ionization on two-electron probability distributions [PDF]
We study double ionization of He driven by a near-single-cycle laser pulse at low intensities at 400 nm. Using a three-dimensional semiclassical model, we identify the pathways that prevail non-sequential double ionization (NSDI).
Emmanouilidou, Agapi +1 more
core +2 more sources
Mechanisms of pre-mRNA splicing: classical versus non-classical pathways.
Expression of genetic information proceeds through two major biological events, transcription and translation. However, in eukaryotic cells, the primary transcript (pre-mRNA) is not the template that the translational apparatus scans through, in order to produce the corresponding protein. Pre-mRNAs undergo several modifications (cap site addition, poly
openaire +4 more sources
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
The Art of Fault Injection [PDF]
Classical greek philosopher considered the foremost virtues to be temperance, justice, courage, and prudence. In this paper we relate these cardinal virtues to the correct methodological approaches that researchers should follow when setting up a fault ...
Benso, Alfredo, Di Carlo, Stefano
core
The spino-bulbar-cerebellar pathway: organization and neurochemical properties of spinal cells that project to the lateral reticular nucleus in the rat [PDF]
In addition to classical spinocerebellar pathways, the cerebellum receives information from the spinal cord indirectly via spino-bulbar-cerebellar systems. One of the structures in this pathway is the lateral reticular nucleus (LRt).
Huma, Zilli, Maxwell, David J.
core +2 more sources
Quantification of classical and non-classical crystallization pathways in calcite precipitation
Crystal precipitation from aqueous solution occurs through multiple pathways. Besides the classical ion-by-ion addition, non-classical crystallization mechanisms, such as multi-ion polymer and nano-particle attachment, could be of great significance under certain circumstances.
Zhongtian Zhang, Jiuyuan Wang
openaire +2 more sources
Classical and Non-Classical Thyroid Hormone Intracellular Pathways Involved in T Lymphoma Growth [PDF]
Abstract: Thyroid hormones (THs) are important regulators of cell physiology. They are essential for the normal development and growth of mammals, especially for the neural differentiation and the regulation of the metabolism and the immune system. THs also induce the proliferation of several cell types.
Barreiro Arcos, María Laura +7 more
openaire +3 more sources

