Results 241 to 250 of about 78,811 (306)

Automated real-time imaging of intestinal barrier integrity and molecular profiling for early outcome prediction in inflammatory bowel disease: endo-histo-barrier-omics study. [PDF]

J Crohns Colitis
Iacucci M, Majumder S, Zammarchi I, Santacroce G, Capobianco I, Pugliano CL, Chaudari U, Meseguer Esbri P, Hayes B, Crotty R, Aburto MR, Del Amor MR, Kolawole BB, Eckenberger J, Amamou A, Naranjo V, Grisan E, Ghosh S, Endo-Histo-Barrier-Omics Group.   +18 more
europepmc   +1 more source

Single‐nucleus RNA sequencing identifies a novel tenogenic heterologous differentiation in endometrial carcinosarcomas: implications for diagnosis and tumor classification

The Journal of Pathology, Volume 268, Issue 2, Page 227-242, February 2026.
Abstract Carcinosarcomas (CSs) are aggressive biphasic tumors characterized by epithelial and mesenchymal components, whose histogenesis and differentiation dynamics remain poorly understood. We present single‐nucleus RNA sequencing (snRNA‐seq) analysis of six CSs (five endometrial and one ovarian) and two normal endometrial samples, profiling over 96 ...
Silvia González‐Martínez, José Palacios, Irene Carretero‐Barrio, Val Fernández‐Lanza, Alfonso Cortés‐Salgado, Javier Román, Xavier Matias‐Guiu, Sonia Gatius, Javier Cortés, Belén Pérez‐Mies   +9 more
wiley   +1 more source

Altered distribution of tissue galectins correlates with mucosal dysregulation in SIV infection. [PDF]

J Immunol
Premeaux TA, Yeung ST, Johnson SD, Moar P, Byrareddy SN, Ndhlovu LC.   +5 more
europepmc   +1 more source

Integrated Multi‐Omic Analysis Identifies Altered Colonic Brush Border Profile as a Key Feature of Microscopic Colitis

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Microscopic colitis (MC), comprising lymphocytic colitis (LC) and collagenous colitis (CC), is an inflammatory bowel disease with increasing incidence. MC etiopathogenesis remains unknown; however, altered colonic epithelial integrity may underlie uncontrolled luminal antigen passage, triggering immuno‐inflammatory responses ...
Danila Guagnozzi, Ana Maria Gonzalez‐Castro, Yamile Zabana, Fernando Fernández‐Bañares, Andreas Münch, Eva Tristan, Juan‐José Lozano, Julia Sidorova, Beatriz Lobo, Carmen Alonso‐Cotoner, Elba Exposito, Alfredo J. Lucendo, Stefania Landolfi, Ana Benages, Ronald Llerena‐Castro, Maria Dolores Castillo Cejas, Joan Dot, Javier Santos, Maria Vicario   +18 more
wiley   +1 more source

Claudin proteins and hemorrhage severity in aneurysmal subarachnoid hemorrhage: Correlation with modified Fisher score but not functional outcome. [PDF]

Neurosurg Rev
Lenzser G, Szebeni GJ, Balogh F, Gémes N, Schwarcz A, Csecsei P.   +5 more
europepmc   +1 more source

Remote Pancreatic Response to Severe Polytrauma Correlates With Clinical Outcome

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Acute pancreatic injury can result from blunt or sharp force trauma, often leading to serious complications. While direct pancreatic trauma is associated with high rates of infection, organ failure, and mortality, little is known about the pancreas as a potential secondary target and remote trauma organ and thereby as a booster of ...
Rebecca Halbgebauer, Lisa Wohlgemuth, Jonas Wrba, Sonja Braumüller, Enes Kumral, Ludmila Lupu, Clara Morgenstern, Lucas Bettac, Sebastian Wiese, Benjamin Mayer, Paolo Cinelli, Daniel Rittirsch, Hans‐Christoph Pape, Francesco Roselli, Thomas Seufferlein, Alexander Kleger, Markus Breunig, Markus Huber‐Lang   +17 more
wiley   +1 more source

Probiotics and the intestinal tight junction barrier function. [PDF]

Front Cell Dev Biol
Ferris MM, Subitoni Antonio L, Al-Sadi R.   +2 more
europepmc   +1 more source

Resveratrol attenuates areca nut extract‐induced chronic colitis by suppressing pyroptosis of intestinal epithelial cells via modulating cGAS/STING signaling

VIEW, Volume 7, Issue 1, February 2026.
Areca nut extract (ANE), commonly consumed in some cultures, can damage gut cells by triggering inflammation and cell death through a pathway called cGAS‐STING. This leads to the release of harmful inflammatory substances and weakens the gut barrier. Our study shows that resveratrol, a natural compound found in foods like grapes, can block this harmful
Jing Zhang, Muhammad Tufail, Yu‐Qi Huang, Can‐Hua Jiang, Ning Li   +4 more
wiley   +1 more source

Nicotine exacerbates MASH via inducing intestinal dysbiosis and barrier dysfunction. [PDF]

Commun Biol
Yi F, Wang J, Chen Y, Xia Y, Zhou H, Huang Y, Shen Y, Fang S, Wang X, Zhang Y, Chen Y, Chen D.   +11 more
europepmc   +1 more source

Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging

Aging Cell, Volume 25, Issue 2, February 2026.
Aging impairs cerebrovascular health by driving mitochondrial dysfunction, oxidative stress, endothelial failure, and neurovascular uncoupling, leading to BBB breakdown and cognitive decline. In contrast, time‐restricted feeding/eating counteracts these mechanisms by restoring mitochondrial function, activating adaptive nutrient‐sensing pathways ...
Madison Milan, Eva Troyano‐Rodriguez, Jennifer Ihuoma, Sharon Negri, Rakesh Rudraboina, Aleksandra Kosmider, Shantipriya Awasthi, Priya Balasubramanian, Shannon Conley, Andriy Yabluchanskiy, Anna Csiszar, Zoltan Ungvari, Rafael de Cabo, Stefano Tarantini   +13 more
wiley   +1 more source