Results 151 to 160 of about 56,637 (316)
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
iNew Medicine, EarlyView.ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
Les origines et les débuts de l'imprimerie à Bordeaux / par A. Claudin,...
, 1897 Avec mode ...
Claudin, Anatole (1833-1906). Auteur du texte
core
Immune Checkpoint Inhibitors Induce Intestinal Epithelial Injury and a Senescence‐Like Phenotype
iNew Medicine, EarlyView.ICI treatment promotes the infiltration of activated immune cells into the intestinal mucosa. This inflammatory microenvironment is associated with significant epithelial injury, characterized by the disruption of the epithelial barrier, the depletion of specialized secretory cell lineages, and the induction of a premature senescence phenotype ...
Juan Wang +7 more
wiley +1 more source
iNew Medicine, EarlyView.ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little +12 more
wiley +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
iNew Medicine, EarlyView.ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Frontiers in Veterinary ScienceGastrointestinal disease is a leading cause of death in mature horses. A lack of in vitro modeling has impeded the development of novel therapeutics. The objectives of this study were to develop and further characterize a small intestinal monolayer cell ...
Amy Stieler Stewart +6 more
doaj +1 more source
mRNA and protein expression levels of claudin-16 and claudin-19.
, 2013 a) Effect of cisplatin on renal mRNA expression levels of tight junction proteins claudin-16 and claudin-19. b) Expression of claudin-16 and claudin-19 protein in kidney tissue of rats was examined with Western blot analyses using claudin-16 and claudin ...
Gaëlle A. Boulet (209386) +4 more
core +1 more source
Interdisciplinary Medicine, EarlyView.MBB modulates the TNBC tumor microenvironment by targeting TAM/CXCL1 and facilitates anti‐PD‐L1 therapy by disrupting CAF barriers via its photothermal effect. This combined strategy subsequently enhances the efficacy of PD‐L1 mAb and suppresses TNBC progression, metastasis, and recurrence.
Bo Pan +12 more
wiley +1 more source
AnimalsFollowing the downregulation of testicular endocrine and germinative function by slow-release gonadotropin-releasing hormone (GnRH)-agonist implants, testicular functions are quickly restored after implant removal. As an intact blood–testis barrier (BTB)
Sandra Goericke-Pesch +10 more
doaj +1 more source