Results 141 to 150 of about 56,637 (316)

Serum Zonula Occludens-1 and Claudin-5 Levels in Patients with Insomnia Disorder: A Pilot Study

, 2023
Mei Fan, Fangyi Deng, Rui Tang, Yixian Cai, Xiaotao Zhang, Hongyao Li, Ting Xiang, Jiyang Pan Department of Psychiatry, Sleep Medicine Centre, The First Affiliated Hospital, Jinan University, Guangzhou, People’s Republic of ChinaCorrespondence: Jiyang ...
Li H, Pan J, Xiang T, Zhang X, Fan M, Tang R, Cai Y, Deng F   +7 more
core  

Representative photographs of colonic claudin-5, claudin-7 and claudin-8 immunostaining in mice.

, 2013
Intense claudin-5 immunostaining was observed in colons from control group (A). The intensity was significantly decreased in colitis group (B), and increased when treated with AMD3100 (C).
Xian-Ming Xia (340280), Bing-Bing Zou (340288), Ju Zhou (340283), Su-Wen Li (340287), Kai-Feng Hu (340284), Fang-Yu Wang (340282)   +5 more
core   +1 more source

MET Expression in Upper Gastrointestinal Adenocarcinoma: Prevalence, Prognostic Impact, and Implications for Anti‐MET Antibody‐Drug Conjugate Therapy

International Journal of Cancer, EarlyView.
ABSTRACT MET is an actionable receptor tyrosine kinase, and MET‐directed antibody–drug conjugates (ADCs) have recently entered clinical practice with FDA approval in non‐small cell lung cancer and are now being evaluated across gastrointestinal malignancies, with patient selection based on MET immunohistochemistry (IHC) 3+ membranous staining at ...
Tillmann Bedau, Thomas Zander, Hans Anton Schlößer, Hakan Alakus, Onur Mustafov, Reinhard Büttner, Christiane Bruns, Alexander Quaas   +7 more
wiley   +1 more source

Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers

, 2015
In epithelial/endothelial barriers, claudins form tight junctions, seal the paracellular cleft, and limit the uptake of solutes and drugs. The peptidomimetic C1C2 from the C-terminal half of claudin-1's first extracellular loop increases drug delivery ...
Staat, Christian, Andjelkovic, Anuska V, Dabrowski, Sebastian, Engelhardt, Britta, Coisne, Caroline Marie, Stamatovic, Svetlana M, Wolburg, Hartwig, Blasig, Ingolf E   +7 more
core   +1 more source

Regulatory Effects of Ammonium Chloride in an In Vitro Model of Hepatic Encephalopathy: Mechanisms Involving ACTA2‐Mediated Cytoskeletal Remodeling

iLABMED, EarlyView.
Hyperammonemic stress suppresses ACTA2 expression and induces F‐actin cytoskeletal remodeling in astrocytes. The resulting inhibition of FAK/c‐Src signaling contributes to apoptosis, G2/M arrest, AQP4‐mediated swelling and junction‐associated proteins dysregulation, revealing a central role for ACTA2‐dependent cytoskeletal dysfunction in hepatic ...
Yue Tang, Jia Liu, Chengrong Bian, Wenwen Yuan, Wang Zhang, Fan Feng, Boan Li   +6 more
wiley   +1 more source

Catalogue d'un choix de livres rares et curieux sur l'escrime, l'histoire de l'épée, le duel, la chasse..., provenant de la collection de feu M. Ed. de Beaumont,... / [expert] A. Claudin

, 1888
[Vente. Livres. 1888-06-06. Paris][Collection. Livres. Beaumont, Ed. de.

core  

Microbial keystone taxa and metabolic signatures in centenarians regulate intestinal homeostasis during aging

iMeta, EarlyView.
Clostridium scindens and its metabolite indole‐3‐acetic acid (IAA) are identified as a keystone taxon and metabolic signature in centenarians. Clostridium scindens enhances microbial network stability and produces IAA via its own amidase (AMIE) and aldehyde dehydrogenase (ALDH), thus promoting intestinal homeostasis by activating the aryl hydrocarbon ...
Wei‐Chuan Lin, Cui Zhang, He‐Hua Lei, Zheng Cao, Xin Gao, Wen‐Kai Yu, Xin‐Zhi Li, Qing‐Wei Xiang, Zhi‐Wen Zhang, Shi‐Fu Pang, Wei‐Fei Luo, Deng‐Hui Xie, Li‐Min Zhang, Gang Chen   +13 more
wiley   +1 more source

Emerging clinical significance of claudin-7 in colorectal cancer: a review

, 2018
Kun Wang, Chang Xu, Wenjing Li, Lei Ding Department of Oncology, Beijing Shijitan Hospital, Capital Medical University, Beijing, 100038, People’s Republic of China Abstract: Tight junctions (TJs) play an important role in maintaining cell polarity ...
Xu C, Li WJ, Wang K, Ding L
core  

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

Interrogações sobre a Revolução de Outubro

Lua Nova: Revista de Cultura e Política, 1990
Fernando Claudín
doaj   +1 more source