Results 131 to 140 of about 79,602 (359)

Tight junction protein expression from peritoneal dialysis effluent

open access: yesRenal Failure, 2019
Background: We hypothesized that tight junction (TJ) proteins may have a role in paracellular transport of solute and water in peritoneal dialysis (PD) patients.
Sua Kim   +3 more
doaj   +1 more source

Analysis of Xenopus laevis claudin (Xcla) Tight Junction Genes in Development

open access: yes, 2005
Eight Xenopus laevis claudin genes, Xcla1, Xcla4B, Xcla5, Xcla6, Xcla12, Xcla16, Xcla18 and Xcla19, were cloned and sequenced. Their normal mRNA expression was determined from cleavage stage to tadpole stage by whole mount in situ hybridization.
Xie, Jianzhen
core  

Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers [PDF]

open access: yes, 2015
In epithelial/endothelial barriers, claudins form tight junctions, seal the paracellular cleft, and limit the uptake of solutes and drugs. The peptidomimetic C1C2 from the C-terminal half of claudin-1's first extracellular loop increases drug delivery ...
Staat, Christian   +7 more
core   +1 more source

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

open access: yesAdvanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang   +12 more
wiley   +1 more source

Probiotics Prevents Sensitization to Oral Antigen and Subsequent Increases in Intestinal Tight Junction Permeability in Juvenile–Young Adult Rats

open access: yesMicroorganisms, 2019
Increased intestinal permeability is thought to underlie the pathogenesis of food allergy. We explore the mechanism responsible for changes in the morphology and function of the intestinal barrier using a rat model of food allergy, focusing on the ...
Janyerkye Tulyeu   +8 more
doaj   +1 more source

Catalogue des livres et estampes composant la bibliothèque de feu M. A. G***, de Nantes / [expert] A. Claudin

open access: yes, 1887
[Vente. Livres. 1887-03-30 - 1887-04-02. Paris][Collection. Livres. G***, A.. 1887]Référence bibliographique : Lugt, 46419Appartient à l’ensemble documentaire : VenteEST2Contient une table des matièresAvec mode ...

core  

Claudin-5 subcellular localization along the oxygen-glucose deprivation (OGD) and medium exchange.

open access: yes, 2019
Figs A-C show antibody staining of Claudin-5 under the different treatments. Bars = 10 μm. N = 1; n = 3. (D) For each condition, the intracellular signal intensity was estimated using ImageJ as described in the “Materials and methods” section. Bar graphs
Erica Tornabene (7274117)   +3 more
core   +1 more source

PARP Inhibitors plus Anlotinib as Bridging Therapy for Armored CAR‐T Cells in Ovarian Cancer Enhances Infiltration and Antitumor Efficacy

open access: yesAdvanced Science, EarlyView.
This study shows that a PARP inhibitor combined with anlotinib, administered as bridging therapy, preconditions the tumor microenvironment to enhance the infiltration and antitumor activity of subsequently infused CAR‐T cells across preclinical ovarian cancer models, supporting bridging therapy as a promising strategy to address limited CAR‐T cell ...
Huayi Li   +20 more
wiley   +1 more source

Claudin-based tight junctions are crucial for the mammalian epidermal barrier

open access: yesJournal of Cell Biology, 2002
The tight junction (TJ) and its adhesion molecules, claudins, are responsible for the barrier function of simple epithelia, but TJs have not been thought to play an important role in the barrier function of mammalian stratified epithelia, including the ...
M. Furuse   +8 more
semanticscholar   +1 more source

Catalogue de bons livres en belle condition de la bibliothèque de feu M. A. P... / [expert] A. Claudin

open access: yes, 1894
[Vente. Livres. 1894-01-25 - 1894-01-26. Paris][Collection. Livres. A. P., Monsieur.

core  

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