Results 141 to 150 of about 79,602 (359)
, 2013 (A) claudin-3 in control group, (B) claudin-3 in CXCL12 group, (C) claudin-3 in AMD3100 group; (D) claudin-5 in control group, (E) claudin-5 in CXCL12 group, (F) claudin-5 in AMD3100 group; (G) claudin-7 in control group, (H) claudin-7 in CXCL12 group ...
Xian-Ming Xia (340280) +5 more
core +1 more source
Claudins and hepatocellular carcinoma
Biomedicine & PharmacotherapyHepatocellular carcinoma (HCC) has a high incidence and dismal prognosis, making it a significant global health burden. To change this, the development of new therapeutic strategies is imminent. The claudin (CLDN) family, as key components of tight junctions (TJs), plays an important role in the initiation and development of cancer.
Wentao Wang +4 more
openaire +2 more sources
Advanced Science, EarlyView.Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li +17 more
wiley +1 more source
Claudin-1 and Claudin-3 as Molecular Regulators of Myelination in Leukoaraiosis Patients
, 2021 OBJECTIVES: Leukoaraiosis is described as white matter lesions that are associated with cognitive dysfunction, neurodegenerative disorders, etc. Myelin depletion is a salient pathological feature of, and the loss of oligodendrocytes is one of the most ...
Mei, Ainong +4 more
core +1 more source
Advanced Science, EarlyView.Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang +10 more
wiley +1 more source
Current OncologyGastric adenocarcinoma (GAC) continues to be a prevalent worldwide malignancy and a leading cause of cancer death, and it is frequently cited as incurable. Targeted therapy in GAC has lagged behind other solid tumors.
Jane E. Rogers, Jaffer Ajani
doaj +1 more source
Claudin-11 and occludin are major contributors to Sertoli cell tight junction function, in vitro
, 2016 The Sertoli cell tight junction (TJ) is the key component of the blood-testis barrier, where it sequesters developing germ cells undergoing spermatogenesis within the seminiferous tubules.
Marcel Dinger (544772) +4 more
core
Generierung und Charakterisierung Claudin 16 und Claudin 10 defizienter Mäuse [PDF]
, 2011 Claudin Tight Junction Proteine sind wichtige Komponenten für den parazellulären Ionentransport in Epithelien. In der Niere sind Claudine an der Ionenresorption im Rahmen der Urinbildung beteiligt.
Will, Constanze
core +1 more source