Results 151 to 160 of about 79,602 (359)
Advanced Science, EarlyView.Oligosaccharides with defined glycosidic bonds drive divergent gut microbial succession and shape unique metabolic profiles. Absolute time‐series profiling with Bayesian generalized Lotka–Volterra modeling identifies bond‐specific microbial responders, while monoculture validation and metaproteomics reveal linkage‐matched transport and cleavage modules.
Xiaoxuan Lu +10 more
wiley +1 more source
Anti-claudin 18.2 antibody as new targeted therapy for advanced gastric cancer
Journal of Hematology & Oncology, 2017 Targeted therapy and immunotherapy have revolutionized treatment of various cancers in the past decade. Despite targeted therapy with trastuzumab in Her2-positive gastric cancer patients, survival has been dismal, mostly due to disease progression and ...
Prabhsimranjot Singh +2 more
semanticscholar +1 more source
The role of claudin-12 protein in myocardiac ischaemia
, 2018 A claudin (CLDN) fehérje család komponensei fontos szerepet töltenek be a szoros sejtkapcsolatok létrehozásában és szabályozásában. Az eddigi kutatások alapján 7 CLDN proteinről mondhatjuk el, hogy myocardialis eredetűek, amelyek közül a claudin-5-ről a ...
Szónok, Attila
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Representative photographs of colonic claudin-1, claudin-2 and claudin-3 immunostaining in mice.
, 2013 Moderate claudin-1 immunostaining was observed in colons from control group (A). The intensity was significantly decreased in colitis group (B), and increased when treated with AMD3100 (C).
Xian-Ming Xia (340280) +5 more
core +1 more source
Advanced Science, EarlyView.An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang +9 more
wiley +1 more source
Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia
Molecular Psychiatry, 2017 Schizophrenia is a neurodevelopmental disorder that affects up to 1% of the general population. Various genes show associations with schizophrenia and a very weak nominal association with the tight junction protein, claudin-5, has previously been ...
C. Greene +23 more
semanticscholar +1 more source
, 1892 [Vente. Livres. 1892-06-24 - 1892-06-25. Paris][Collection. Livres. Virmond, Londolphe de.
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Advanced Science, EarlyView.Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng +14 more
wiley +1 more source
Claudin-3 immunohistochemistry in adult WT and SCCx43KO-/- mice.
, 2018 (A) WT tubule showing an immunopositive reaction in the basal part at stage VIII of the seminiferous epithelium (arrows). Scale bar: 50 μm. The positive immunoreaction in the epididymis confirms the binding specificity of the antibody (A, inset).
Hagen Gasse (745678) +6 more
core +1 more source
SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells
Animal Models and Experimental Medicine, EarlyView.The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang +6 more
wiley +1 more source