Results 1 to 10 of about 134,599 (345)

A functional study of AUXILIN-LIKE1 and 2, two putative clathrin uncoating factors in Arabidopsis [PDF]

open access: yesThe Plant Cell, 2018
Clathrin-mediated endocytosis (CME) is a cellular trafficking process in which cargoes and lipids are internalized from the plasma membrane into vesicles coated with clathrin and adaptor proteins. CME is essential for many developmental and physiological
Adamowski, Maciek   +5 more
core   +3 more sources

Of condensates and coats - reciprocal regulation of clathrin assembly and the growth of protein networks [PDF]

open access: yesNature Communications
Clathrin-mediated endocytosis is essential for membrane traffic, impacting a diverse range of cellular processes including cell signaling homeostasis, cell adhesion, and receptor recycling.
Brandon T. Malady   +10 more
doaj   +3 more sources

Characterization of Zika Virus Endocytic Pathways in Human Glioblastoma Cells [PDF]

open access: yesFrontiers in Microbiology, 2020
Zika virus (ZIKV) infections can cause microcephaly and neurological disorders. However, the early infection events of ZIKV in neural cells remain to be characterized. Here, by using a combination of pharmacological and molecular approaches and the human
Mei Li   +18 more
doaj   +3 more sources

A Novel Sequence in AP180 and CALM Promotes Efficient Clathrin Binding and Assembly. [PDF]

open access: yesPLoS ONE, 2016
The clathrin heavy chain N-terminal domain interacts with endocytic adapter proteins via clathrin binding motifs to assemble clathrin triskelia into cages. However, the precise mechanism of clathrin assembly is not yet known.
Lia Moshkanbaryans   +4 more
doaj   +1 more source

A CIE change in our understanding of endocytic mechanisms

open access: yesFrontiers in Cell and Developmental Biology, 2023
The past six decades have seen major advances in our understanding of endocytosis, ranging from descriptive studies based on electron microscopy to biochemical and genetic characterization of factors required for vesicle formation.
Daniel J. Rioux   +2 more
doaj   +1 more source

Dynamics and nanoscale organization of the postsynaptic endocytic zone at excitatory synapses

open access: yeseLife, 2022
At postsynaptic sites of neurons, a prominent clathrin-coated structure, the endocytic zone (EZ), controls the trafficking of glutamate receptors and is essential for synaptic plasticity.
Lisa AE Catsburg   +3 more
doaj   +1 more source

Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles

open access: yesScience Advances, 2020
Cryo-electron tomography reveals the conformational changes and clathrin interactions of AP2 during coated vesicle assembly. Clathrin-mediated endocytosis (CME) is crucial for modulating the protein composition of a cell’s plasma membrane. Clathrin forms
O. Kovtun   +4 more
semanticscholar   +2 more sources

The role of clathrin in post-golgi trafficking in toxoplasma gondii [PDF]

open access: yes, 2013
Apicomplexan parasites are single eukaryotic cells with a highly polarised secretory system that contains unique secretory organelles (micronemes and rhoptries) that are required for host cell invasion.
Ferguson, D.J.P.   +3 more
core   +13 more sources

Effects of the clathrin inhibitor Pitstop-2 on synaptic vesicle recycling at a central synapse in vivo

open access: yesFrontiers in Synaptic Neuroscience, 2022
Four modes of endocytosis and subsequent synaptic vesicle (SV) recycling have been described at the presynapse to ensure the availability of SVs for synaptic release.
Alp Paksoy   +5 more
doaj   +1 more source

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