Results 211 to 220 of about 78,811 (306)

Neutrophil-secreted extracellular vesicles induce blood-brain barrier leakage and tight junction disruption. [PDF]

Fluids Barriers CNS
Arteaga-Blanco L, Beidokhti MN, Villalba N, Swaby L, Cha BJ, Kayisli C, Yao Y, Wu MH, Yuan SY.   +8 more
europepmc   +1 more source

The Role of Immune Infiltration and Oxidative Stress in the Progression of Cerebral Cavernous Malformation

Brain and Behavior, Volume 16, Issue 2, February 2026.
Mechanism of rupture hemorrhage in cerebral cavernous malformations. Environmental and immune factors promote the progression of lesions and induce the risk of abnormal formation or rupture of cerebrovascular vessels. Abstract Purpose of Review To review how the immune microenvironment and oxidative stress modulate the initiation, maturation, and ...
Xuesai Zhu, Yizhi Yao, Tengbo Yu, Xiao Xiao   +3 more
wiley   +1 more source

Correction: Microbial communities and tight junction protein expression in the gastrointestinal tract of feedlot cattle. [PDF]

Sci Rep
Young JD, Pinnell LJ, Wolfe CA, Scott MA, Lawrence TE, Cavasin JP, Ellis JA, Langsten KL, Richeson JT, Morley PS.   +9 more
europepmc   +1 more source

Modulating the Gut Microbiome as a Therapeutic Approach in Multiple Sclerosis: Implications for Gut‐Brain Interactions and Immune Pathways: A Narrative Review

Brain and Behavior, Volume 16, Issue 2, February 2026.
The gut microbiome in multiple sclerosis (MS) shows consistent depletion of short‐chain fatty acid (SCFA)‐producing bacteria, expansion of pro‐inflammatory species, and reduced levels of butyrate, propionate, and indole metabolites. These alterations increase intestinal permeability, disrupt immune balance, and contribute to blood–brain barrier ...
Husna Irfan Thalib, Nuha Fatima, Faaleha Heba Fakruddin, Hosna Hamidullah Ali, Sariya Khan, Mohammed Talha Mohammed Zubair, Mable Pereira, Fatma E. Sayed Hassan   +7 more
wiley   +1 more source

Extracellular Vesicles from Probiotic and Beneficial Escherichia coli Strains Exert Multifaceted Protective Effects Against Rotavirus Infection in Intestinal Epithelial Cells. [PDF]

Pharmaceutics
Cordero C, Caballero-Román A, Martínez-Ruiz S, Olivo-Martínez Y, Baldoma L, Badia J.   +5 more
europepmc   +1 more source

Gut microbiota and central nervous system's direct bidirectional regulation: The mechanisms of the gut–brain axis in irritable bowel syndrome

Clinical and Translational Discovery, Volume 6, Issue 1, February 2026.
Gut microbiota directly modulates central nervous system activity via vagal, sympathetic and sensory neural circuits. Brainstem nuclei integrate microbial signals to regulate gut motility, secretion and visceral sensitivity. DRG neurons and stress‐responsive pathways link microbial cues to host defence and epithelial homeostasis. Dysregulated gut–brain
Jinxia Zhai, Yingjie Li, Jiameng Liu, Cong Dai   +3 more
wiley   +1 more source

Tight junction disruption <i>via</i> claudin-6 overexpression promotes invasion and recurrence in high-grade endometrial tumors. [PDF]

World J Clin Oncol
Ebrahim NAA, Eissa TS, Hussein MA, Korany OM, Amin NH.   +4 more
europepmc   +1 more source

Microbial‐Immune Interplay in CNS Autoimmune Diseases: Lessons from Animal Models and Clinical Studies

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley   +1 more source

Indole-3-aldehyde Preserves Gingival Epithelial Barrier Structure and Function Via AhR/Nrf2 Signaling Pathway. [PDF]

Inflammation
Wu L, Wu S, Deng Y, Li J, Zhang C, Wang Y, Zhao C, Gao L.   +7 more
europepmc   +1 more source

Process Systems Engineering in Precision Medicine: Opportunities in Autologous CAR‐T Therapy

Engineering in Life Sciences, Volume 26, Issue 2, February 2026.
ABSTRACT Autologous chimeric antigen receptor (CAR)‐T therapies have given hope to many cancer patients whose other lines of treatment have failed. Unfortunately, limited manufacturing capability has resulted in many patients dying while on a waitlist.
B. Wayne Bequette
wiley   +1 more source