Results 1 to 10 of about 135,129 (369)

Association of the Hermansky-Pudlak syndrome type-3 protein with clathrin

BMC Cell Biology, 2005
Background Hermansky-Pudlak syndrome (HPS) is a disorder of lysosome-related organelle biogenesis characterized by oculocutaneous albinism and prolonged bleeding.
Gahl William A, Boissy Raymond E, Mommaas Mieke, Dorward Heidi, Westbroek Wendy, Helip-Wooley Amanda, Huizing Marjan   +6 more
doaj   +1 more source

Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1. [PDF]

, 2014
BST2/tetherin, an antiviral restriction factor, inhibits the release of enveloped viruses from the cell surface. Human immunodeficiency virus-1 (HIV-1) antagonizes BST2 through viral protein u (Vpu), which downregulates BST2 from the cell surface.
Guatelli, John, Jia, Xiaofei, Lewinski, Mary, Rizk, Maryan, Suarez, Marissa, Tokarev, Andrey, Weber, Erin, Xiong, Yong   +7 more
core   +1 more source

Rule-based modelling provides an extendable framework for comparing candidate mechanisms underpinning clathrin polymerisation [PDF]

, 2018
Polymerisation of clathrin is a key process that underlies clathrin-mediated endocytosis. Clathrin-coated vesicles are responsible for cell internalization of external substances required for normal homeostasis and life –sustaining activity.
A Banerjee, A Fotin, A Fotin, A Fotin, AJ Jin, AS Perelson, B Goldstein, BI Shraiman, BM Pearse, BM Pearse, D Leyton-Puig, EJ Ungewickell, F Ferreira, GJ Doherty, HT McMahon, I Pastan, J Colvinr, JD Wilbur, M Falk, M Girard, M Lampe, M Muthukumar, M Saleem, MI Monine, MW Sneddon, N Jung, O Avinoam, O Sorokina, PK Sorger, PN Dannhauser, PN Dannhauser, R Matthews, R Nossal, S Marino, S Schein, SM Smith, T Böcking, T Kirchhausen, V Danos, WK Otter den, WK Otter den, Y Saheki   +41 more
core   +2 more sources

Sprouty2 Regulates Endocytosis and Degradation of Fibroblast Growth Factor Receptor 1 in Glioblastoma Cells

Cells
The Sprouty (SPRY) proteins are evolutionary conserved modulators of receptor tyrosine kinase (RTK) signaling. SPRY2 inhibits fibroblast growth factor (FGF) signaling, whereas it enhances epidermal growth factor (EGF) signaling through inhibition of EGF ...
Barbara Hausott, Lena Pircher, Michaela Kind, Jong-Whi Park, Peter Claus, Petra Obexer, Lars Klimaschewski   +6 more
doaj   +1 more source

17β-Estradiol Inhibits PCSK9-Mediated LDLR Degradation Through GPER/PLC Activation in HepG2 Cells

Frontiers in Endocrinology, 2020
Plasma levels of PCSK9 are significantly higher in postmenopausal women. Pharmacologically increased estrogen levels have been shown to lower PCSK9 and LDL-C levels in animals and humans. The action of estrogen suggests that it has the ability to prevent
Wei Fu, Xiao-Ping Gao, Sheng Zhang, Yan-Ping Dai, Wen-Jun Zou, Li-Min Yue   +5 more
doaj   +1 more source

Mutations in human dynamin block an intermediate stage in coated vesicle formation [PDF]

, 1993
The role of human dynamin in receptor-mediated endocytosis was investigated by transient expression of GTP-binding domain mutants in mammalian cells. Using assays which detect intermediates in coated vesicle formation, the dynamin mutants were found to ...
Damke, Hanna, Meyerowitz, Elliot M., Redelmeier, Thomas E., Schmid, Sandra L., Tisdale, Ellen J., van der Bliek, Alexander M.   +5 more
core   +3 more sources

Influence of Fluctuating Membranes on Self-Assembly of Patchy Colloids

, 2012
A coarse-grained computational model is used to investigate the effect of a fluid membrane on patchy-particle assembly into biologically-relevant structures motivated by viral cores and clathrin.
Likos, Christos N., Matthews, Richard
core   +1 more source

Nanomanipulation of Ligand Nanogeometry Modulates Integrin/Clathrin-Mediated Adhesion and Endocytosis of Stem Cells [PDF]

, 2023
Bohan Yin, Qin Zhang, Jiaxiang Yan, Yingying Huang, Chuanqi Li, Jiareng Chen, Chunyi Wen, Siu Hong Dexter Wong, Mo Yang   +8 more
openalex   +1 more source

TPLATE recruitment reveals endocytic dynamics at sites of symbiotic interface assembly in arbuscular mycorrhizal interactions [PDF]

, 2019
Introduction: Arbuscular mycorrhizal (AM) symbiosis between soil fungi and the majority of plants is based on a mutualistic exchange of organic and inorganic nutrients.
Bonfante, Paola, Carotenuto, Gennaro, Chabaud, Mireille, Chiapello, Marco, Faccio, Antonella, Fiorilli, Valentina, Genre, Andrea, Russo, Giulia, Van Damme, Daniël, Volpe, Veronica   +9 more
core   +3 more sources

Intracellular trafficking and cellular uptake mechanism of PHBV nanoparticles for targeted delivery in epithelial cell lines [PDF]

, 2017
Indexación: Web of Science; Scopus; Scielo.Background: Nanotechnology is a science that involves imaging, measurement, modeling and a manipulation of matter at the nanometric scale.
Cabana-Brunod, M, Fuentes, JA, Gonzalez-Nilo, FD, Llancalahuen, FM, Maldonado-Biermann, F, Marquez-Miranda, V, Otero, C, Penaloza, JP, Reyes-Ramirez, R, Rodriguez-Diaz, M, Velasquez, LA, Vilos, C   +11 more
core   +1 more source